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| 1 | Retardant effect of dihydroartemisinin on ulcerative colitis in a JAK2/STAT3-dependent manner显示文摘Dihydroartemisinin(DHA)is a semi-synthetic derivative and the main active metabolite of artemisinin.The purpose of this study was to investigate the effect of DHA on the ulcerative colitis(UC)in both in vivo and in vitro models.Weight,survival rate,colon length,and Disease Activity Index score were used to evaluate the severity of colitis.Reverse transcription quantitative polymerase chain reaction and enzyme-linked immunosorbent assay were used to detect the expressions of cytokines interleukin(IL)-1,IL-1β,IL-4,IL-6,IL-10,IL-12,and tumor necrosis factor-α(TNF-α).The expressions of Janus kinase 2(JAK2)and signal transducer and activator of transcription 3(STAT3),and the phosphorylation of JAK2(p-JAK2)and STAT3(p-STAT3),were measured by western blot analysis.Western blot analysis and immunohistochemistry were used to detect the expressions of tight junction proteins.We found that the weights and colon lengths of mice in dextran sodium sulfate(DSS)+DHA group were significantly lower and longer than those in the DSS group,respectively.Compared with those in the DSS group,the expressions of IL-1β,IL-6,IL-17,and TNF-αin the DSS+DHA and DSS+5-aminosalicylic acid(5-ASA)groups were decreased,while the expressions of IL-4 and IL-10 were significantly upregulated.DHA largely increased the expressions of zonula occludens-1 and occludin.Western blot analysis and/or immunohistochemical staining analysis showed that the expressions of JAK2,STAT3,p-JAK2,and p-STAT3 in DSS+DHA and DSS+5-ASA groups were significantly lower than those in DSS group.DHA has a specific therapeutic effect on UC.The anti-inflammatory mechanism of DHA is related to the blockage of the JAK2/STAT3 signaling pathway.These findings provide evidence that DHA may be a useful drug and is expected to become a promising new treatment for human UC. | Mingrui Jiang Guangjun Zhong Yichao Zhu Liuhua Wang Yuzhe He Qiannan Sun Xiaoqing Wu Xiaolan You Sujun Gao Dong Tang Daorong Wang | 2021 | Acta Biochimica et Biophysica Sinica2021，53，9： | 6 |
| 2 | Surface Modification of Polyamide66 Fabric by Grafting with Vinyltrimethoxysilane显示文摘 | WANG Aijuan DUAN Yuzhe GU Xiaoyu ZHANG Sheng ZANG Wenhui | 2017 | Chemical Research in Chinese Universities2017，33，3： | 5 |
| 3 | How Can Chinese Farmers' Property Income Be Improved?A Population-Land Coupling Urbanization Mechanism显示文摘Balancing urban and rural development is an important political goal in China.The failure of rural land privatization has led to a low level of rural economic development and a vast property income gap between citizens and farmers.This paper illustrates the reasons for property income inequality from the perspective of the land tenure system and the dualistic household registration system.After evaluating the segmentation of the rural land market and the rigid nature of rural land assets,a population-land coupling urbanization mechanism is proposed.The paper argues that China s land property system has externalized a high degree of geospatial and social urban and rural intertwinement.Major reform of the rural land property rights system is required to correct the situation(further development of the social security system and stable urbanization)and to increase property income potential for farmers. | Yuzhe Wu Wendan Jiang Jiaojiao Luo Xiaoling Zhang Martin Skitmore | 2019 | China & World Economy2019，27，2： | 5 |
| 4 | Flavonoids and ROS Play Opposing Roles in Mediating Pollination in Ornamental Kale (Brassica oleracea var. acephala)显示文摘 | Xingguo Lan Jia Yang Kumar Abhinandan Yuzhe Nie Xiaoyu Li Yuhua Li Marcus A. Samuel | 2017 | Molecular Plant2017，10，10： | 5 |
| 5 | Nanosecond mid-infrared pulse generation via modulated thermal emissivity显示文摘We demonstrate the generation of nanosecond mid-infrared pulses via fast modulation of thermal emissivity enabled by the absorption of visible pump pulses in unpatterned silicon and gallium arsenide.The free-carrier dynamics in these materials result in nanosecond-scale modulation of thermal emissivity,which leads to nanosecond pulsed thermal emission.To our knowledge,the nanosecond thermal-emissivity modulation in this work is three orders of magnitude faster than what has been previously demonstrated.We also indirectly observed subnanosecond thermal pulses from hot carriers in semiconductors.The experiments are well described by our multiphysics model.Our method of converting visible pulses into the mid infrared using modulated emissivity obeys different scaling laws and can have significant wavelength tunability compared to approaches based on conventional nonlinearities. | Yuzhe Xiao Nicholas A.Charipar Jad Salman Alberto Pique Mikhail A.Kats | 2019 | Light(Science & Applications)2019，8，1： | 4 |
