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    题名 作者 年代 出处 被引量
1REVIEW ON RESEARCH AND DEVELOPMENT OF MAGNESIUM ALLOYS显示文摘镁合金的当前的研究和发展被总结。镁合金的几个方面被描述:演员组 Mg 合金,做 Mg 合金,并且小说处理。这些题目个别地被讨论,为进一步的学习的建议在最后的节被列出。Z. Yang J.P. Li J.X. Zhang G.W. Lorimer J. Robson 2008Acta Metallurgica Sinica(English Letters)2008,21,5:93
2Selective blockade of NF-kappa B by novel mutated I kappa B alpha suppresses CD3/CD28-induced activation of memory CD4(+) T cells in asthma显示文摘Background:Nuclear factor kappa B(NF-kappa B) overactivation plays a crucial role in T-helper 2 (Th2)-biased allergic airway inflammation by increased activation and decreased apoptosis of CD4(+) T cells. We have shown that targeted NF-kappa B suppression in dendritic cells by adenoviral gene transfer of a novel mutated inhibitor of NF-kappa B(I kappa B alpha) (AdI kappa B alpha M) contributes to T-cell tolerance, but the immunosuppressive action of AdI kappa B alpha M on memory(CD45RO(+)) CD4(+) T cells remains enigmatic. Methods:CD45RO(+) T cells from Dermatophagoides farinaei-sensitized asthmatic patients, untransfected or transfected with AdI kappa B alpha M or AdLacZ(beta-galactosidase) for 24 h, were stimulated with anti-CD3(1.0 mu g/ml) plus anti-CD28(0.5 mu g/ml) monoclonal antibody for an additional 24 h. I kappa B alpha M transgene expression and NF-kappa B activation were detected by polymerase chain reaction(PCR), reverse transcription-PCR(RT-PCR), Western blot analysis, and electrophoretic mobility shift assay. Phenotype and apoptosis were measured by flow cytometry, annexin V binding, and terminal deoxyribonucleotidyl transferase-mediated dUTP nick end labeling analyses. Cytokine production and cell proliferation were determined using enzyme-linked immunosorbent assay andH-3 thymidine incorporation. Results:A unique 801-bp I kappa B alpha M cDNA and a dose-dependent increase in I kappa B alpha M transgene expression were observed in AdI kappa B alpha M-transfected CD45RO(+) T cells. Significantly, AdI kappa B alpha M inhibited CD3/CD28-mediated NF-kappa B activation in CD45RO(+) T cells, leading to evident apoptosis, reduction of eotaxin, RANTES, Th1 interferon (IFN)-gamma and interleukin (IL)-2, and Th2 (IL-4, IL-5, and IL-13 despite a slight decrease in IL-10) cytokines and secondary proliferative response. AdI kappa B alpha M also upregulated cytotoxic T lymphocyte-associated antigen 4(CTLA-4) and downregulated CD69 besides no change in CD28. Conclusion:I kappa B alpha M might be beneficial to augment memory CD4(+) T-cell tolerance through modulating B7-CD28/CTLA-4 co-stimulatory pathways and NF-kappa B-dependent cytokine profiles in allergic inflammatory diseases including asthma.Zhou,L. F. Zhang,M. S. Hu,A. H. Zhu Z. Yin,K. S. 2008南京医科大学学报(自然科学版)2008,28,6:40
3Intracellular tat of human immunodeficiency virus type 1 activates lytic cycle replication of Kaposi's sarcoma-associated herpesvirus. Role of JAK/STAT signaling显示文摘Zeng, Y. Zhang, X. H. Huang, Z. Cheng, L. Yao, S. H. Qin, D. Chen, X. Y. Tang, Q. Lv, Z. G. Zhang, L. Lu, C. 2007南京医科大学学报(自然科学版)2007,27,5:31
