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| 1 | 胰岛素瘤的诊治经验与思考显示文摘胰岛素瘤是最常见的功能性胰腺神经内分泌肿瘤,极易被误诊误治。近年来,随着诊治体系的建立与不断完善,胰岛素瘤的误诊率明显下降,但由于不同医疗机构的诊治水平参差不齐,其诊断与治疗仍存在误区。本文结合北京协和医院的诊治经验,从定性诊断和定位诊断、手术治疗和非手术综合治疗及围手术期管理等方面总结胰岛素瘤的诊治进展,借助多学科团队的快速发展,不断突破诊治困惑和瓶颈,从而进一步提高我国胰岛素瘤的规范化诊治水平。 | 张太平 邱江东 冯梦宇 赵玉沛 | 2018 | 中华外科杂志2018，56，11： | 14 |
| 2 | 胰腺中段切除术治疗良性和低度恶性胰腺颈体部肿瘤:附32例报告显示文摘目的:探讨胰腺中段切除术(MP)治疗良性和低度恶性胰腺颈体部肿瘤的疗效。方法:回顾性分析2005年8月—2013年2月收治的32例胰腺颈体部良性和低度恶性肿瘤行MP患者资料(MP组),并与同期因良性和低度恶性胰腺肿瘤行胰十二指肠切除术(PD)的30例(PD组)和行胰体尾切除术(DP)的36例(DP组)患者资料进行比较。结果:MP组、PD组、DP组平均手术时间分别为(180.8±56.4)、(279.6±79.2)、(190.4±62.3)min;平均术中出血量分别为(196.5±185.7)、(482.6±288.5)、(320.7±240.3)mL;胃肠道功能恢复时间分别为(3.6±1.6)、(5.2±2.3)、(4.1±1.9)d;新增糖尿病例数分别为1、5、9例;术后需要补充胰酶例数分别为0、8、5例,以上指标3组间差异均有统计学意义(均P<0.05)。MP组、PD组、DP组术后胰瘘发生率(18.8%、12.5%、25.0%)以及其他围手术期指标差异均无统计学意义(均P>0.05)。平均随访38个月,各组均无肿瘤复发。结论:MP治疗良性或低度恶性胰腺颈体部肿瘤是一项合理的技术,能更好地保护胰腺外分泌和内分泌功能。 | 李伟强 窦科峰 段涛 党立力 黄启科 | 2014 | 中国普通外科杂志2014，23，3： | 6 |
| 3 | Modified Blumgart anastomosis without pancreatic duct-to-jejunum mucosa anastomosis for pancreatoduodenectomy:a feasible and safe novel technique显示文摘Objective:This study proposed a modified Blumgart anastomosis(m-BA)that uses a firm ligation of the main pancreatic duct with a supporting tube to replace the pancreatic duct-to-jejunum mucosa anastomosis,with the aim of simplifying the complicated steps of the conventional BA(c-BA).Thus,we observe if a difference in the risk of postoperative pancreatic fistula(POPF)exists between the two methods.Methods:The m-BA anastomosis method has been used since 2010.From October 2011 to October 2015,147 patients who underwent pancreatoduodenectomy(PD)using BA in Tianjin Medical University Cancer Institute and Hospital were enrolled in this study.According to the type of pancreatojejunostomy(PJ),50 patients underwent m-BA and 97 received c-BA.The two patient cohorts were compared prospectively to some extent but not randomized,and the evaluated variables were operation time,the incidence rate of POPF,and other perioperative complications.Results:The operation time showed no significant difference(P>0.05)between the two groups,but the time of duct-to-mucosa anastomosis in the m-BA group was much shorter than that in the c-BA group(P<0.001).The incidence rate of clinically relevant POPF was 12.0%(6/50)in the modified group and 10.3%(10/97)in the conventional group(P>0.05),which means that the modified anastomosis method did not cause additional pancreatic leakage.The mean length of postoperative hospital stay of the m-BA group was 23 days,and that of the c-BA group was 22 days(P>0.05).Conclusions:Compared with the conventional BA,we suggest that the modified BA is a feasible,safe,and effective operation method for P J of PD with no sacrifice of surgical quality.In the multivariate analysis,we also found that body mass | Xiaoqing Wang Yang Bai Mangmang Cui Qingxiang Zhang Wei Zhang Feng Fang Tianqiang Song | 2018 | Cancer Biology & Medicine2018，15，1： | 6 |
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