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| 1 | Type 2 diabetes is associated with a worse functional outcome of ischemic stroke显示文摘AIM: To assess whether ischemic stroke severity and outcome is more adverse in patients with type 2 diabetes mellitus(T2DM). METHODS: Consecutive patients hospitalized for acute ischemic stroke between September 2010 and June 2013 were studied prospectively(n = 482; 40.2% males, age 78.8 ± 6.7 years). T2 DM was defined as self-reported T2 DM or antidiabetic treatment. Stroke severity was evaluated with the National Institutes of Health Stroke Scale(NIHSS) score at admission. The outcome was assessed with the modified Rankin scale(m RS) score at discharge and with in-hospital mortality. Adverse outcome was defined as m RS score at discharge ≥ 2 or in-hospital death. The length of hospitalization was also recorded.RESULTS: T2 DM was present in 32.2% of the study population. Patients with T2 DM had a larger waist circumference, higher serum triglyceride and glucose levels and lower serum high-density lipoprotein cholesterol levels as well as higher prevalence of hypertension, coronary heart disease and congestive heart failure than patients without T2 DM. On the other hand, diabetic patients had lower low-density lipoprotein cholesterol levels and reported smaller consumption of alcohol than non-diabetic patients. At admission, the NIHSS score did not differ between patients with and without T2DM(8.7 ± 8.8 and 8.6 ± 9.2, respectively; P = NS). At discharge, the m RS score also did not differ between the two groups(2.7 ± 2.1 and 2.7 ± 2.2 in patients with and without T2 DM, respectively; P = NS). Rates of adverse outcome were also similar in patients with and without T2DM(62.3% and 58.5%, respectively; P = NS). However, when we adjusted for the differences between patients with T2 DM and those without T2 DM in cardiovascular risk factors, T2 DM was independently associated with adverse outcome [relative risk(RR) = 2.39; 95%CI: 1.21-4.72, P = 0.012]. Inhospital mortality rates did not differ between patients with T2 DM and those without T2DM(9.0% and 9.8%, respectively; P = NS). In multivariate analysis adjusting for the difference in cardiovascular risk factors between the two groups, T2 DM was again not associated with in-hospital death. CONCLUSION: T2 DM does not appear to affect ischemic stroke severity but is independently associated with a worse functional outcome at discharge. | Konstantinos Tziomalos Marianna Spanou Stella D Bouziana Maria Papadopoulou Vasilios Giampatzis Stavroula Kostaki Vasiliki Dourliou Maria Tsopozidi Christos Savopoulos Apostolos I Hatzitolios | 2014 | World Journal of Diabetes2014，5，6： | 15 |
| 2 | Admission delay is associated with worse surgical outcomes for elderly hip fracture patients:A retrospective observational study显示文摘BACKGROUND:The influence of surgical delay on mortality and morbidity has been studied extensively among elderly hip fracture patients.However,most studies only focus on the timing of surgery when patients have already been hospitalized,without considering pre-admission waiting time.Therefore,the present study aims to explore the infl uence of admission delay on surgical outcomes.METHODS:In this retrospective study,we recorded admission timing and interval from admission to surgery for included patient.Other covariates were also collected to control confounding.The primary outcome was 1-year mortality.The secondary outcomes were 1-month mortality,3-month mortality,ICU admission and postoperative pneumonia.We mainly used multivariate logistic regression to determine the effect of admission timing on postoperative outcomes.An additional survival analysis was also performed to assess the impact of admission delay on survival status in the fi rst year after operation.RESULTS:The proportion of patients hospitalized on day 0,day 1,day 2 after injury was 25.4%,54.7%and 66.3%,respectively.And 12.6%patients visited hospital one week later after injury.Mean time from admission to surgery was 5.2 days(standard deviation 2.8 days).Hospitalization at one week after injury was a risk factor for 1-year mortality(OR 1.762,95%CI 1.026–3.379,P=0.041).CONCLUSION:Admission delay of more than one week is signifi cantly associated with higher 1-year mortality.As a supplement to the current guidelines which emphasizes early surgery after admission,we also advocate early admission once patients get injured. | Wei He Yue-yang You Kai Sun Chen Xie Yue Ming Li-na Yu Feng-jiang Zhang Min Yan | 2020 | World Journal of Emergency Medicine2020，11，1： | 11 |
