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    题名 作者 年代 出处 被引量
1Highly Pathogenic H5N1 Influenza Virus Infection in Migratory Birds显示文摘Jinhua Liu et al.College of Veterinary Medicine, China Agricultural University, Beijing 100094, China. 2005中国实验动物学报2005,13,S1:114
21994年中国糖尿病患病率及其危险因素显示文摘为调查全国糖尿病及糖耐量低减(IGT)的患病率及糖尿病危险因素,对全国19省市年龄≥25岁的224251人群进行横向普查,根据1985年WHO标准,年龄在25~64岁的213515人群中,糖尿病患病率为2.51%,糖耐量低减患病率为3.20%(按1990年全国人口年龄标化后患病率);新诊断糖尿病的比例(70.33%)明显高于已确诊的糖尿病者。现患病率是10年前的3.0倍左右,其中农村患病率的增长高于城市。经多因素logistic逐步回归分析显示,年龄、体重指数或腰臀围比、糖尿病家族史、高血压、低体力活动、高收入为非胰岛素依赖型糖尿病(NIDDM)的独立危险因素,而且在高收入人群中,低文化程度也为NIDDM的独立危险因素。Pan Xiaoren *, Yang Wenying, Liu Juan, et al. *Department of Endocrinology, China Japan Friendship Hospital, Beijing 100029 1997中华内科杂志1997,36,6:415
3Immunohisto chemical Study on the Effects of Pyrethroids on Gluta-mate and γ-Aminobutyric Acid in Rat Central Nervous System显示文摘Objective\ In order to study the effects of pyrethroids on glutamate (Glu) and gamma aminobutyric acid (GABA) in rat central nervous system. Methods\ Male SD rats were treated with permethrin (7 mg/kg, i.p) or cypermethrin (70 mg/kg, i.p) once a day for 3 days. Glu and GABA immunoreactive cells and transmitters in CNS were studied by immunohistochemical method. Results\ The total number, percentage of positive area and integral optical density of glutamate immunoreactive cell in cerebral cortex, hippocampus decreased significantly in permethrin or cypermethrin, while GABA was enhanced. Cypermethrin is more tent than permethrin on either Glu or GABA. Conclusion\ Disturbance of Glu and GABA is likely to play a role in the development of pyrethroids excitatory neurotoxicity.Wu Jianping, Lu Chun\+1, Wang Ying, et al. Wu Jianping, Lu Chun\+1, Wang Ying, et al. Institute of Toxicology, Nanjing Medical University, Nanjing\ 210029 Acta Universitatis Medicinalis Nanjing,19(6):450 1999The Journal of Biomedical Research1999,23,2:68
4全国第二次冠心病介入性治疗病例注册登记资料分析显示文摘目的 分析 1997年和 1998年我国冠心病介入性治疗发展趋势。方法 采用填写统一发放的表格的方法 ,收集 1997、1998两年各医院冠心病介入性治疗病例资料 ,进行回顾性分析。结果共注册经皮冠状动脉腔内成形术 (PTCA)病例总数 872 5例 ,来自全国范围内 75所医院 ,总成功数 83 69例 (95 9% )。其中 1997年 3 74 0例 ,成功 3 5 5 3例 (95 0 % ) ;1998年 4 985例 ,成功 4 816例 (96 6% )。共扩张病变 10 2 18处 ,成功 965 0处 ,病变成功率为 94 4 %。急性心肌梗死 (AMI)急诊PTCA 10 4 5例 ,成功10 0 1例 (95 8% )。全组患者发生重要并发症 95 9例 (11 0 % ) ,包括死亡 3 2例 (0 3 7% )。冠状动脉支架置入术 63 2 9例 ,共置入支架 774 8只 ,其中左冠状动脉主干置入支架 86只 (占 1 1% )。置入成功7677只 (99 1% )。发生重要并发症 5 10例 (8 1% ) ,包括死亡 2 5例 (0 4 0 % )。全部患者服用噻氯匹啶 ,其中 13 8例 (1 8% )发生粒细胞减少症。另外 ,注册登记冠状动脉斑块旋磨术 93例 (94支血管 ) ,成功率为 93 6%。结论 1997年和 1998年我国冠心病介入治疗例数有大幅度增长 ,两年内完成病例数远远超过过去 12年积累病例总数 ,成功率较过去有增加趋势 ,但地区间及医院间发展仍很不平衡。Section of Interventional Cardiology, Chinese Society of Cardiology, Chinese Medical Association, et al. (Correspondent: GAO Runlin. Fu Wai Hospital, PUMC & CAMS, Beijing 100037, China) 2000中华心血管病杂志2000,28,1:50
