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| 1 | Mycoplasma infections and different human carcinomas显示文摘AIM To explore relationships between human carcinomas and mycoplasma infection.METHODS Monoclonal antibody PD4, which specifically recognizes a distinct protein from mycoplasma hyorhinis, was used to detect mycoplasma infection in different paraffinembedded carcinoma tissues with immunohistochemistry. PCR was applied to amplify the mycoplasma DNA from the positive samples for confirming immunohistochemistry.RESULTS Fifty of 90 cases (56%) of gastric carcinoma were positive for mycoplasma hyorhinis. In other gastric diseases, the mycoplasma infection ratio was 28% (18/49) in chronic superficial gastritis, 30% (14/ 46) in gastric ulcer and 37% (18/ 49) in intestinal metaplasia. The difference is significant with gastric cancer (X2=12.06, P<0.05). In colon carcinoma, the mycoplasma infection ratio was 55.1% (32/58), but it was 20.9% (10/49) in adenomarous polyp (X2=13.46, P<0.005).Gastric and colon cancers with high differentiation had a higher mycoplasma infection ratio than those with low differentiation (P< 0.05). Mycoplasma infection in esophageal cancer, lung cancer, breast cancer and glioma was 50.9% (27/53), 52.6% (31/ 59), 39.7%(25/63) and 41% (38/91), respectively. The mycoplasma DNA was successfully amplified with the DNA extracted from the cancer tissues that were positive for mycoplasma infection (detected with antibody PD4).CONCLUSION There was high correlation between mycoplasma infection and different cancers, which suggests the possibility of an association between the two. The mechanism involved in oncogenesis by mycoplasma remains unknown. | Su Huang Ji You Li Jan Wu Lin Meng Cheng Chao Shou Beijing Institute for Cancer Research, Peking University School of Oncology, Beijing 100034. ChinaSu Huang, received B. A from Jiangxi Medical College of China in 1994. Now she is a graduate student pursuing a Ph. D degree at the Peking University School of Oncology. | 2001 | World Journal of Gastroenterology2001，7，2： | 18 |
| 2 | Retroperitoneal laparoscopic radical nephrectomy: the Cleveland clinic experience 显示文摘 | Gill IS Schweizer D Hobart MG | 2000 | J Urol2000，163，： | 2 |
| 3 | Toxic injury to epatic sinusoids: sinusoidal obstruction syndrome ( veno-occlusive disease) 显示文摘 | DELEVE L D SHULMAN H M MCDONALD G iS | 2002 | Semin Liver Dis2002，22，： | 1 |
| 4 | Single port transumbilical (E-NOTES) donor nephrectomy 显示文摘 | Gill IS Canes D Aron M | 2008 | J Urol2008，180，41： | 1 |
| 5 | Outpatient adrenalectomy显示文摘 | Gill IS Hobart MG Schweizer D | 2004 | J Urol2004，163，3： | 1 |
| 6 | Quality improvement guidelines for en-dovasculartreatment of iliacartery occlusive disease 显示文摘 | T set is D Uberoi R | 2008 | Cardiovasc Intervent Radi-ol2008，31，2： | 1 |
| 7 | Robotic intracorporeal ortho- topic ileal neobladder: replicating open surgical principles 显示文摘 | Goh AC Gill IS Lee D J | 2012 | Eur Urol2012，62，5： | 1 |
| 8 | Regularity Preserving Image Interpolation显示文摘 | CAREY W K CHUAND D B HEMAN IS S | | 0，，09： | 1 |
| 9 | Improved antimicrobial peptides based on acyl-lysine oligomers显示文摘 | Radzishevsky IS Rotem S Bourdetsky D | 2007 | Nature Biotechnology2007，25，6： | 1 |
| 10 | The application of the combined eorticotmpin-releasing hormone plus desmopressin stimulation during petrosal sinus sampling is both sensitive and specific in differentiating patients with Cushing's disease from patients with the occult ectopie adrenoeortieotmpin syndrome显示文摘 | Tsagarakis S Vassiliadi D Kaskarelis IS | 2007 | J Clin Endocfinol Metab2007，92，： | 1 |
| 11 | Potential for reduced toxicity and dose escalation in the treatment of inoperable non-small-cell lung cancer:a comparison of intensity modulated radiation therapy(IMRT),3D conformal radiation,and elective nodal irradiation显示文摘 | Grills IS Yan D Martinez AA | 2003 | Int J Radiat Oncol Biol Phys2003，57，3： | 1 |
| 12 | Pheochromocy- toma inherited associations, bilaterality, and cortex preserva- tion显示文摘 | Inabnet W B Carag liano P Pertsem lid is D | 2000 | Surgery2000，128，6： | 1 |
| 13 | External quality assessment scheme and laboratory accreditation in Indonesia显示文摘 | Timan IS Aulia D Santosow | 2002 | Rinsho Byori2002，50，2： | 1 |
| 14 | AMP-Activated Protein Kinase Beta Subunit Tethers Alpha and Gamma Subunits via Its C-Terminal Sequence(186-270)显示文摘 | Iseli T J Walter M van D B J | 2005 | J Biol Chem2005，280，13： | 1 |
| 15 | Antibiotic susceptibility pattern of urinary isolates in Imphal (Manipur),India显示文摘 | Yengkokpam C Ingudam D Yengkokpam IS | | 0，，03： | 1 |
| 16 | Foot strike patterns and collision forces in habitually barefoot versus shod runners显示文摘 | Lieberman DE Venkadesan M Werbel WA Daoud AI D'Aeandrea S Davis IS | | 0，，： | 1 |
| 17 | The renal sequelae of anovel triphasicapp roach to blood loss reduction during hepatic resection 显示文摘 | Moug SJ Smith D Wilson IS | 2006 | Eur J Surg Oncol2006，32，4： | 1 |
| 18 | Retroperitoneal laparoscopic radical nephrectomy:the cleveland clinic experience显示文摘 | Gill IS Schweizer D Hobart MG | 2000 | J Urol2000，163，： | 1 |
| 19 | E2F activity is essential for survival of Myc-overexpressing human cancer cells显示文摘 | Santoni-Rugiu E Duro D Farkas T Mathiasen IS Jaattela M Bartek J | 2002 | Oncogene2002，21，42： | 1 |
| 20 | Intrathecal drug the rapy for chronic pain: from basic science to clinicai practice 显示文摘 | Patrick M D Peter SS Denn is M F | 1999 | Anesthesiology1999，91，6： | 1 |
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