| 3 | Different prognostic association of systolic blood pressure at different time points with postdischarge events in patients hospitalized for decompensated heart failure显示文摘Background The association of systolic blood pressure(SBP) with mortality in heart failure(HF) patients is paradoxical, and the time points of baseline SBP are also different across prior studies. We hypothesized that the levels of SBP at admission and at discharge had different associations with postdischarge events. Methods The study population included patients hospitalized for decompensated HF in the Heart Failure Center of Fuwai Hospital from January 1, 2009 to December 31, 2014. The primary outcome was a composite of cardiovascular(CV) death and heart transplantation. Multivariate Cox proportional-hazards and restricted cubic spline analyses were used to assess the relationships between SBP at different time points and outcomes. Results In total, 2005 patients were included with a median follow-up of 48.4 months. The median age was 59 years, and 69.9% were male. Multivariate Cox analyses showed that compared with SBP < 105 mm Hg, higher SBP at admission was associated with better long-term primary outcome(105–119 mm Hg, HR = 0.764, P = 0.005;120-134 mm Hg, HR = 0.658, P < 0.001;≥ 135 mm Hg, HR = 0.657, P = 0.001). Patients whose discharge SBP was higher than 135 mm Hg had a similar primary outcome as those with SBP < 105 mm Hg(HR = 0.969, P = 0.867), and the results remained unchanged even after adjusting for admission SBP(HR = 1.235, P = 0.291). The results of restricted cubic spline analysis indicated similar associations. Conclusions Lower but not higher SBP at admission is associated with more CV deaths/heart transplantations(a reverse J-shaped curve). In contrast, there is a U-shaped association between discharge SBP and CV mortality/heart transplantation. | You-Nan YAO Rong-Cheng ZHANG Tao AN Qi ZHANG Xin-Ke ZHAO Jian ZHANG | 2019 | Journal of Geriatric Cardiology2019，16，9： | 5 |
| 4 | 急性缺血性卒中的心肌肌钙蛋白和N端前脑钠尿肽水平与临床预后无关 | Etgen T. Baum H. Sander K. Sander D. 赵正卿 | 2005 | 世界核心医学期刊文摘(神经病学分册)2005，0，7： | 4 |
| 5 | Admission Control with Elastic QoS for Video on Demand Systems显示文摘In network service systems, satisfying quality of service (QoS) is one of the main objectives. Admission control and resource allocation strategy can be used to guarantee the QoS requirement. Based on partially observable Markov decision processes (POMDPs), this paper proposes a novel admission control model for video on demand (VOD) service systems with elastic QoS. Elastic QoS is also considered in resource allocation strategy. Policy gradient algorithm is often available to find the solution of POMDP problems, with a satisfactory convergence rate. Through numerical examples, it can be shown that the proposed admission control strategy has better performance than complete admission control strategy. | Fu-Shou Lin 1 Bao-Qun Yin 1,2 Jing Huang 1 Xu-Min Wu 1 1 Key Lab of Anhui Network Communication System and Control, University of Science and Technology of China, Hefei 230027, China 2 National Network New Media Engineering Research Center, Institute of Acoustics, Chinese Academy of Science, Beijing 100190, China | 2012 | International Journal of Automation and computing2012，9，5： | 3 |
