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| 1 | Surgical treatment of gastric cancer: 15-year follow-up results of the randomised nationwide Dutch D1D2 trial显示文摘 | Ilfet Songun Hein Putter Elma Meershoek-Klein Kranenbarg Mitsuru Sasako Cornelis JH van de Velde | 2010 | Lancet Oncology2010，，5： | 20 |
| 2 | 25-羟维生素D和甲状旁腺激素与高血压的相关性显示文摘有研究证实,维生素D缺乏和甲状旁腺激素(PTH)过高与高血压的发生密切相关。维生素D缺乏不仅可以影响肾素血管紧张素系统及PTH水平,而且可以直接参与血管炎性反应,影响高血压的发生发展。PTH可以通过促进血管炎性反应及血管钙化等参与高血压的进展。目前还没有前瞻性研究同时评估维生素D和PTH水平与高血压发病的关系。该研究分析多民族动脉粥样硬化研究的前瞻性数据,发现低水平25羟维生素D[25(OH)D]和高水平PTH与高血压发病相关,特别是在肥胖人群中。但在校正混杂因素后,25(OH)D水平与高血压发病的相关性无统计学意义,而PTH水平与高血压发病仍然相关。鉴于维生素D缺乏和PTH过量在人群中是普遍现象,该研究对于更好地了解高血压发病机制,在人群中开展高血压预防工作有重要意义。 | van Ballegooijen AJ Kestenbaum B Sachs MC de Boer IH Siscovick DS Hoofnagle AN Ix JH Visser M Brouwer IA 练桂丽 叶鹏 | 2014 | 中华高血压杂志2014，22，6： | 10 |
| 3 | Near-infrared fluorescence sentinel lymph node detection in gastric cancer: A pilot study显示文摘AIM: To investigate feasibility and accuracy of nearinfrared fluorescence imaging using indocyanine green: nanocolloid for sentinel lymph node(SLN) detection in gastric cancer.METHODS: A prospective, single-institution, phaseI feasibility trial was conducted. Patients suffering from gastric cancer and planned for gastrectomy were included. During surgery, a subserosal injection of 1.6 m L ICG:Nanocoll was administered around the tumor. NIR fluorescence imaging of the abdominal cavity was performed using the Mini-FLARE? NIR fluorescence imaging system. Lymphatic pathways and SLNs were visualized. Of every detected SLN, the corresponding lymph node station, signal-to-background ratio and histopathological diagnosis was determined. Patients underwent standard-of-care gastrectomy. Detected SLNs outside the standard dissection planes were also resected and evaluated.RESULTS: Twenty-six patients were enrolled. Four patients were excluded because distant metastases were found during surgery or due to technical failure of the injection. In 21 of the remaining 22 patients, at least 1 SLN was detected by NIR Fluorescence imaging(mean 3.1 SLNs; range 1-6). In 8 of the 21 patients, tumor-positive LNs were found. Overall accuracy of the technique was 90%(70%-99%; 95%CI), which decreased by higher p T-stage(100%, 100%, 100%, 90%, 0% for respectively Tx, T1, T2, T3, T4 tumors). All NIR-negative SLNs were completely effaced by tumor. Mean fluorescence signal-to-background ratio of SLNs was 4.4(range 1.4-19.8). In 8 of the 21 patients, SLNs outside the standard resection plane were identified, that contained malignant cells in 2 patients.CONCLUSION: This study shows successful use of ICG:Nanocoll as lymphatic tracer for SLN detection in gastric cancer. Moreover, tumor-containing LNs outside the standard dissection planes were identified. | Quirijn RJG Tummers Leonora SF Boogerd Wobbe O de Steur Floris PR Verbeek Martin C Boonstra Henricus JM Handgraaf John V Frangioni Cornelis JH van de Velde Henk H Hartgrink Alexander L Vahrmeijer | 2016 | World Journal of Gastroenterology2016，22，13： | 9 |
