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| 1 | Fatty liver is associated with an increased risk of diabetes and cardiovascular disease- Evidence from three different disease models: NAFLD, HCV and HIV显示文摘Fatty liver, which frequently coexists with necroinflammatory and fibrotic changes, may occur in the setting of nonalcoholic fatty liver disease(NAFLD) and chronic infections due to either hepatitis C virus(HCV) or human immunodeficiency virus(HIV). These three pathologic conditions are associated with an increased prevalence and incidence of cardiovascular disease(CVD) and type 2 diabetes(T2D). In this multidisciplinary clinical review, we aim to discuss the ever-expanding wealth of clinical and epidemiological evidence supporting a key role of fatty liver in the development of T2 D and CVD in patients with NAFLD and in those with HCV or HIV infections. For each of these three common diseases, the epidemiological features, pathophysiologic mechanisms and clinical implications of the presence of fatty liver in predicting the risk of incident T2 D and CVD are examined in depth. Collectively, the data discussed in this updated review, which follows an innovative comparative approach, further reinforce the conclusion that the presence of fatty/inflamed/fibrotic liver might be a shared important determinant for the development of T2 D and CVD in patients with NAFLD, HCV or HIV. This review may also open new avenues in the clinical and research arenas and paves the way for the planning of future, well-designed prospective and intervention studies. | Amedeo Lonardo Stefano Ballestri Giovanni Guaraldi Fabio Nascimbeni Dante Romagnoli Stefano Zona Giovanni Targher | 2016 | World Journal of Gastroenterology2016，22，44： | 4 |
| 2 | Slip locking in finite elements for composite beams with deformable shear connection显示文摘 | Dall'Asta A Alessandro Zona | 2004 | Finite Elenents is Analysis and Design2004，40，4： | 1 |
| 3 | Cross-linking agents, degree of crosslinkage and calcifiability in bioprosthetic heart valves显示文摘 | Baker M Zona D | 1990 | Trans Soc Biomater1990，13，： | 1 |
| 4 | Detection of bid rigging in procurement auctions显示文摘 | Porter R H Zona J D | 1993 | Journal of Political Economy1993，，： | 1 |
| 5 | Levetiracetam does not modulate neuronal voltage-gated Na+and T-type Ca2+currents显示文摘 | Zona C Niespodziany I Marchetti C | 2001 | Seizure2001，10，： | 1 |
| 6 | Detection of bid rigging in procurement auetion显示文摘 | Porter R H Zona J D | 1993 | Journal of Political Economy1993，101，： | 1 |
| 7 | Detoxification of aqueous chlorophenol solutions by ionizing radiation 显示文摘 | Zona R Schmid S Solar S | 1999 | Water Research1999，33，5： | 1 |
| 8 | Dimensions of CEO-board relations 显示文摘 | Boyd B K Haynes K T Zona F | 2011 | Journal of Management Studies2011，48，8： | 1 |
| 9 | Wet-chem- istry method for the separation of no-carrier-added At-211/Po 211g from Bi-209 target irradiated by alpha-beam in cyclotron 显示文摘 | Zona C Bonardi ML Groppi F | 2008 | J Radioanal Nucl Chem2008，276，3： | 1 |
| 10 | An Analysis of Asymmetric Demand Response to Price Changes: The Case of Local Telephone Calls 显示文摘 | BidweU M O Wang B X Zona J D | 1995 | Journal of Regulatory Economics1995，，8： | 1 |
| 11 | Wet-chem-istry method for the separation of no-carrier-added 211 At/211 Po from 209 Bi target irradiated by alpha-beam in cyclotron显示文摘 | Zona C Bonardi ML Groppi F | 2008 | J Radioanal and Nucl Chem2008，276，3： | 1 |
| 12 | Levetiracetam does not Modulate Neuronal Voltage-gated Na+ and T-type Ca2+ currents显示文摘 | Zona C Niespodzinay I Marcheth C | 2001 | Seizure(S1059-1311)2001，10，4： | 1 |
| 13 | Levetiracetam does not modulate neuronal voltage-gated Na and T-type Ca currents 显示文摘 | Zona C Niespodziany I Marchetti C | 2001 | Seizure2001，10，4： | 1 |
| 14 | Detection of bid rigging in procurement auctions显示文摘 | Porter R H Zona J D | 1993 | Journal of Political Economy1993，，： | 1 |
| 15 | Non-linear analysis of composite beams by a displacement approach 显示文摘 | DALL'ASTA A ZONA A | 2002 | Computers and Structures2002，80，27282930： | 1 |
| 16 | Nonlinear seismic response analysis of steel-concrete composite frames 显示文摘 | Zona A Barbato M Conte J P | 2008 | Journal of Structural Engineering ASCE2008，134，6： | 1 |
| 17 | Levetiracetam does not modulate neuronal voltage-gated Na^+ and T-type Ca^2+ currents显示文摘 | ZONA C NIESPODZIANY I MARCHETYI C | 2001 | Seizure2001，10，4： | 1 |
| 18 | Three-field mixed formulation for the non-linear analysis of composite beams with deformable shear connection 显示文摘 | DALL'ASTA A ZONA A | 2004 | Finite Elements in Analysis and Design2004，40，4： | 1 |
| 19 | Laparoscopic cholecystectomy with Harmonic scalpel显示文摘 | Gelmini R Franzoni C Zona S | 2010 | SLS2010，14，1： | 1 |
| 20 | Levitiracetam does not modulate neuronal voltagegated Na^+ and T-type Ca^2+ currents 显示文摘 | Zona C Niespodziany I Marchetti C Klitgaard H Bernardi G Margineanu DG | 2001 | Seizure2001，10，4： | 1 |
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