5Tectonic evolution of the Dabieshan orogen: In the view from polyphase deformation of the Beihuaiyang metamorphic zone显示文摘The Beihuaiyang metamorphic zone was formed by the Early Mesozoic collision of the North and South China Blocks. It consisted of the Foziling and Luzhenguan complexes and was thought to have never afforded a deep subduction. A similar feature of the deformation in the Dabieshan UHP metamorphic rocks implies that these different tectonic units share the same geodynamic background. The early stage of deformation can be preserved on account of their relatively shallower subduction than that for UHP rocks. On the basis of an analysis of the geo- logical structure and geochronological results, five deformational stages have been recognized: a D1-Early compressional deformation which represents the continental subduction; a D2-Early exhumation deformation producing a syn-convergence exhumation; a D3-Main deformation, represented by an exhumation deformation with Late Triassic age; a D4-Doming and its margin extensional gravity collapse deformation and finally a D5-regional extensional deformation of Cretaceous that was mostly introduced by the migmatization and plutonism.LIN Wei1, 2, Faure Michel3, WANG Qingchen1 & Arnaud Nicolas4 1. LTE, Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing 100029, China 2. Department of Earth and Planetary Sciences, Graduate School of Science, Nagoya University, Japan 3. ISTO, UMR CNRS 6113, Batiment Géosciences, Orléans Université d’Orléans, 45067 Orléans Cedex 2, France 4. UMR 6524 'Magmas et Volcans', 5 Rue Kessler, 63000 Clermont-Ferrand, France 2005Science China Earth Sciences2005,48,7:25
6Elimination of cholesterol in human endothelial cells显示文摘Eliminationofcholesterolinhumanendothelialcels.XiuRuijuan,DuanChonggao,LiHongwei,etal.InstituteofMicrocirculation,ChineseAcad...Xiu Ruijuan, Duan Chonggao, Li Hongwei, et al. Institute of Microcirculation, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100005, China. 1998Chinese Medical Journal1998,,1:26
7481例急性早幼粒细胞白血病完全缓解后随访报告显示文摘481例急性早幼粒细胞白血病经全反式维甲酸诱导达完全缓解后,分别接受4种不同的缓解后治疗方案,经随访2~87(中位数25)个月,从Kaplan-Meier生存曲线与生存概率比较,以化疗与维甲酸交替治疗组疗效较好。3年生存概率为0.768±0.062。持续单用维甲酸维持组疗效最差。Sun Guanlin Zhou Rongfu Wu Wen et al(The National Cooperarive Group of Leukemia Treatment with ATRA, 200025) 1994中华血液学杂志1994,15,8:24
8中日竞走运动员高原训练的生理机能及运动能力的研究显示文摘10名世居高原(2260米)的中国竞走运动员和10名居平原(10m)的日本竞走运动员在多巴(2366米),作4周高原训练。高原训练后期与前期、高原与平原相比,观察到有益的代偿性改变。如运动后的恢复心率(1分至1分10秒)下降加快(13次/分降至105次/分);在负荷心率相近条件下,步速加快(3.61m/s增至3.80m/s),无氧阈速度加快(中方,3.01增至3.22;日方,2.78增至3.30m/s);左室功能有改善(SV:日男由85.4→98.1ml;C1:中男由3.10→3.28L/m^2·min);乳酸—速度曲线右移(日男由7.2→5.4mM,中男由6.2→5.6mM);缓冲系统的能力有改善(女子:BE,—4.7→0.2mM;HCO_3,18.6→25.2mM);肺通气功能有所加强(MVV:中方,108.6→113.5L/min,日方,139.8→146.6L/min)。高原训练后,下平原比赛,中日各有8名队员提高了本人最好成绩。Li Hua, et al. (Qinghai Institute of Sports Science, Xining, China 810000)J. Aoki, et al(University of Zuntendo, Japan) Sino-Japanese Research Group for Altitude Training 1995体育科学1995,15,5:23
9Experimental Stody on Immediate Endosseous Implantation.显示文摘Screw type implants (ITI series) were implanted into the socket of extracted teeth of adult dogs to investigate the histologic recovery process of implantation. Two groupsTan Baosheng, et al. Beijing Hospital of Stomatology, Capital University of Medical Science, Beijing 100050. 1995Chinese Medical Journal1995,,9:23
