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1Confocal laser endomicroscopy and immunoendoscopy for real-time assessment of vascularization in gastrointestinal malignancies显示文摘Gastrointestinal cancers represent a major cause of morbidity and mortality,with incomplete response to chemotherapy in the advanced stages and poor prognosis.Angiogenesis plays a crucial part in tumor growth and metastasis,with most gastrointestinal cancers depending strictly on the development of a new and devoted capillary network.Confocal laser endomicroscopy is a new technology which allows in vivo microscopic analysis of the gastrointestinal mucosa and its microvascularization during ongoing endoscopy by using topically or systemically administered contrast agents.Targeting markers of angiogenesis in association with confocal laser endomicroscopic examination(immunoendoscopy),as a future challenge,will add functional analysis to the morphological aspect of the neoplastic process.This review describes previous experience in endomicroscopic examination of the upper and lower digestive tract with emphasis on vascularization,resulting in a broad spectrum of potential clinical applications,and also preclinical research that could be translated to human studies.Dan Ionut Gheonea Tatiana Crtnǎ Tudorel Ciurea Carmen Popescu Anca Bǎdǎrǎu Adrian Sǎftoiu 2011World Journal of Gastroenterology2011,17,1:6
2健康领域的文化能力显示文摘1背景 尽管人类对其他社会的兴趣纵贯历史的各个阶段,但是检验不同文化概念对人类健康实践的影响从20世纪才开始,当时是伴随着长期的人类学田野调查产生的,这些田野调查揭露了不同文化之间相关卫生实践的多样性、复杂性和连续性。Napier A D Ancarno C Butler B Calabrese j Chater A Chatterjee H Guesnet F Home R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams AC Willott C Wilson J Woolf K 2016中国卫生政策研究2016,9,2:5
3欧洲和中国的心脏与肾脏远程缺血预适应研究:一项随机对照试验显示文摘远程缺血预适应(remote ischemic preconditioning,RIPC)对经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术后造影剂肾病(contrast-induced nephropathy,CIN)的潜在保护作用尚待确定。该研究为双盲、随机、安慰剂对照的多中心研究,纳入年龄〈85岁,肾清除率为30~60mL/(min·1.73m^2)的有临床适应证的患者,除了直接PCI外均按1∶1给予RIPC或标准治疗。主要终点是CIN的发生率。次要终点是围手术期心肌梗死(peri-procedural myocardial infarction,PMI)的发生率。刘青 叶鹏 Moretti C Cerrato E Cavallero E Lin S Rossi ML Picchi A Sanguineti F Ugo F Palazzuoli A Bertaina M Presbitero P Shao-Liang C Pozzi R Giammaria M Limbruno U Lefèvre T Gasparetto V Garbo R OmedèP Sheiban I Escaned J Biondi-Zoccai G Gaita F Perl L D'Ascenzo F 2018中华高血压杂志2018,26,4:3
4Surveillance of contagious bovine pleuropneumonia in Switzerland 显示文摘Stark K D C Vicari A Kihm U 1995Rev Sci Tech1995,14,:2
5文化、不平等性与卫生服务提供显示文摘1动态不平等性对基层医疗卫生人力的影响 政治、社会、文化、专业群体皆建立在一致且常规的人类行为之上。当遭受巨大变革和内外压力时,这些群体会变得十分脆弱。尤其在动荡时期,这些群体往往更关注社会和文化的差异性,而非二者的一致性。尽管社会中的个体思维和行为会呈现较大的差异,但对健康的感知具有统一性,并在更广范围人群内尤为突出,这主要归因于文化价值观的作用。广义的文化心态会随着时间和地理位置的不同而不同,就像健康的社会决定因素也会因文化类型的不同而产生差异。Napier A D Ancarno C Butler B Calabrese J Chater A Chatterjee H Guesnet F Horne R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams A C Willott C Wilson J Woolf K 2016中国卫生政策研究2016,9,3:2
6Kontrastmittelsonografie bei B-Bild-morphologisch unklaren Leberraumforderungen – Diagnostische Treffsicherheit im klinischen Alltag (DEGUM-Multicenter – Studie)显示文摘D Strobel K Seitz W Blank A Schuler C Dietrich A Herbay M Friedrich-Rust G Kunze D Becker U Will W Kratzer F Albert C Pachmann K Dirks H Strunk C Greis T Bernatik 2008Ultraschall in Med2008,,05:2
7Competition between fusion-evaporation and multifragmentation in central collisions in ^(58)Ni+^(48)Ca at 25A MeV显示文摘The experimental data concerning the58Ni+48Ca reaction at Elab(Ni)=25A MeV,collected by using the CHIMERA 4π device,have been analyzed in order to investigate the competition among different reaction mechanisms for central collisions in the Fermi energy domain.As a main criterion for centrality selection we have chosen the flow angle(flow) method,making an event-by-event analysis that considers the shape of events,as it is determined by the eigenvectors of the experimental kinetic-energy tensor.For the selected central events(flow >60°) some global