| 4 | Near-infrared fluorescence imaging of a solitary fibrous tumor of the pancreas using methylene blue显示文摘A 67-year-old female presented with unexplained abdominal pain. A contrast-enhanced computed tomography scan of the abdomen incidentally revealed a mass in the uncinate process of the pancreas. This mass was resected and based on histopathological findings, diagnosed as a solitary fibrous tumor (SFT) of the pancreas. A SFT is an extremely rare benign mesenchymal tumor that in 65% of cases affects the visceral pleura but can also affect extra-pleural sites. The intraoperative demarcation of pancreatic tumors, such as SFTs, can bechallenging. In this report, the first clear intraoperative identification of a SFT of the pancreas in a human was shown using near-infrared fluorescence and methylene blue. | Joost R van der Vorst Alexander L Vahrmeijer Merlijn Hutteman Tjalling Bosse Vincent THBM Smit Cornelis JH van de Velde John V Frangioni Bert A Bonsing | 2012 | World Journal of Gastrointestinal Surgery2012，4，7： | 7 |
| 5 | 早发性先兆子痫,迟发性先兆子痫和妊娠高血压后的心血管疾病危险因素显示文摘研究表明,有妊娠高血压病史的妇女心血管疾病(cardiovasculardisease,CVD)终生风险增加。这种风险与妊娠相关高血压疾病的严重程度及发病孕周有关。然而,cVD危险因素的差异是否在产后心血管筛查时就已经存在尚不清楚。研究人员将妊娠期高血压疾病患者分为3个亚组,分析CVD危险因素的产后差异。 | 刘莉 叶鹏 Veerbeek JH Hermes W Breimer AY van Rijn BB Koenen SV Mol BW Franx A de Groot CJ Koster MP | 2015 | 中华高血压杂志2015，23，2： | 5 |
| 6 | Gastric cancer显示文摘 | Henk H Hartgrink Edwin PM Jansen Nicole CT van Grieken Cornelis JH van de Velde | 2009 | The Lancet . 2009 (9688)2009，，9688： | 4 |
| 7 | Gastric cancer显示文摘 | Henk H Hartgrink Edwin PM Jansen Nicole CT van Grieken Cornelis JH van de Velde | 2009 | The Lancet2009，，9688： | 2 |
| 8 | Biological correlates of FDG uptake in Non-small Cell Lung Cancer显示文摘 | De Geus-Oei LF Van Krieken JH Aliredjo RP | 2007 | Lung Cancer2007，55，1： | 1 |
| 9 | Enabling individu- alized therapy through nanotechnology 显示文摘 | Sakamoto JH Van de Ven AL Godin B | 2010 | Pharmacol Res2010，62，2： | 1 |
| 10 | Monocyte chemoattractant protein 1 ,interleukin 8, and chronic airways inflammation in COPD 显示文摘 | De Boer WI Sont JK Van Schadewijk A Stolk J van Krieken JH Hiemstra PS | 2000 | Journal of Pathol2000，190，5： | 1 |
| 11 | Heimlich valve treatment and outpatient management of bilateral metastatic pneumothorax显示文摘 | Van Hengel P Van de Bergh JH | 1994 | Chest1994，105，5： | 1 |
| 12 | Biological correlates of FDG uptake in non-small cell lung cancer显示文摘 | de Geus-Oei LF van Krieken JH Aliredjo RP | 2007 | Lung Cancer2007，55，： | 1 |
| 13 | Postpartum behaviour as predictor of weight change from before pregnancy to one year postpartum显示文摘 | Althuizen E van Poppel MN de Vries JH | 2011 | BMC Public Health2011，11，： | 1 |
| 14 | Cyclin D1 messenger RNA overexpression as a marker for mantle cell lymphoma显示文摘 | de Boer CJ van Krieken JH Kluin-Nelemans HC | 1995 | Oncogene1995，10，9： | 1 |
| 15 | Bronchioloalveolar adenocarcinoma and pulmonary langerhans cell histiocytosis in a patient with MUTYH-associated polyposis显示文摘 | vonder Thüsen JH van de Wetering MD Westermann AM | 2011 | J Clin Oncol2011，29，8： | 1 |
| 16 | The role of[18F]-2-fluoro-2-deoxy-d-glucose-positron emission tomography in thyroid nodules with indeterminate fine-needle aspiration biopsy:systematic review and meta-analysis of the literature显示文摘 | Vriens D de Wilt JH van der Wilt GJ | | 0，，20： | 1 |
| 17 | Distribution of endocrine cells in the gut of the impala(Aepyceros melampus)显示文摘 | Schoeman JH De Vos V Van Aswegen G | 1998 | Onderstepoort J Vet Res1998，65，1： | 1 |
| 18 | Injectable intraocular lens materials based upon hydrogels显示文摘 | De Groot JH van Beijma FJ Haitjema HJ | 2001 | Biomacromolecules2001，2，3： | 1 |
| 19 | Rapid method for determination of fat in faeces显示文摘 | Van de Kramer JH Bokkel H Weijers HA | 1949 | J Biol Chem1949，447，： | 1 |
| 20 | Presence and mechanism of knee articular cartilage degeneration after meniscal reconstruction in dogs显示文摘 | Van Tienen TG Heijkants RG de Groot JH | 2003 | Osteoarthritis Cartilage2003，11，1： | 1 |
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