10空气质量模型及参数选用导则显示文摘本研究是为了在大气污染物浓度估算中提供一个可以接受的技术分析的共同尺度,将所需用的空气质量模式分为三个等级。第一级模式作为在制定大气环境管理的法规和政策时主要应用的模式。第二、三级模式作为研究级模式。本文详细介绍了第一级模式的主要应用原则,简要介绍了第二、三级模式。Lin Hong(Chinese Research Academy of Environmental Sciences, Beijing 100012)Sang Jianguo(Beijing University,Beijing 100871)Xu Dahai et al.(The Research Academy of Meteorology, Beijing 100086) 1993环境科学研究1993,6,4:18
11Isolation and Identification of a Specific cDNA Mapping to the Bam HI-I2 and -LFragments within the Inverted Repeats ofUnique Long Re-gion (IRL) in the Genom e ofMarek′s Disease Herpesvirus (MDV) Oncogenic Strain Beijing-1显示文摘Objective\ To understand the transcription of BamHI L DNA fragment from genome of strong virulent GA strain of Marek′s disease herpesvirus (MDV) in lymphoblastoid tumor tissue induced by oncogenic strain Beijing 1 (a specific local strain in China) of MDV. Methods\ Two oligonucleotide primers were synthesized according to the reported sequence of \%meq\% gene an ideal oncogenic candidate and our previously determined sequence of BamHI L fragment of Marek′s disease herpesvirus (MDV), respectively. Reverse transcriptase PCR(RT PCR) assay was performed by using these primers and the mRNA as a template which was isolated from visceral lymphoblastoid tumors obtained from chickens artificially infected with strain Beijing 1 of oncogenic MDV. Southern blot molecular hybridization was further carried out to detect the product of RT PCR with digoxigenin labeled nucleotide probe from BamHI I2 and L fragment in the gene library of MDV strain GA, respectively. Results\ Two probes could simultaneously hybridize this cDNA amplified by RT PCR with a length of about 730 bp. Conclusion\ It is suggested that \%meq\% transcription could extend from the right hand end of BamHI I2 to the adjacent BamHI L, and the BamHI L region was likely to be transcribed in MDV induced lymphoblastoid tumors.Lu Chun, Wu Jianping, Zhang Xunhai, et al. Lu Chun, Wu Jianping, Zhang Xunhai, et al. Department of Microbiology and Immunology, Nanjing Medical University, Nanjing\ 210029 Acta Universitatis Medicinalis Nanjing, 19(6):447 1999The Journal of Biomedical Research1999,23,2:13
12南方阔叶树材干燥初期应变特点的研究显示文摘在不同温度和平衡含水率条件下研究南方阔叶树材干燥初期应变特点。试验结果表明,干燥初期表层呈现伸张弹性应变和塑性应变,内层为压缩应变,伸张弹性应变的最大值是产生表裂的主要原因,塑性应变而引起的表层固定变形是产生内裂的原因。弹性和塑性应变受平衡含水率的影响较大,并且与含水率梯度存在相关关系、干燥初期阶段的延续时间,可由表层达到最大伸张应变时的含水率与初含水率的比值来确定。Guo Yanming et al. (Research Institute of Wood Industry,CAF,Beijing 100091) 1995木材工业1995,9,4:13
13Nerve Growth Factor Prevents the Apoptosis-associated Increase in Acetylcholinesterase Activity after Hydrogen Peroxide Treatment by Activating Akt显示文摘Acetylcholinesterase (疼痛) 被认为玩结果显示出的重要角色 duringapoptosis.Our 那 H_2O_2 导致了疼痛活动,功能的标记 inapoptosis,象 neuronal 一样 PC 12 房间的增加。谷胱甘肽,涉及细胞的氧化还原作用动态平衡,禁止了疼痛活动的增加,建议在这个过程的那个反应的氧种类(ROS ) 千盐湖钥匙角色。进一步的调查证明疼痛的举起在 Akt,从进 cytosol 的线粒体的细胞色素 c 的版本,和 caspase 家庭成员的激活的降级以后被观察。神经生长因素(NGF ) 什么时候是在场的,与 Akt 水平,疼痛的举起,细胞色素 c 散开,以及 apoptosis 的维护,显著地在对待 H_2O_2 的 PC12 细胞被稀释。然而, wortmannin, PI3K/Aktpathway 的一个禁止者,加速了 apoptosis 并且增加了疼痛活动。过去表示 ofconstitutively 激活 Akt,它是 NGF receptorTrkA,推迟的 mitochondrial 倒塌和疼痛活动的禁止的举起的一个下游的发信号元素。因此, NGF preventedapoptosis 和由激活 Akt 小径并且稳定线粒体的功能的疼痛活动的举起。Hua JIANG~(1,3) Jingya ZHANG~(1,3) Hui ZHU~(1,3) Hong LI~2 and Xuejun ZHANG~1 ~1Laboratory of Molecular Cell Biology,Institute of Biochemistry and Cell Biology,Shangha Institutes for Biological Sciences,Chinese Academy of Sciences,Shanghai 200031,China ~2DEFEMA,Faculté de Medecine et de Pharmacie,University of Rouen,Rouen 76821,France ~3Graduate school of the Chinese Academy of Sciences,Beijing 100080,China 2007Acta Biochimica et Biophysica Sinica2007,39,1:9