4EFFECTS OF SPECIFIED BLANK SIZE ON BODY WRINKLING DURING HYDRODYNAMIC DEEP DRAWING OF TAPERED RECTANGULAR BOX显示文摘In this paper, the forming features of tapered rectangular box during hydrodynamic deep drawing are studied by means of FEM.The effect rules of square blank corner corner amount on body wrinkling are recognized and corresponding methods are discussed. At last, the results of FEM are verified by experi- ment.L. H. Lang, D. C. Kang, S. H. Zhang, Z. R. Wang, S. J. Yuan, K. B. Nielsen and J. Dancket 1) Department of Materials Engineering, Harbin Institute of Technology, Harbin 150001, China 2) Aalberg University, Denmark 2000Acta Metallurgica Sinica(English Letters)2000,13,2:21
5Cadmium Accumulation and Translocation in Two Jerusalem Artichoke(Helianthus tuberosus L.) Cultivars显示文摘Jerusalem artichoke(Helianthus tuberosus L.) not just can be used for bioethanol production but may be potentially used in phytoremediation for the removal of heavy metal pollutants.Two Jerusalem artichoke cultivars,N2 and N5,were subjected to six cadmium(Cd) concentrations(0,5,25,50,100 and 200 mg L1) to investigate Cd tolerance and accumulation.After 21 days of growth,the effects of Cd on growth,chlorophyll content,net photosynthetic rate,intercellular CO2 concentration and malondialdehyde content were evaluated.Most growth parameters were reduced under Cd stress.The two Jerusalem artichoke cultivars had relatively high Cd tolerance and accumulation capacity(> 100 mg kg1),with N5 being more tolerant and having higher Cd accumulation than N2.Roots accumulated more Cd than stems and leaves.The bioconcentration factors(far higher than 1) and translocation factors(lower than 1) decreased with an increase in Cd applied.The results suggested that Jerusalem artichoke could be grown at relatively high Cd loads,and N5 could be an excellent candidate for phytoremediation of Cd-contaminated soils.CHEN Liang LONG Xiao-Hua ZHANG Zhen-Hua ZHENG Xiao-Tao Z. RENGEL LIU Zhao-Pu 2011Pedosphere2011,21,5:19
6EFFECT OF Zr ADDITION TO Ti-KILLED STEEL ON INCLUSION FORMATION AND MICROSTRUCTURAL EVOLUTION IN WELDING INDUCED COARSE-GRAINED HEAT AFFECTED ZONE显示文摘化学部件和忍受 Ti 包括的尺寸分发上的锆的效果,赞成了导致的、纹理粗糙的热影响了的焊接的谷物精炼地区(CGHAZ ) 与在杀死 Ti 的钢提高了影响坚韧,它基于试验性的观察和热力学的计算被检验。它显示包括的化学成分逐渐地从 Ti-O 氧化物变化了到 Ti-O+Zr-O 复合氧化物和 ZrO2 氧化物的一个单个阶段,作为内容从零增加了到 0.0100% 的 Zr。 Zr 的踪迹(0.0030%0.0080%,在液体钢取决于氧内容)因为 ZrO2 氧化物的更大的特定的密度,为 Ti 氧化物提供了大量起核心作用的核心,并且生产了有利的包括的小尺寸分布因为有在 CGHAZ 的高成核率的针状的铁酸盐转变,和针状的铁酸盐的大量的部分在 CGHAZ 被获得,与提高的影响坚韧。否则, Zr (0.0100%) 的一个高内容生产了单个阶段 ZrO2,它是无力的起核心作用由铁酸盐方面板组成的针状的铁酸盐和谷物边界铁酸盐在 CGHAZ 发展了。试验性的结果被热力学的计算证实。F. Chai C.F. Yang H. Su Y.Q. Zhang Z. Xu Y.H. Yang 2008Acta Metallurgica Sinica(English Letters)2008,21,3:18
7TiZr-base Bulk Metallic Glass with over 50 mm in Diameter显示文摘Low-cost TiZr-base bulk metallic glasses(BMGs)(Ti36.1Zr33.2Ni5.8Be24.9)100-xCux(x=5,7 and 9) with a maximum size of over 50 mm in diameter were developed by optimizing the alloy composition.The idea is initiated by selecting a particular microstructure comprising primary β-Ti dendrite and amorphous phase.Afterwards,based on this composition of amorphous phase,a class of TiZr-base bulk metallic glasses was designed step by step to reach the optimum composition range.The glass transition temperature(Tg),initial crystallization temperature(Tx) and width of supercooled region(△T) of(Ti36.1Zr33.2Ni5.8Be24.9)91Cu9 BMG are 611,655 and 44 K,respectively.The(Ti36.1Zr33.2Ni5.8Be24.9)91Cu9 BMG exhibits low density of 5.541 g·cm-3 and high compressive fracture strength of 1800 MPa,which promises the potential application as structural materials.M. Q. Tang H.F. Zhang Z. W. Zhu H.M. Fu A.M. Wang H. Li Z.Q. Hu 2010Journal of Materials Science & Technology2010,26,6:17