| 6 | Modeling and Analysis for Streaming Service Systems显示文摘The proliferation of streaming service system in various application areas gains increasing importance and also poses more challenges in the research of streaming service system. In this paper, we propose a novel dynamic model composed of a set of differential equations to describe the evolution of streaming service systems. And in the model, we focus on how the policies for admission control and peer selection influence on the system. We first introduce a flexible abstraction of streaming service systems. The abstraction is generally enough to capture the essences of streaming service systems with different structures, physical characteristics,software protocols and client behaviors. Then, by analyzing the state which is defined as the number of requests, a novel dynamic model is developed in microscopic scale to characterize the behaviors of streaming service systems. The model proposed in this paper demonstrates the interactions between clients and servers and also between different servers. The interactions are primarily influenced by the admission control policy and peer selection policy. Finally, some experiments are designed to verify the validation and reasonability of the model. | Hai-Peng Zhang Bao-Qun Yin Xiao-Nong Lu | 2014 | International Journal of Automation and computing2014，11，4： | 2 |
| 7 | Testing Patience显示文摘Children of migrant workers in many major cities are stillwaiting to enjoy equal educational opportunities Fifteen-year-old Zhan Haite thrust herself into the spotlight last year by calling for equal education opportunities for herself and fellow children of migrant workers. | Li Li | 2013 | Beijing Review2013，56，3： | 2 |
| 8 | 卒中护理供给是否存在不均衡性:城市内已注册卒中病例的分析 | McKevitt C. Coshall C. Tilling K. Wolfe C. 李一明 | 2005 | 世界核心医学期刊文摘(神经病学分册)2005，0，7： | 1 |
| 9 | 精神卫生立法需要着眼于未来(英文) | Ruth VINE Chee NG | 2012 | 上海精神医学2012，24，01X： | 1 |
| 10 | Analysis of clinical characteristics and risk factors of obstructive sleep apnea hypopnea syndrome with hypertension显示文摘Objective To study the risk factors contributing to the development of hypertension in patients with obstructive sleep apnoea hypopnea syndrome(OSAHS),and the clinical characteristics of OSAHS with hypertension.Methods A total of 2 397 OSAHS patients aged above 30years old and diagnosed by the sleep-disordered breath- | 莫晓云 | 2016 | China Medical Abstracts(Internal Medicine)2016，33，2： | 1 |
| 11 | Impact of thiopurines and anti-tumour necrosis factor therapy on hospitalisation and long-term surgical outcomes in ulcerative colitis显示文摘Ulcerative colitis(UC) is a chronic inflammatory condition affecting the large bowel and is associated with a significant risk of both requirement for surgeryand the need for hospitalisation. Thiopurines, and more recently, anti-tumour necrosis factor(a TNF) therapy have been used successfully to induce clinical remission. However, there is less data available on whether these agents prevent long-term colectomy rates or the need for hospitalisation. The focus of this article is to review the recent and pertinent literature on the long-term impact of thiopurines and a TNF on long-term surgical and hospitalisation rates in UC. Data from population based longitudinal research indicates that thiopurine therapy probably has a protective role against colectomy, if used in appropriate patients for a sufficient duration. a TNF agents appear to have a short term protective effect against colectomy, but data is limited for longer periods. Whereas there is insufficient evidence that thiopurines affect hospitalisation, evidence favours that a TNF therapy probably reduces the risk of hospitalisation within the first year of use, but it is less clear on whether this effect continues beyond this period. More structured research needs to be conducted to answer these clinically important questions. | Christopher Alexakis Richard CG Pollok | 2015 | World Journal of Gastrointestinal Surgery2015，7，12： | 1 |