variables,good to characterize the pattern of central collisions have been constructed.The main features of the reaction products were explored by using different constraints on some of the relevant observables,like mass and velocity distributions and their correlations.Much emphasis was devoted,for central collisions,to the competition between fusion-evaporation processes with subsequent identification of a heavy residue and a possible multifragmentation mechanism of a well defined(if any) transient nuclear system.Dynamical evolution of the system and pre-equilibrium emission were taken into account by simulating the reactions in the framework of transport theories.Different approaches have been envisaged(dynamical stochastic BNV calculations + sequential SIMON code,QMD,CoMD,etc.).Preliminary comparison of the experimental data with BNV calculations shows reasonable agreement with the assumption of sequential multifragmentation emission in the mass region of IMFs close to the heavy residues.Possible deviations from sequential processes were found for those IMFs in the region of masses intermediate between the mass of heavy residues and the mass of light IMFs.Further simulations are in progress.The experimental analysis will be enriched also by information obtained inspecting the IMF-IMF correlation function,in order to elucidated the nature of space-time decay property of the emitting source associated with events having the largest IMF multiplicity.FRANCALANZA L ABBONDANNO U AMORINI F BARLINI S BINI M BOUGAULT R BRUNO M CARDELLA G CASINI G AGOSTINO M D' De FILIPPO V De SANCTIS J GERACI E GIUSSANI A GRAMEGNA F GUIOT B KRAVCHUK V La GUIDARA E LANZALONE G Le NEINDRE N MAIOLINO C MARINI P MORELLI L OLMI A PAGANO A PAPA M PIANTELLI S PIRRONE S POLITI G POGGI G PORTO F RUSSOTTO P RIZZO F VANNINI G VANNUCCI L 2013Nuclear Science and Techniques2013,24,5:2
8可变排量控制技术:利用关缸控制排量的未来车用汽油机显示文摘利用可变排量控制技术(DoD)可明显改善汽油机的部分负荷效率。DoD在部分负荷时关掉部分气缸。剩下的工作气缸运行负荷升高,换气损失因而降低。全负荷时仍用所有气缸工作。GM公司介绍的技术可在复杂性增加最少的情况下集成于下置凸轮轴式发动机。在汽车方面采取的措施,如发动机主动支承和车内主动降噪系统则有利于更彻底地使用DoD,从而进一步降低燃油耗。AIbertson W C 2008国外内燃机2008,40,2:2
9A continuum method for modeling surface tension显示文摘Brackbill J U Kothe D B Zemach C 1992Journal of Computational Physics1992,100,2:1
10Photolytic debromination of decabromodiphenyl ether (BDE 209) 显示文摘SODERSTROM G SELLSTROM U WIT C A D 2004Environ Sci Technol2004,38,:1
11Barley glutamyl tRNAGIu reductase:mutations affecting haem inhibition and enzyme activity显示文摘VOTHKNECHT U C KANNANGARA C G VON WETTSTEIN D 1998Phytochemistry1998,47,:1
12The AutoPap system for p rimary screening in cervical cytology 显示文摘Wilbur D C Prey M U Miller W M 2008Acta Cytol2008,42,5:1
13On the GI/M/1/N queue with working vacations-analytic analysis and computation显示文摘Banik A D Gupta U C Pathak S S 2007Applied Mathematics Modeling2007,,:1
14A continuum method for modeling surface tension显示文摘Brackbill J U Kothe D B Zemach C 1992J Computational Physics1992,100,2:1
15The role of peers and families in predicting the lineliness level of adolescents显示文摘 Ayhan D 2003The Journal of Psychology2003,137,2:1
16A continuum method for modeling surface tension 显示文摘Brackbill J U Kothe D B Zemach C 1992Journal of Computational Physics1992,100,:1
17Innovative ceramic materials for porous medium burners I显示文摘Pickenacker O Pickenacker K Wawrzinek K Trimis D Pritzkow W E C Miiller C Goedtke P Papenburg U Adler J Standke G Heymer H Tauscher W Jansen F 1999Interceram:International Ceramic Review1999,48,5:1
18The TGF-β-smad net-work:introducing bioinformatic tools显示文摘Kloos D U Choi C Wingender E 2002Trends in Gene-ties2002,18,:1
19Surveillance of contagious bovine pleuropneumonia in Switzerland 显示文摘Staerk K D C Vicari A Kihm U 1995Rev Sci Tech1995,14,:1
20Targeting axons to specific fiber tracts in vivo by altering cadherin expression显示文摘Treubert-Zimmermann U Heyers D Redies C 2002J Neurosci2002,22,:1
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