8CORROSION MONITORING OF LY12 IN SODIUM CHLORIDE SOLUTION WITH ELECTROCHEMICAL NOISE TECHNIQUE显示文摘Spontaneous electrochemical noise (EN) can be a rich source of information concerning the processes simultaneously occurring on a corroding interface. But the noise signal is often difficult to be analyzed due to the complicated nature of the specific systems being investigated. In this paper the potential noise fluctuations during the bee corrosion of commercial aluminum alloy LY12 in sodium chloride solution was recorded and analyzed with different techniques. The typical results showed that the fractal dimension (Dn) obtained from spectral power density (SPD) is mainly directly proportional to the intensity of pitting corrosion and to the value of pitting parameter (SE) derived hem dimensional analysis, while the fractal dimension (DE) obtained from EIS is mainly related to the uniform corrosion.J.Q. Zhang, Z. Zhang, J.M. Wang, H.B. Shao and C.N. Cao (Department of Chemistry, Zhejiang University , Hangzhou 310027, China) (State Key Laboratory for Corrosion and Protection of Metals, Institute of Metal Research, The Chinese Academy of Sciences, She 2001Acta Metallurgica Sinica(English Letters)2001,14,2:14
9Contamination by Organochlorine Pesticides in the Estuaries of Southeast China显示文摘Persistent organic pollutants(POPs) such as organochlorine pesticides are of global concern due to their widespread occurrence and persistence. This paper reports recent research studying the distribution and fate of organochlorine pesticides in the Jiulong River, the Minjiang River and the Pearl River estuaries in Southeast China. Eighteen organochlorine pesticides were extracted from water, pore water and sediment samples, followed by analysis by GC ECD. The results showed that the contamination levels were similar in these three estuaries. The levels of the total organochlorine pesticides in porewater were significantly higher than those in surface water, due to the high affinity of these hydrophobic compounds for sediment phase. Among the hexachlorocyclohexane(HCH) compounds, β HCH was found to be the most important isomer. The analysis of 1,1,1 trichloro 2,2 bis chlorophenyl ethane(DDT) and its metabolites showed that 1,1 dichloro 2[ o chlorophenyl] 2[ p chlorophenyl] ethylene(DDE) was dominant in the group.Z. L. Zhang 1,2 , H. S. Hong 2, J. L. Zhou 3,** , M. H. Dai 2, K. Maskaouib 2 and W. Q. Chen 2 1. Department of Environmental Science and Engineering, Tsinghua POPs Research Centre, Tsinghua University, Beijing 100084, China 2. Key Laborator 2002Chemical Research in Chinese Universities2002,18,2:13
10Voluntary exercise-induced neurogenesis in the postischemic dentate gyrus is associated with spatial memory recovery from stroke显示文摘Luo, C. X. Jiang, J. Zhou, Q. G. Zhu, X. J. Wang, W. Zhang, Z. J. Han, X. Zhu, D. Y. 2007南京医科大学学报(自然科学版)2007,27,10:13
