| 1 | New parameter in diagnosis of acute appendicitis:Platelet distribution width显示文摘AIM:To investigate the diagnostic accuracy of the mean platelet volume and platelet distribution width in acute appendicitis.METHODS:This retrospective,case-controlled study compared 295 patients with acute appendicitis(Group?Ⅰ),100 patients with other intra-abdominal infections(GroupⅡ),and 100 healthy individuals(GroupⅢ)between January 2012 and January 2013.The age,gender,and white blood cell count,neutrophil percentage,mean platelet volume,and platelet distribution width values from blood samples were compared among the groups.Statistical analyses were performed using SPSS for Windows 21.0 software.In addition,the sensitivity,specificity,positive and negative predictive values and likelihood ratios,and diagnostic accuracy were calculated.RESULTS:The mean ages of patients were 29.9±12.0years for Group?Ⅰ,31.5±14.0 years for GroupⅡ,and30.4±13.0 years for GroupⅢ.Demographic features such as age and gender were not significantly different among the groups.White blood cell count,neutrophil percentage and platelet distribution width were significantly higher in Group?Ⅰ?compared to groupsⅡandⅢ(P<0.05).Diagnostically,the sensitivity,specificity and diagnostic accuracy were 73.1%,94.0%,and 78%for white blood cell count,70.0%,96.0%,and 76.0%for neutrophil percentage,29.5%,49.0%,and 34.0%for mean platelet volume,and 97.1%,93.0%,and 96.0%for platelet distribution width,respectively.The highest diagnostic accuracy detected was for platelet distribution width between Group?Ⅰ?and GroupⅢ(P<0.01).CONCLUSION:Platelet distribution width analysis can be used for diagnosis of acute appendicitis without requiring additional tests,thus reducing the cost and loss of time. | Bulent Dinc Alten Oskay Selcan Enver Dinc Bilge Bas Sabri Tekin | 2015 | World Journal of Gastroenterology2015，21，6： | 5 |
| 3 | MPV在慢性阻塞性肺疾病相关肺动脉高压中的潜在临床应用价值显示文摘目的观察血小板平均体积(MPV)在慢性阻塞性肺疾病(COPD)及COPD合并肺动脉高压(PH)患者中的临床应用价值。方法回顾性分析75例COPD稳定期患者、37例吸烟史匹配的健康体检者,通过心脏扇扫测量三尖瓣返流峰值流速估测肺动脉收缩压(PASP),将其分为3组,即:A组,COPD非PH组;B组,COPD合并PH组;C组,健康对照组。对比各组间MPV均值的差异,并统计MPV与心脏彩超各项指标的相关性。结果相对于C组,MPV在A组和B组升高(P<0.05),在B组升高更加明显(P<0.05)。MPV与左心室射血分数(EF)呈负相关,与右肺动脉直径正相关。结论 MPV在稳定期COPD合并肺动脉高压时升高明显,可作为监测COPD稳定期肺动脉压力及心肺功能受损的潜在指标。 | 何凌 吴萍 李萍 张丽萍 杨朝 耑冰 葛利军 吴昌归 | 2015 | 宁夏医学杂志2015，37，4： | 0 |
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