| 6 | Controlled growth and photoluminescence of highly oriented arrays of ZnO nanocones with different diameters显示文摘Large-scale oriented ZnO nanocone arrays were directly grown on zinc substrate through a hydro-thermal reaction of Zn foil with aqueous butylamine solution(3 mol/L) at 100-180 ℃ for 12 h.The syn-thesized products were characterized with X-ray diffraction,Raman spectrum,scanning electron mi-croscopy and transmission electron microscopy.The results showed that the ZnO nanocones were single crystalline with the wurtzite structure and grown along the [0001] direction.The diameter of nanocones is decreased with increasing the reaction temperature.A possible growth mechanism was also proposed to account for the formation of the ZnO nanocone arrays.The photoluminescence spectra of the ZnO nanocone arrays were studied at room temperature,two UV emission bands at 377 and 396 nm assigned to free exciton emission and exciton-exciton collision,respectively,and phonon replicas associated with 2-E2 phonon were observed in the PL spectra. | MA JunHu YANG HeQing SONG YuZhe LI Li XIE XiaoLi LIU RuiNi WANG LinFang | 2009 | Science China(Technological Sciences)2009，52，5： | 4 |
| 7 | Study on dynamic response of multi-body structure under explosive driving显示文摘In this study, a complex multi-body structure was proposed, and the mechanism for the dynamic response of the structure under explosive driving was investigated by using the Lagrange equations of the second kind. An initial value subject to explosion loading was analyzed to develop the theoretical model of the dynamic response, and the centroid trajectory of three different structural shapes was solved. To verify the accuracy of the theoretical model, numerical simulation via finite element analysis within LS-DYNA and a dynamic experiment were conducted, and the consistent dynamic response process of the multi-body structure was obtained. In addition, the dynamic response time of the multi-body structure under different explosion loading conditions was calculated by the theoretical model, numerical simulation, and experimental investigation. It was found that the increased opening charge mass reduces the dynamic response time. | ZHAO YuZhe MA TianBao LI Jian NING JianGuo | 2016 | Science China(Technological Sciences)2016，59，9： | 4 |
| 8 | A soft gripper of fast speed and low energy consumption显示文摘Grasping of complicated objects is an active research area which is developing fast throughout the years. Soft grippers can be an effective solution, since they are capable of holding workpieces of various shapes and interacting with unstructured environments effectively. Soft grippers generally consist of soft, flexible and compliant materials, which are able to conform to the shape of the object so that the gripper will not deform or bruise the soft object. Fast grasping of objects with various sizes and shapes remains a challenging task for soft grippers. In the present article, a soft gripper based on bi-stable dielectric elastomer actuator(DEA) inspired by the insect-catching ability of the Venus flytrap, is designed. This soft gripper can achieve good performances in grasping various objects by a simple actuation system. The gripper can switch from one stable state to another when subject to an impulse voltage of 0.04 s. The time duration for each grasping action is 0.17 s, and no continuous voltage is required for holding the gripped object. Thus, energy consumption can be achieved as low as 0.1386 J per grasping action. The mechanism of achieving bi-stable states is related to the duration of impulse voltage applied and the resonant frequency of the structure. The present study demonstrates that bi-stable dielectric elastomer actuators are capable of achieving fast speed for grasping with very low energy consumption, which is significant in the applications to soft grippers and biomimetic robots. | WANG YuZhe GUPTA Ujjaval PARULEKAR Nachiket ZHU Jian | 2019 | Science China(Technological Sciences)2019，62，1： | 4 |