14Fura-2/AM法测定突触体内游离Ca^(2+)浓度的方法显示文摘采用新型Ca2+荧光指示剂Fura-2,测定冷冻伤性脑水肿时突触体内游离钙的离子浓度。Chen Liuhua Yan Yujia He Zhengwen, et al(Neurological and Neurosurgical Institute of Ncurosurgery, Xiangya Hospital, Hunan Medical University, Changsha 410008) 1998湖南医科大学学报1998,23,4:9
15Study on expresion of adherent proteins related to regulation of hematopoiesis in long-term cultured human bone marrow stromal cells显示文摘Studyonexpresionofadherentproteinsrelatedtoregulationofhematopoiesisinlongtermculturedhumanbonemarrowstromalcels.LiuJiewen,...Liu Jiewen, Qi Shuling, E de Wynter, et al. Institute of Hematology, CAMS and PUMC, Tianjin 300020, China. 1998Chinese Medical Journal1998,,2:8
16生物反馈治疗高血压临床疗效剖析显示文摘对89例Ⅰ/Ⅱ期高血压病人经一年的生物反馈治疗,发现疗效受多种生物心理社会因素的影响,其中收缩压稍低、高神经质(情绪不稳定)、愤怒分值和焦虑分值较高,以及社会支持程度较高的病人其治疗效果较好。Zhang Sufang et al, Depart-ment of Medical Psychology, Beijing Medical University. Beijing 100083 1995中国心理卫生杂志1995,9,4:8
17Comparative Study on the Long-term Effect of Permanent Embolization of Hepatic Artery with Bletilla Striata in Patients with 显示文摘ComparativeStudyontheLong-termEffectofPermanentEmbolizationofHepaticArterywithBletillaStriatainPatientswithPrimaryLiverCancer...FENG Gansheng Cramann B ZHENG Zhuansheng et al(Department of Radiology,Xiehe Hospital, Tongji Medical University,Wuhan 430030 Abteilung fur Radio-Diagnostik,Universitatsklinik,Homburg/Saar,Deutschland) 1996Journal of Huazhong University of Science and Technology(Medical Sciences)1996,16,2:8
18Hemodynamic Effects of Inhaled Nitric Oxide in Patients with Pulmonary Hypertension.显示文摘Twelve patients with pulmonary hypertension (primary pulmonary hypertension in 3 cases, secondary to recurrent pulmonary embolism in 4 cases, chronic obstructive pulmonary disease in 2 cases and complicated with congeni-Zhao Yiju et al. Cardiovascular Institute and Fu Wai Hospital. CAMS Beij- ing 100037. National Medical Journal of China. 1995Chinese Medical Journal1995,,9:7
19中风病始发态证候影响因素的研究显示文摘调查分析性别、年龄、职业、伴发疾病、既往史对1663例中风病始发态患者证候得分均值和发生概率的影响。结果显示:男性疾湿证显著高于女性;年龄对证候有显著影响,并与气虚证、痰湿证、血瘀证呈显著正相关关系;职业对证候无规律性影响;伴发疾病评分与风证、火热证、痰湿证、气虚证、阴虚阳亢证里显著正相关关系。提示临床辨证、证候研究、新药研制中要重视和考虑上述因素的影响。Wang Shundao Ren Zhanli Du Menghua et, al.(Xingtai Municipal people’s Hospital, Hebei 054031)(Beijing University of TCM, Beijing 100029) 1996北京中医药大学学报1996,19,4:6
20Schur convexity for a class of symmetric functions显示文摘The Schur convexity and concavity of a class of symmetric functions are discussed, and an open problem proposed by Guan in 'Some properties of a class of symmetric functions' is answered. As consequences, some inequalities are established by use of the theory of majorization.CHU YuMing 1, XIA WeiFeng 1 & ZHAO TieHong 2 1 Department of Mathematics, Huzhou Teachers College, Huzhou 313000, China 2 Institut de Mathmatiques, Universit Pierre et Marie Curie, Paris F-75252, France 2010Science China Mathematics2010,53,2:6
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