11The relative immunogenicity of DNA vaccines delivered by the intramuscular needle injection, electroporation and gene gun methods显示文摘Wang, S. X. 2008南京医科大学学报(自然科学版)2008,28,9:12
12Polymorphisms of MTHFD,plasma homocysteine levels, and risk of gastric cancer in ahigh-risk Chinese population显示文摘Purpose:Accumulative evidence suggests that folate has a protective effect on gastric cancer. The methylenetetrahyd-rofolate dlehydrogenase(MTHFD) plays an important role in folate and homocysteine metabolisms, and polymorphisms of MTHFD may result in disturbance of the folate-mediated homocysteine pathway. The aim of this study is to test the hypothesis that genetic variants of MTHFD and plasma homocysteine levels are associated with risk of gastric cancer and modulated by genotypes of methylenetetrahydrofolate reductase(MTHFR). Experimental Design: We genotyped G1958A and T401C in MTHFD and C677T in MTHFR and detected total plasma homocysteine(tHcy) levels in a case-control study of 589 gastric cancer cases and 635 cancer-free controls in a high-risk Chinese population. Results:The variant genotypes of MTHFD 1958AA and 401CC were associated with a significantly increased risk of gastric canceradjusted odds ratio(OR), 2.05; 95% confidence interval(95% CI),1.34-3.13 for 1958AA; adjusted OR,1.43; 95% CI,1.14-1.80 for 401CC compared with 1958GG/GA and 401TT/TC genotypes, respectively. Both of the effects were more evident in the subjects carrying MTHFR 677CT/TT genotypes. The average tHcy level was significantly higher in gastric cancer cases than in controls(P < 0.01), and the upper quartile of tHcy (> 13.6 mu mol/L) was associated with an 82% significantly increased risk of gastric cancer, compared with the lowest quartile of tHcy(<= 8.0 pmol/L;adjusted OR,1.82; 95% CI,1.20-2.75). Conclusions:The strong associations between MTHFD variants and the plasma tHcy levels and gastric cancer risk suggest, for the first time, a possible gene-environment interaction between genetic variants of folate-metabolizing genes and high tHcy levels in gastric carcinogenesis.Wang, L. N Ke, Q Chen, W. S Wang, J. M Tan, Y. F Zhou, Y Hua, Z. L Ding, W. L Niu, J. Y Shen, J Zhang, Z. F Wang, X. R Xu, Y. H Shen, H. B Yi Xing 2007南京医科大学学报(自然科学版)2007,27,7:10
13Signaling pathways for germ cell death in adult cynomolgus monkeys(Macaca fascicularis) induced by mild testicular hyperthermia and exol enous testosterone treatment显示文摘Jia, Y. Hikim, A.P.S. Lue,Y.H. Swerdloff, R.S. Vera,Y. Zhang,X. S. Hu, Z. Y. Li, Y. C. Liu, Y. X. Wang, C 2007南京医科大学学报(自然科学版)2007,27,10:10
14Optimisation of cultivation conditions of a mutant of Trichosporon laibachii CBS 5791 for enantioselective resolution of ketoprofen ester显示文摘Zhang, Y. Y. Liu, J. H. Qiu, L. H. Shi, Y. J. Su, Z. L. Xia, Y. M. Li, F. M. 2007中国生物学文摘2007,21,2:9
15Proteomic-based identification of maternal proteins in mature mouse oocytes显示文摘Zhang, P. Ni, X.J. Guo, Y. Guo, X. J. Wang, Y. F. Zhou, Z. M. Huo, R. Sha, J. H. 2009南京医科大学学报(自然科学版)2009,29,11:8