| 12 | Prognostic value of circulating catestatin levels for in-hospital heart failure in patients with acute myocardial infarction显示文摘Objective To determine whether circulating level of catestatin(CST) could provide prognostic information independently of conventional risk markers for the development of in-hospital heart failure in patients with ST-segment elevation myocardial infarction(STEMI). | 冀磊 | 2013 | China Medical Abstracts(Internal Medicine)2013，30，1： | 1 |
| 13 | New evidence-based clinical practice guideline timely supports hospital infection control of coronavirus disease 2019显示文摘The outbreak of the coronavirus disease 2019(COVID-19,previously named 2019-nCoV)has become a serious public health situation in China.1,2 As of February 18,2020,over 70000 patients were diagnosed with COVID-19,including thousands of healthcare providers.Chinese hospitals,especially those in Hubei Province,are facing increasing admission of infected patients,and the epidemics involve hospitals across all levels. | Sheyu Li Zhiyong Zong Xin Sun Weimin Li | 2020 | Precision Clinical Medicine2020，3，1： | 1 |
| 14 | Usefulness of the CONUT index upon hospital admission as a potential prognostic indicator of COVID-19 health outcomes显示文摘Background:In-hospital mortality in patients with coronavirus disease 2019(COVID-19)is high.Simple prognostic indices are needed to identify patients at high-risk of COVID-19 health outcomes.We aimed to determine the usefulness of the CONtrolling NUTritional status(CONUT)index as a potential prognostic indicator of mortality in COVID-19 patients upon hospital admission.Methods:Our study design is of a retrospective observational study in a large cohort of COVID-19 patients.In addition to descriptive statistics,a Kaplan-Meier mortality analysis and a Cox regression were performed,as well as receiver operating curve(ROC).Results:From February 5,2020 to January 21,2021,there was a total of 2969 admissions for COVID-19 at our hospital,corresponding to 2844 patients.Overall,baseline(within 4 days of admission)CONUT index could be scored for 1627(57.2%)patients.Patients’age was 67.3±16.5 years and 44.9%were women.The CONUT severity distribution was:194(11.9%)normal(0-1);769(47.2%)light(2-4);585(35.9%)moderate(5-8);and 79(4.9%)severe(9-12).Mortality of 30 days after admission was 3.1%in patients with normal risk CONUT,9.0%light,22.7%moderate,and 40.5%in those with severe CONUT(P<0.05).An increased risk of death associated with a greater baseline CONUT stage was sustained in a multivariable Cox regression model(P<0.05).An increasing baseline CONUT stage was associated with a longer duration of admission,a greater requirement for the use of non-invasive and invasive mechanical ventilation,and other clinical outcomes(all P<0.05).The ROC of CONUT for mortality had an area under the curve(AUC)and 95%confidence interval of 0.711(0.676-0746).Conclusion:The CONUT index upon admission is potentially a reliable and independent prognostic indicator of mortality and length of hospitalization in COVID-19 patients. | Adrian K.Bengelloun Guillermo J.Ortega Julio Ancochea Ancor Sanz-Garcia Diego A.Rodriguez-Serrano Guillermo Fernandez-Jimenez Rosa Giron Elena Avalos Joan B.Soriano J.Ignacio de Ulibarri | 2022 | Chinese Medical Journal2022，，2： | 0 |
| 15 | The effects of real-time continuous glucose monitoring on oxidative stress and mortality in critically ill patients显示文摘Objective To evaluate the effects of real-time continuous glucose monitoring(RT-CGM) system on oxidative stress and mortality in critically ill patients and to explore the correlation between glucose index,oxidative stress and mortality. Methods 123 selected cases | 钱武强 | 2013 | China Medical Abstracts(Internal Medicine)2013，30，1： | 0 |
