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| 1 | Optimization of phenol degradation by Candida tropicalis Z-04 using Plackett-Burman design and response surface methodology显示文摘Statistical experimental designs were used to optimize the process of phenol degradation by Candida tropicalis Z-04,isolated from phenol-degrading aerobic granules.The most important factors influencing phenol degradation (p<0.05),as identified by a two-level Plackett-Burman design with 11 variables,were yeast extract,phenol,inoculum size,and temperature.Steepest ascent method was undertaken to determine the optimal regions of these four significant factors.Central composite design (CCD) and response surface analysis were adopted to further investigate the mutual interactions between these variables and to identify their optimal values that would generate maximum phenol degradation.The analysis results indicated that interactions between yeast extract and temperature,phenol and temperature,inoculum size and temperature affected the response variable (phenol degradation) significantly.The predicted results showed that the maximum removal efficiency of phenol (99.10%) could be obtained under the optimum conditions of yeast extract 0.41 g/L,phenol 1.03 g/L,inoculum size 1.43% (V/V) and temperature 30.04°C.These predicted values were further verified by validation experiments.The excellent correlation between predicted and experimental values confirmed the validity and practicability of this statistical optimum strategy.This study indicated the excellent ability of C.tropicalis Z-04 in degrading high-strength phenol.Optimal conditions obtained in this experiment laid a solid foundation for further use of this microorganism in the treatment of highstrength phenol effluents. | Jiangya Zhou Xiaojuan Yu Cong Ding Zhiping Wang Qianqian Zhou Hao Pao Weimin Ca | 2011 | Journal of Environmental Sciences2011，23，1： | 48 |
| 2 | Comparative studies on epithelial lesions at gastric cardia and pyloric antrum in subjects from a high incidence area for esophageal cancer in Henan,China显示文摘ComparativestudiesonepitheliallesionsatgastriccardiaandpyloricantruminsubjectsfromahighincidenceareaforesophagealcancerinHena... | GAO ShanShan1, ZHOU Qi1, LI YongXin1, BAI YongMin1, ZHENG ZuoYu1, ZOU JianXiang1, LIU Gang1, FAN ZongMin1, QI YiJun1, ZHAO Xin1 and WANG LiDong1,2Keywords esophageal neoplasms stomach neoplasms gastric ca | 1998 | World Journal of Gastroenterology1998，4，4： | 8 |
| 3 | 血管内皮生长因子受体3通过β抑制蛋白1调节内皮功能显示文摘受体信号转导对于维持血管内皮功能至关重要,其在动脉粥样硬化和肺动脉高压(pulmonary arterial hypertension,PAH)等血管疾病中出现失调。内皮功能相关受体信号包括血管内皮生长因子(vascular endothelial growth factor,VEGF)受体(VEGFR)和G蛋白耦联受体(G protein-coupled receptor,GPCR),激活特异的细胞内信号通路和反应。 | 刘青 叶鹏 Ma Z Yu YR Badea CT Kovacs JJ Xiong X Comhair S Piantadosi CA Rajagopal S | 2019 | 中华高血压杂志2019，27，1： | 5 |
| 4 | Effects of tumor necrosis factor alpha on host immune response in chronic persistent tuberculosis: possible role for limiting pathology显示文摘 | Mohan VP Scanga CA Yu K Scott HM Tanaka KE Tsang E Tsai MM Flynn JL Chan J | 2001 | Infect Immune2001，69，3： | 1 |
| 5 | Lipopolysaccharide-induced leptin release is neurally controlled 显示文摘 | Yu WH Srivastava VK | 2001 | Proc Natl Aced Sci USA2001，98，14： | 1 |
| 6 | Impaired myofibrillar energetics and oxidative injury during human atrial fibrillation显示文摘 | Mihm MJ Yu F Carnes CA | 2001 | Circulation2001，10，4： | 1 |
| 7 | Increased levels of totalP-Cresylsulphate and indoxyl sulphate are associated with coronaryartery disease in patients with diabetic nephropathy 显示文摘 | Chiu CA Lu LF Yu TH | 2010 | Rev DiabetStud2010，7，4： | 1 |
| 8 | Identification and gene organization of three novel members of the IL-1family on human chromosome 2显示文摘 | Busfield SJ Comrack CA Yu G | 2000 | Genomics2000，66，2： | 1 |
| 9 | The unstable burst fracture显示文摘 | M cA fee PC Yu anHA Lasda NA | 1982 | Spine(Phila Pa 1976)1982，7，： | 1 |
| 10 | Highly elevated ferritin levels and the diagnosis of hemophagooytic lymphohistiocytosis 显示文摘 | Allen CE Yu X Kozinetz CA | 2008 | Pediatr Blood Cancer2008，50，6： | 1 |
| 11 | Impaired fibrillar energetics an- doxidative injury during human atrial fibrillation显示文摘 | Mihm MJ Yu F Carnes CA | 2001 | Circulation2001，10，4： | 1 |
| 12 | Parathyroid hormone (1-34) enhances aggrecan synthesis via an insulin-like growth factor-1 pathway显示文摘 | Harvey AK Yu XP Frolik CA | 1999 | J Biol Chem1999，13，： | 1 |
| 13 | Changes before and after a policy to restrict antimicrobial usage in upper respiratory infections in Taiwan显示文摘 | Ho M Hsiung CA Yu HT | 2004 | Int J Antimicrob Agents2004，23，5： | 1 |
| 14 | Favorable clinical outcome of cervical cancers infected with human papilloma virus type 58 and related types显示文摘 | Lai HC Sun CA Yu MH | 1999 | Int J Cancer1999，84，6： | 1 |
| 15 | Estrogen-induced changes in IGF-I,Myb family and MAPkinase pathway genes in human uterine leiomyoma and normal uterine smooth muscle cell lines显示文摘 | Swartz1 CD Afshari CA Yu L | 2005 | Mol Hum Reprod2005，11，6： | 1 |
| 16 | Cutting edge: Systemic inhi- bition of angiogenesis underlies resistance to tumors during acute toxoplasmosis显示文摘 | Hunter CA Yu D Gee M | 2001 | J Immunol2001，166，10： | 1 |
| 17 | Impaired myofibriHar energetics and oxidative injury during human atrial fibril- lation显示文摘 | Mihm MJ Yu F Carnes CA | 2001 | Circulation2001，104，2： | 1 |
| 18 | Risk-based screening for latent tuberculosis infection显示文摘 | Haley CA Cain KP Yu C | | 0，，02： | 1 |
| 19 | Highly elevated ferritinlevels and the diagnosis of hemophagocytic lymphohistiocyto-sis显示文摘 | Allen CE Yu X Kozinetz CA | 2008 | Pediatr Blood Cancer2008，50，6： | 1 |
| 20 | Highly elevated ferritin levels and the diagnosis of hemophagocytic lymphohistiocytosis显示文摘 | Allen CE Yu X Kozinetz CA | | 0，，06： | 1 |
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