16CdSe Quantum Dot-Sensitized Au/TiO2 Hybrid Mesoporous Films and Their Enhanced Photoelectrochemical Performance显示文摘敏化的 Au/TiO2 混合 mesoporous 拍摄的新奇 CdSe 量点(QD ) 为 photoelectrochemical (PEC ) 被设计了,制作,并且评估应用。Au/TiO2 混合结构被 Au 和 TiO2 nanoparticles (NP ) 的汇编做。一个化学洗澡免职方法被使用有或没有嵌入的 Au NP 在 TiO2 NP 电影上扔 CdSe QD。我们与 Au NP 为这部电影在光电流观察了重要改进,在全部光谱我们学习了的区域(350600 nm ) 。Incident-photon-to-current 效率(IPCE ) 数据揭示了 50% 的平均改进,并且改进在短波长是更重要的。这实质地改进的 PEC 表演尝试性地由于由 Au NP 散布的光被归因于 CdSe QD 的增加的轻吸收。没有 QD 促进感受性,有趣地, Au NP 熄灭了 TiO2 电影的光电流,由于电子在由 Au NP 散布的光上套住的优势。结果建议金属 NP 为在 PEC 房间改进 photoresponse 是潜在地有用的,可能,在象太阳能电池那样的另外的设备,基于敏化 QD 的金属氧化物, nanostructured 拍摄。这个工作表明 NP 能作为散布中心的光服务的那金属,除作为 photo-sensitizers 和电子陷井工作以外。在一部特别 nanocomposite 电影的金属 NP 的功能强烈依赖于他们的结构和形态学。Liping Liu Gongming Wang Yat Li Yadong Li Jin Z. Zhang 2011Nano Research2011,4,3:8
17Variant alleles of TGFB1 and TGFBR2 are associated with a decreased risk of gastric cancer in a Chinese population显示文摘Jin, G. F. Wang, L. N. Chen, W. S. Hu, Z. B. Zhou, Y. Tan, Y. F. Wang, J. M. Hua, Z. L. Ding, W. L. Shen, J. Zhang, Z. F. Wang, X. R. Xul, Y. C. Shen, H. B. 2007南京医科大学学报(自然科学版)2007,27,5:7
18ELECTROCHEMICAL NOISE ANALYSIS OF PURE ALUMINUM IN SODIUM CHLORIDE SOLUTION WITH WAVELET TRANSFORM TECHNIQUE显示文摘Wavelet transforms (WT) are proposed as an alternative tool to overcome the limitations of Fourier transforms (FFT) in the analysis of electrochemical noise (EN) data. The most relevant feature of this method of analysis is its capability of decomposing electrochemical noise records into different sets of wavelet coefficients, which contain information about the time scale characteristic of the associated corrosion event. In this context, the potential noise fluctuations during the free corrosion of pure aluminum in sodium chloride solution was recorded and analyzed with wavelet transform technique. The typical results showed that the EN signal is composed of distinct type of events, which can be classified according to their scales, i.e. their time constants. Meanwhile, the energy distribution plot (EDP) can be used as 'fingerprints' of EN signals and can be very useful for analyzing EN data in the future.Z. Zhang, Q.D. Zhong, J.Q. Zhang, Y.L. Cheng, F.H. Cao, J.M. and C.N. CaoDepartment of Chemistry, Zhejiang University, Hangzhou 310027, ChinaElectrochemical Research Group, Shanghai University of Electric Power, Shanghai 200090, ChinaState Key Laboratory 2002Acta Metallurgica Sinica(English Letters)2002,15,3:7
19Genetic variants in the death receptor 4 gene contribute to susceptibility to bladder cancer显示文摘Wang, M. L. Wang, M. M. Cheng, G. Zhang, Z. Z. Fu, G. B. Zhang, Z. D. 2009南京医科大学学报(自然科学版)2009,29,4:6
20Nickel-coated silicon photocathode for water splitting in alkaline electrolytes显示文摘切开的 Photoelectrochemical (PEC ) 水是一条有希望的途径收获并且存储太阳能[1 ] 。硅广泛地由于它匹配太阳的光谱的合适的乐队差距(1.12 eV ) 为 PEC photoelectrodes 被调查了[2 ] 。这里,我们调查作为催化剂两个都采用镍并且第一次在基本电解质为 photoelectrochemical 氢进化保护 p 类型硅光阴极的层。硅光阴极被在 5 nm Ni 跟随的 p 类型硅晶片上扔 15 nm Ti 做。光阴极在碱的答案(1 M KOH ) 负担得起 0.3 V 对可逆的氢电极(RHE ) 的一个发作潜力。Ni/Ti/p-Si 光阴极的稳定性在 KOH 在 12 h 上看了 100 mV 腐烂,但是稳定性显著地被改进光阴极什么时候在钾硼酸盐缓冲区答案被操作(pH 9.5 ) 。电极表面被发现在 10 妈 / 厘米的经常的当前的密度在连续操作的 12 h 以后仍然保持未经触动 < 啜 class= “ a-plus-plus ” > 在钾硼酸盐缓冲区的 2 ,建议 Ni 负担得起 Si 的好保护在硼酸盐缓冲区基于光阴极。Ju Feng Ming Gong Michael J. Kenney Justin Z. Wu Bo Zhang Yanguang Li Hongjie Dai 2015Nano Research2015,8,5:6
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