|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | ,Cytogenetic investigation in a Brazilian population living in an area of high natural radioactivity显示文摘 | BarcinskiMA Do Céu Abreu M De Almeida JC | 1975 | Am J Hum Genet1975，27，6： | 1 |
| 3 | Mental health among perimenopausal women attending a menopause clinic:possible association with premenstrual syndrome?显示文摘 | Novaes C Almeida OP de Melo NR | 1998 | Climacteric1998，，4： | 1 |
| 4 | Study of the quality of life in people with traumatic spinal cord injury显示文摘 | VALL J BRAGA V A DE ALMEIDA P C | 2006 | Arquivos de Neuro-Psiquiatria2006，64，2： | 1 |
| 5 | Study on high performance roller compacted concrete显示文摘 | BETTENCOURT RIBEIRO A C DE ALMEIDA I R | 2000 | Materials and Structures2000，33，6： | 1 |
| 6 | Effect of soil moisture and fertilization on Perola pineapple in Coastal Tableland areas of Brazil 显示文摘 | Souza L F D de Almeida O A Caldas R C | 2002 | Tropical Agriculture2002，79，2： | 1 |
| 7 | Physical Characterization and Compression Tests of One Leaf Stone Masonry Walls 显示文摘 | Almeida C Guedes J P Ar~de A | 2012 | Construction and Building Materials2012，30，： | 1 |
| 8 | Immune dysfunction in caveolin-1 null mice following infection with Trypanosomacruzi (Tulahuen strain)显示文摘 | Medina FA Cohen AW de Almeida C J | 2007 | Microbes Infect2007，，： | 1 |
| 9 | Zona pellucida birefringence score and meiotic spindle visualization in relation to embryo development and ICSI outcomes显示文摘 | Madaschi C Aoki T de Almeida Ferreira Braga DP | 2009 | Re-prod Biomed Online2009，18，5： | 1 |
| 10 | Differences in pain expression between male and femaie new- born infants显示文摘 | Guinsburg R de Aranjo Peres C Branco de Almeida MF | 2000 | Pain2000，85，12： | 1 |
| 11 | Dredging and disposal of fine sediments in the state of Rio de Janeiro, Brazil显示文摘 | BARBOSA M C DE SOUZA SOARES DE ALMEIDA l~I | 2001 | Journal of Hazardous Materials2001，85，12： | 1 |
| 12 | Fuzzy Kohonen Clustering Networks for Interval Data显示文摘 | de Almeida C W D de Souza R M C R Candeias A L B | | 0，，01： | 1 |
| 13 | Bacterial translocation:overview of mechanisms and clinical impact显示文摘 | Balzan S de Almeida Quadros C | 2007 | J Gastroenterol Hepatol2007，22，4： | 1 |
| 14 | Bacterial translocation:over view of mechanicsms and clinical impact显示文摘 | Balzan S de Almeida Quadros C de Cleva R | 2007 | J Gastroenterol Hepatol2007，22，4： | 1 |
| 15 | Bacterial translocation:overview of mechanisms and clinical impact显示文摘 | Balzan S de Almeida Quadros C de Cleva R etal | 2007 | J Gastroenterol Hepatol2007，22，4： | 1 |
| 16 | A new and distinctive male-sterile, female-fertile desynaptic mutant in soybean (Glycine max)显示文摘 | BIONE N C PAGLIARINI M S DE ALMEIDA L A | 2002 | Hereditas2002，136，2： | 1 |
| 17 | Quantification of RecA protein in Deinococcus radiodurans reveals involvement of RecA, but not LexA, in its regulation显示文摘 | Bonacossa de Almeida C Coste G Sommer S Bailone A | 2002 | Molecular Genetics and Genomics2002，268，1： | 1 |
| 18 | Flavonol monoglycosides isolated from the antiviral fractions of Persea americana (Lauraceae) leaf infusion 显示文摘 | De Almeida A P Miranda M M F S Simoni I C | 1998 | PhytotherRes1998，12，8： | 1 |
| 19 | Group decision-making for leakage management strategy of water network显示文摘 | Morais D C de Almeida A T | 2007 | Resour Conserva Recycl2007，52，2： | 1 |
| 20 | Puberty does not induce serum antisperm surface antibodies in patients with previously operated eryptorchidism 显示文摘 | Mirilas P Mamoulakis C de Almeida M | 2003 | J Urol2003，170，61： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员