| 9 | Elliptical model for surface topography prediction in five-axis flank milling显示文摘In five-axis flank milling operations,the intersecting surfaces of different cutting edges create roughness on the milled surfaces that cannot be ignored in situations with strict requirements,especially in aeronautical manufacturing.To focus on motion problems in milling operations,this paper presents a new model that utilizes elliptical paths as cutting edge trajectories on 3D surface topography machined by peripheral milling.First,the cutter parallel axis offset and location angle are considered,which change the location of the ellipse center and intersection point of the cutting edges.Then,through the proposed model,the predicted surface topography is obtained,and the factors that affect the development tendency of roughness are analyzed.Next,the effects of the cutter location position(CLP)geometric parameters,cutter parallel axis offset and curvature on the roughness are evaluated by a numerical simulation.Finally,machining tests are carried out to validate the model predictions,and the results show that the surface topography predictions correspond well with the experimental results. | Liping WANG Shuyi GE Hao SIa Liwen GUAN Feiyu DUAN Yuzhe LIU | 2020 | Chinese Journal of Aeronautics2020，33，4： | 3 |
| 10 | Evolvement behavior of microstructure and H_2O adsorption of lignite pyrolysis显示文摘The effect of pyrolysis on the microstructure and moisture adsorption of lignite was investigated with low field nuclear magnetic resonance spectroscopy. Changes in oxygen-containing groups were analyzed by Fourier transform infrared spectroscopy(FTIR), and H2 O adsorption mechanism on the surface of lignite pyrolysis was inferred. Two major changes in the pore structure of lignite char were observed as temperature increased in 105–200 °C and500–700 °C. Pyrolysis temperature is a significant factor in removing carboxyl and phenolic hydroxyl from lignite.Variation of ether bond content can be divided into three stages; the content initially increased, then decreased,and finally increased. The equilibrium adsorption ratio, content of oxygen-containing groups, and variation of pore volume below 700° were closely correlated with each other. The amount of adsorbed water on char pyrolyzed at700 °C increased. Moreover, the adsorption capacity of the lignite decreased, and the adsorption state changed. | Yingyue Teng Shijun Lian Quansheng Liu Yuzhe Liu Yinmin Song Runxia He Keduan Zhi | 2016 | Chinese Journal of Chemical Engineering2016，24，6： | 3 |
| 11 | Blue emitting CsPbBr3 perovskite quantum dot inks obtained from sustained release tablets显示文摘Blue emitting perovskite ink obtained from cesium lead halide quantum dots bearing chlorine(CsPbClxBr3-x,0 | Hewei Yang Yaqing Feng Zhiyu Tu Kuo Su Xiaozhi Fan Bingjie Liu Zhiping Shi Yuzhe Zhang Chenyang Zhao Bao Zhan | 2019 | Nano Research2019，12，12： | 2 |
| 12 | The impact of urbanization policy on land use change: A scenario analysis显示文摘 | Yuzhe Wu Xiaoling Zhang Liyin Shen | 2010 | Cities2010，，2： | 2 |
| 13 | Hydrogeochemical characterization and quality assessment of groundwater using self-organizing maps in the Hangjinqi gasfield area,Ordos Basin,NW China显示文摘Water resources are scarce in arid or semiarid areas,which not only limits economic development,but also threatens the survival of mankind.The local communities around the Hangjinqi gasfield depend on groundwater sources for water supply.A clear understanding of the groundwater hydrogeochemical characteristics and the groundwater quality and its seasonal cycle is invaluable and indispensable for groundwater protection and management.In this study,self-organizing maps were used in combination with the quantization and topographic errors and K-means clustering method to investigate groundwater chemistry datasets.The Piper and Gibbs diagrams and saturation index were systematically applied to investigate the hydrogeochemical characteristics of groundwater from both rainy and dry seasons.Further,the entropy-weighted theory was used to characterize groundwater quality and assess its seasonal variability and suitability for drinking purposes.Our hydrochemical groundwater dataset,consisting of 10 parameters measured during both dry and rainy seasons,was classified into 6 clusters,and the Piper diagram revealed three hydrochemical facies:Cl-Na type(clusters 1,2 and 3),mixed type(clusters 4 and 5),and HCO3-Ca type(cluster 6).The Gibbs diagram and saturation index suggested thatweathering of rock-forming mineralswere the primary process controlling groundwater chemical composition and validated the credibility and practicality of the clustering results.Two-thirds of 45 groundwater samples were categorized as excellent-or good-quality and were suitable as drinking water.Cluster changes within the same and different clusters from the dry season to the rainy season were detected in approximately 78%of the collected samples.The main factors affecting the groundwater quality were hydrogeochemical characteristics,and dry season groundwater quality was better than rainy season groundwater quality.Based on this work,such results can be used to investigate the seasonal variation of hydrogeochemical characteristics and assess water quality accurately in the others similar area. | Chu Wu Chen Fang Xiong Wu Ge Zhu Yuzhe Zhang | 2021 | Geoscience Frontiers2021，12，2： | 2 |
