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| 1 | Bile leakage after loop closure vs clip closure of the cystic duct during laparoscopic cholecystectomy:A retrospective analysis of a prospective cohort显示文摘BACKGROUND Laparoscopic cholecystectomy(LC)is one of the most frequently performed surgical procedures.Cystic stump leakage is an underestimated,potentially life threatening complication that occurs in 1%-6%of the patients.With a secure cystic duct occlusion technique during LC,bile leakage becomes a preventable complication.AIM To investigate the effect of polydioxanone(PDS)loop closure of the cystic duct on bile leakage rate in LC patients.METHODS In this retrospective analysis of a prospective cohort,the effect of PDS loop closure of the cystic duct on bile leakage complication was compared to patients with conventional clip closure.Logistic regression analysis was used to develop a risk score to identify bile leakage risk.Leakage rate was assessed for categories of patients with increasing levels of bile leakage risk.RESULTS Of the 4359 patients who underwent LC,136(3%)underwent cystic duct closure by a PDS loop.Preoperatively,loop closure patients had significantly more complicated biliary disease compared to the clipped closure patients.In the loop closure cohort,zero(0%)bile leakage occurred compared to 59 of 4223(1.4%)clip closure patients.For patients at increased bile leakage risk(risk score≥1)rates were 1.6%and up to 13%(4/30)for clip closure patients with a risk score≥4.This risk increase paralleled a stepwise increase of actual bile leakage complication for clip closure patients,which was not observed for loop closure patients.CONCLUSION Cystic duct closure with a PDS loop during LC may reduce bile leakage in patients at increased risk for bile leakage. | Sandra C Donkervoort Lea M Dijksman Aafke H van Dijk Emile A Clous Marja A Boermeester Bert van Ramshorst Djamila Boerma | 2020 | World Journal of Gastrointestinal Surgery2020，12，1： | 4 |
| 2 | Systematic review of cystic duct closure techniques in relation to prevention of bile duct leakage after laparoscopic cholecystectomy显示文摘AIM To study the effect of different techniques of cystic duct closure on bile leakage after laparoscopic cholecystectomy(LC) for biliary disease.METHODS A systematic search of MEDLINE, Cochrane and EMBASE was performed. Rate of cystic duct leakage(CDL) was the primary outcome. Risk of bias was evaluated. Odds ratios were analyzed for comparison of techniques and pooled event rates for non-comparative analyses. Pooled event rates were compared for each of included techniques.RESULTS Out of 1491 articles, 38 studies were included. A total of 47491 patients were included, of which 38683(81.5%)underwent cystic duct closure with non-locking(metal)clips. All studies were of low-moderate methodological quality. Only two studies reported separate data on uncomplicated and complicated gallbladder disease. For overall CDL, an odds ratio of 0.4(95%CI: 0.06-2.48)was found for harmonic energy vs clip closure and an odds ratio of 0.17(95%CI: 0.03-0.93) for locking vs non-locking clips. Pooled CDL rate was around 1% for harmonic energy and metal clips, and 0% for locking clips and ligatures. CONCLUSION Based on available evidence it is not possible to either recommend or discourage any of the techniques for cystic duct closure during LC with respects to CDL,although data point out a slight preference for locking clips and ligatures vs other techniques. No separate recommendation can be made for complicated gallbladder disease. | Aafke H van Dijk Stijn van Roessel Philip R de Reuver Djamila Boerma Marja A Boermeester Sandra C Donkervoort | 2018 | World Journal of Gastrointestinal Surgery2018，10，6： | 3 |
| 3 | Thermal stability of retained austenite in TRIP steels studied by synchrotron X-ray diffraction during cooling显示文摘 | Van Dijk N H Butt A M | 2005 | Acta Materialia2005，53，： | 1 |
| 4 | Transcriptional repression by Oshox1,a novel homeodomain leucine zipper protein from rice显示文摘 | Meijer A H Scarpella E Van Dijk E L | 1997 | Plant J1997，11，： | 1 |
| 5 | Avian de- fensins 显示文摘 | van Dijk A Veldhuizen E J Haagsman H P | 2008 | Veterinary Immunology and Immunopathology2008，124，1： | 1 |
| 6 | 显示文摘 | de With G van Dijk H J A | 1984 | Mater Res Bull1984，19，： | 1 |
| 7 | Validation of a water-gas shift reactor model based on a commercial Fe Cr catalyst for pre-combustion CO2 capture in an IGCC power plant显示文摘 | Van Dijk H A J Cohen D Hakeem A A | 2014 | International Journal of Greenhouse Control2014，29，： | 1 |
| 8 | Two functionauy and chmically distinct immunomodulatory compounds in the gel of Aloe vera显示文摘 | Van Enckevort P H Van Dijk H | 1988 | J Ethnopharmacol1988，23，： | 1 |
| 9 | Avian defensins显示文摘 | van Dijk A Veldhuizen E J A Haagsman H P | | 0，，1： | 1 |
| 10 | Translucent Y3Al5O12 ceramics显示文摘 | de With G van Dijk H J A | 1984 | Mater Res Bull1984，19，12： | 1 |
| 11 | Optical performance of multifocal intraocular lenses 显示文摘 | Holladay JT Van Dijk H Lang A | 1990 | J Cataract Refract Surg1990，16，6： | 1 |
| 12 | In vitro cyanide release of four Prussian bluc salts used for the troatment of cesium contaminated persons显示文摘 | Verzijl J M Joore H C A van Dijk A | 1993 | Clinical Toxicology1993，31，4： | 1 |
| 13 | RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling显示文摘 | MATTIROLI F VISSERS J H A VAN DIJK W J | 2012 | Cell2012，150，6： | 1 |
| 14 | Avian defensins 显示文摘 | VAN DIJK A VELDHUIZEN E J HAAGSMAN H P | 2008 | Veterinary Immunology and Immu- nopathology2008，124，12： | 1 |
| 15 | Pneumococcal immune adherence to human erythrocytes显示文摘 | J M Hament H van Dijk A Fleer | 2003 | European Journal of Clinical Investigation2003，33，： | 1 |
| 16 | Prolongation of vase life of cut rose via introduction of genes coding for antibacterial activity: somatic embryogenesis and agrobacterium-mediated transformation显示文摘 | Derks F H M Van Dijk A J Hnaisch-Ten Catc C H | 1995 | Acta Hort1995，405，： | 1 |
| 17 | Asymmetric block copolymers confined in a thin film显示文摘 | Huinink H P Brokken-Zijp J C M van Dijk M A | 2000 | Journal of Chemical Physics2000，112，5： | 1 |
| 18 | Translucent Y3Al5O12 ceramics显示文摘 | de WITH G van DIJK H J A | 1984 | Mater Res Bull1984，19，： | 1 |
| 19 | Surface-induced transitions in thin films of asymmetric diblock copolymers显示文摘 | Huinink H P van Dijk M A BrokkewZijp J C M | 2001 | Macromolecules2001，34，15： | 1 |
| 20 | Steady-state isotopic transient kinetic analysis of the Fischer-Tropsch synthesis reaction over cobalt-based catalysts显示文摘 | Van Dijk H A J Hoebink J H B J Schouten J C | 2001 | Chemical Engineering Science2001，56，4： | 1 |
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