| 16 | Risk Stratification with Serum Cardiac Troponin I in Acute Myocardial Infarction on Admission显示文摘Objective To assess the prognostic significance of serum cardiac troponin I (cTnI) concentration in patients with acute myocardial infarction on admission. Methods Serum samples of 108 patients with established AMI were collected on admission for measuring cTnI and were grouped according to the intervals between the onset of chest pain and admission. Results In each of these groups, the serum cTnI concentrations in patients died after admission were significantly higher than those who survived (all P<0.05). Conclusions A higher serum cTnI concentration on admission in patients with AMI was associated with an increased risk of subsequent cardiac death during hospitalization. | 张铸 苏恩本 张寄南 杨志健 曹克将 马文珠 | 2001 | Journal of Nanjing Medical University2001，15，2： | 0 |
| 17 | GEDVI and PPV predict fluid responsiveness in patients with ALI secondary to septic shock显示文摘Objective To evaluate PICCO(pulse indicator continuous cardiac output)to predict fluid responsiveness in patients with acute lung injury secondary to septic shock.Methods We conducted a prospective study on 42 patients with acute lung injury secondary to septic shock.global end-diastolic volume index(GEDVI),pulse pressure variation(PPV),stroke volume variation(SVV), | 汪华玲 | 2014 | China Medical Abstracts(Internal Medicine)2014，31，2： | 0 |
| 18 | ECIEN-2020 study:the effect of COVID-19 on admissions for non-COVID-19 diseases显示文摘Background The pandemic caused by severe acute respiratory coronavirus 2(SARS-CoV-2)has had great effects on health systems worldwide,not only in relation to coronavirus disease 2019(COVID-19)cases but also affecting patients with other pathologies.Methods ECIEN-2020 is an observational study conducted in a tertiary referral hospital in Navarra,Spain.It describes the effects of COVID-19 pandemic and the preventive measures adopted,in pediatric admissions for non-COVID-19 diseases.Admissions during March-June 2020(first wave of the COVID-19 pandemic in Spain)are described and compared with the same quarter in 2019.A sub-analysis was performed delving into epidemiology.Patient characteristics(age,sex,past medical history),disease characteristics(symptoms,duration of symptoms,previous consultation in Primary Care Health Center),and admission characteristics(place and average stay)were analyzed.Results A 33% reduction in the number of pediatric hospital admissions was observed,decreasing from 529 hospitaliza-tions in 2019 to 353 in 2020(P<0.001).This highlights a 48% reduction in patients admitted for pulmonary diseases.There were no significant changes in average hospital-stay,percentage of intensive care unit admissions,or in admissions for other reasons.Percentage of patients admitted among those seen in the emergency department rose from 5.1%in 2019 to 10.9% in 2020,whereas the total number of consultations in the emergency department decreased by 68%.Conclusion The pandemic and the measures adopted due to SARS-CoV-2 have significantly decreased pediatric admissions for non-COVID-19 diseases,especially due to a reduction in the hospitalization for respiratory diseases. | Beatriz Ramos-Lacuey Mercedes Herranz Aguirre Clara Calderón Gallego Andrea Ilundain López de Munain Eva Gembero Esarte Laura Moreno-Galarraga | 2021 | World Journal of Pediatrics2021，17，1： | 0 |
| 19 | Prognostic significance of early lactate clearance rate for severe acute respiratory failure patients on extracorporeal membrane oxygenation显示文摘Objective To investigate the prognostic significanceof early lactate clearance rate for severe acute respiratory failure patients on extracorporeal membrane oxygenation(ECMO).Methods Forty-three patients with severe acute respiratory failure supported by venous-venous(v-v)ECMO were enrolled from January 2007 to January 2013.Arterial blood lactate at pre-ECMO support(0 h)and | 臧芝栋 | 2014 | China Medical Abstracts(Internal Medicine)2014，31，2： | 0 |
| 20 | 资讯显示文摘中国摄协颁布新版个人会员入会细则China Photographers Association issues new version rules for personal admission中国摄影家协会颁布新版个人会员入会细则,新修订的《中国摄影家协会个人会员入会细则》经中国摄影家协会第八届主席团第二次会议上审议通过,并于7月1日起施行。本次入会细则的修订,将条款表述方式由文本式改为表格式,申请人的业绩条件为积分制,分值计算由原来的4分制变为10分制——积分达10分以上(含10分),同时其中须有4分以上为中国摄协或所属部门相关条件者,可以提出入会申请。新的入会细则更加开放、更加严格、更加细化,便于申请人和审核人准确掌握和把控。 | | 2013 | 走向世界2013，0，32： | 0 |
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