| 14 | Revealing a steroid receptor ligand as a unique PPARγ 3gonist显示文摘 | Shengchen Lin Ying Han Yuzhe Shi Hui Rong Songyang Zheng Shikan Jin Shu-Yong Lin Sheng-Cai Lin Yong Li | 2012 | Cell Research2012，22，4： | 2 |
| 15 | Negative cross-resistance of a pyrethroid-resistant Drosophila mutant to Phryma leptostachya-derived haedoxan A显示文摘Voltage-gated sodium channels are the primary target of pyrethroid insecticides.Mutations in sodium channel confer knockdown resistance(kdr)to pyrethroids in various arthropod pests.Haedoxan A(HA)is the major insecticidal component from Phryma leptostachya.It has been shown that HA alters electrical responses at the Drosophila neuromuscular junction and modifies the gating properties of cockroach sodium channels expressed in Xenopus oocytes.However,whether sodium channel mutations that confer pyrethroid resistance also affect the action of HA is unknown.In this study,we conducted bioassays using HA and permethrin in two Drosophila melanogaster strains:w^(1118),an insecticide-susceptible strain,and para^(tsl),a pyrethroid-resistant strain due to a I265N mutation in the sodium channel,and identified a new case of negative cross-resistance(NCR)between permethrin and HA.Both para^(tsl) larvae and adults were more resistant to permethrin,as expected.However,both para^(tsl) larvae and adults were more sensitive to HA compared to w^(1118).We confirmed that the I265N mutation reduced the sensitivity to permethrin of a Drosophila sodium channel variant,DmNa_(v)22,expressed in Xenopus oocytes.Interestingly,the I265N mutation also abolished the effect of HA on sodium channels.Further characterization showed that I265 on the sodium channels is critical for the action of both pyrethroids and HA on sodium channels,pointing to an overlapping mode of action between pyrethroids and HA on the sodium channel.Overall,our results suggest an I265N-independnt mechanism(s)in para^(tsl) flies that is responsible for the NCR between permethrin and HA at the whole insect level. | Xingtao Qie Yuzhe Du Ahmed A.A.Aioub Ke Dong Zhaonong Hu | 2022 | Insect Science2022，29，3： | 2 |
| 16 | Design and optimization of an integrated MEMS gas chamber with high transmissivity显示文摘Non-Dispersive InfraRed(NDIR)gas sensor is widely used for gas detection in collieries and the gas chemical industry,etc.The performance of the NDIR gas sensor depends on the volume,optical length and transmittance of the gas chamber.However,the existing gas sensor products have problems of large volume,high cost and incapable of integration,which need to develop towards the miniaturized sensor.This paper first presents the theoretical background of the NDIR gas sensor and the novel structure of a fully integrated infrared gas sensor and its micro-machined gas chamber structure.Then,the light structure and the gas flow of the gas chamber are optimized on Tracepro software and Ansys workbench,respectively,and the technological process for preparing the Micro-Electro-Mechanical System(MEMS)gas chamber is designed.Finally,we produce a gas chamber with a small volume and good transmissivity,which would be the most important part of producing the miniaturized NDIR gas sensor. | Yang Jing Cheng Yuhua Yuan Yupeng Li Xiaofei Zhang Zuwei Xu Ming Wang Dengpan Mu Jiangdong Mei Yong Zhang Yuzhe | 2021 | Digital Communications and Networks2021，7，1： | 2 |
| 17 | The bonding of ceramic and metal显示文摘 | Jin Yuzhe | 1993 | Transaction of Japan Welding Institute1993，11，3： | 1 |
| 18 | Green Strategy for Gaining Competitive Advantage in Housing Development:A China Study显示文摘 | Xiaoling Zhang Liyin Shen Yuzhe Wu | 2011 | Journal of Cleaner Production2011，19，： | 1 |
| 19 | Identifying risk factors of urban-rural conflict in urbanization: A case of China显示文摘 | Ann T.W. Yu Yuzhe Wu Bibo Zheng Xiaoling Zhang Liyin Shen | 2014 | Habitat International2014，，： | 1 |
| 20 | Gene cloning, expression, and localization of antigen 5 in the life cycle of Echinococcus granulosus显示文摘 | Yuzhe Li Hongxu Xu Jiajia Chen Wenjia Gan Weihua Wu Weiping Wu Xuchu Hu | 2012 | Parasitology Research2012，，6： | 1 |
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