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| 1 | 东北酸菜中产胞外多糖乳杆菌的分离筛选及其在酸乳中的应用显示文摘从东北酸菜中分离出97株乳杆菌菌株,并筛选出两株产酸快、产胞外多糖(EPS)的乳杆菌2号菌株和9号菌株。初步鉴定前者为干酪乳杆菌,后者为植物乳杆菌。在发酵剂(保加利亚乳杆菌和嗜热链球菌,LS)中混入等量的菌株2或9培养物(脱脂乳),所制备的酸乳中EPS质量浓度达34 mg/L,活菌总数可达2×108 mL-1以上。酸乳物性测定结果显示,产EPS菌株发酵的酸乳弹性好,相对粘度高,持水力强,乳清析出少。感官评定结果显示,与没有添加产EPS菌株发酵的酸乳相比,产EPS菌株LS+2与LS+9组合发酵酸乳风味分值较高,组织状态的分值差别较大,而酸度上没有显著差异。与物性测定结果一致。 | 张天琪 张雪 孔保华 Huttunen Eine 杨贞耐 | 2009 | 中国乳品工业2009，37，7： | 7 |
| 2 | Mesuaferrea stem bark extract induces apoptosis and inhibits metastasis in human colorectal carcinoma HCT 116 cells, through modulation of multiple cell signalling pathways显示文摘Considering the great potential of natural products as anticancer agents, the present study was designed to explore the molecular mechanisms responsible for anticancer activities of Mesua ferrea stem bark extract against human colorectal carcinoma. Based on MTT assay results, bioactive sub-fraction(SF-3) was selected for further studies using HCT 116 cells. Repeated column chromatography resulted in isolation of less active α-amyrin from SF-3, which was identified and characterized by GC-MS and HPLC methods. α-amyrin and betulinic acid contents of SF-3 were measured by HPLC methods. Fluorescent assays revealed characteristic apoptotic features, including cell shrinkage, nuclear condensation, and marked decrease in mitochondrial membrane potential in SF-3 treated cells. In addition, increased levels of caspases-9 and-3/7 levels were also observed in SF-3 treated cells. SF-3 showed promising antimetastatic properties in multiple in vitro assays. Multi-pathway analysis revealed significant down-regulation of WNT, HIF-1α, and EGFR with simultaneous up-regulation of p53, Myc/Max, and TGF-β signalling pathways in SF-3 treated cells. In addition, promising growth inhibitory effects were observed in SF-3 treated HCT 116 tumour spheroids, which give a hint about in vivo antitumor efficacy of SF-3 phytoconstituents. In conclusion, these results demonstrated that anticancer effects of SF-3 towards colon cancer are through modulation of multiple molecular pathways. | Muhammad Asif Armaghan Shafaei Aman Shah Abdul Majid Mohammed Oday Ezzat Saad S Dahham Mohamed B.Khadeer Ahamed Chern Ein Oon Amin Malik Shah Abdul Majid | 2017 | Chinese Journal of Natural Medicines2017，15，7： | 2 |
| 3 | Why Hold - Ups Occur: The selfenforcing range of contractual relationships 显示文摘 | KI EIN B | 1996 | Economic inquiry Oxtbrd University Press1996，34，3： | 1 |
| 4 | Adaptive wavdet thresholding for image denoising and eompression显示文摘 | Chang S G Ein Yu Vetlerli M | 2000 | IEEE Trans Image Processing2000，9，9： | 1 |
| 5 | Reliance on decision aids: an examination of auditors' assessment of management fraud 显示文摘 | Eining M M Jones D R Loebbecke J K | 1997 | Auditing: A Journal of Practice and Theory1997，16，2： | 1 |
| 6 | Single Incision Laparoscopic Total Gastrectomy and D2 Lymph Node Dissection for Gastric Cancer Using a Four-Access Single Port: The First Experience显示文摘 | Metin Ertem Emel Ozveri Hakan Gok Volkan Ozben T. ?olak S. H. Ein | 2013 | Case Reports in Surgery2013，，： | 1 |
| 7 | Pbotocatalysis of 4-nitrophenol using zinc phthalocyanine complexes 显示文摘 | MARAIS E KI EIN R ANTUNES E | 2007 | Journal of Molecular Catalysis A: Chemical2007，261，1： | 1 |
| 8 | Risk factor analysis of pla- sma cytokines in patients with coronary artery disease by a multiple- xed fluorescent immunoassay显示文摘 | Martins TB Anderson JL Muhlest ein JB | 2006 | Am J Clin Pathol2006，125，6： | 1 |
| 9 | Appendicitis in the child with a ventriculo-peritoneal shunt:a 30-year review显示文摘 | Ein SH Miller S Rutka JT | 2006 | Pediatr Surg2006，41，7： | 1 |
| 10 | Varieties with small dual varieties, I显示文摘 | Lawrence Ein | | 0，1986，： | 1 |
| 11 | Outcome signa- ture genes in breast cancer: is there a unique set? 显示文摘 | Ein - Dor L Kela I Getz G Givol D Domany E | 2005 | Bioinfor- matics2005，21，2： | 1 |
| 12 | Beispiel von,Berlin(west)显示文摘 | Kowarik L Zum menschlichen Einfluss auf FIora and vegetation-theoretische Konzepte and ein Quantifizierungsansatz am | 1988 | Landsch entwickl Umweltforsch1988，56，： | 1 |
| 13 | Correlation of Tei index obtained from tissue Doppler echocardiography with invasive measurements of left ventricular performance 显示文摘 | Su HM Ein TH Voon WC | 2007 | Eehocardiography2007，24，3： | 1 |
| 14 | Development of a simplified assay for the detection of neutralizing antibodies to Japanese encephalitis virus显示文摘 | Shirley H.L. Ting E’ein See Hwee Cheng Tan May Ann Lee Eng Eong Ooi | 2001 | Journal of Virological Methods2001，，1： | 1 |
| 15 | The surface fractal dimension of the soil-pore interface as measured by image analysis显示文摘 | Dathe A Eins S Niemeyer J | 2001 | Geoderma2001，103，： | 1 |
| 16 | The management of nonpigmented gallstones in children显示文摘 | Steven W Bruch Sigmund H Ein Catharine Rocchi | 2000 | Pediatr Surg2000，35，5： | 1 |
| 17 | Triglycer ide concentra- tion and ischemic heart disease:an eight year folowsup in the Co- penhagen male study显示文摘 | Jeppesin J H ein HO Suadicani P | 1998 | Circulation1998，97，10： | 1 |
| 18 | Arterial hypertension and stroke prevention: an update显示文摘 | Bornst ein N Silvestrelli G Caso V | 2006 | Clin Exp Hypertens2006，28，34： | 1 |
| 19 | The ramification divisors for branched coverings ofP k n显示文摘 | Lawrence Ein | 1982 | Mathematische Annalen1982，，4： | 1 |
| 20 | Auditors' Experience with Material Irregularities: Frequency, Nature, and Detectability显示文摘 | Loebbecke J K M Eining J J Willingham | 1989 | Auditing1989，，9： | 1 |
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