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| 1 | Phase stability in high entropy alloys:Formation of solid-solution phase or amorphous phase | Sheng GUO C.T. LIU | 2011 | Progress in Natural Science:Materials International2011,21,6: | 91 |
| 2 | Advanced gastric cancer:Current treatment landscape and future perspectives显示文摘Gastric cancer currently ranks fourth in cancer-related mortality worldwide. In the western world, it is most often diagnosed at an advanced stage, after becoming metastatic at distant sites. Patients with advanced disease(locally advanced or metastatic) have a somber prognosis, with a median overall survival of 10-12 mo, and palliative chemotherapy is the mainstay of treatment. In recent years, novel approaches using inhibition of human epidermal growth factor receptor 2(HER2) have demonstrated significant improvements in progression-free and overall survival, compared with chemotherapy alone, in first-line treatment of patients with overexpression of HER2. In addition, both second-line chemotherapy and treatment with the vascular endothelial growth factor receptor-inhibitor ramucirumab demonstrated significant benefits in terms of overall survival, compared with best supportive care, in randomized studies. Moreover, ramucirumab in combination with chemotherapy demonstrated further significant benefits in terms of progression-free and overall survival, compared with chemotherapy alone, in second-line treatment for patients with metastatic gastric cancer. A recently published molecular classification of gastric cancer is expected to improve patient stratification and selection for clinical trials and provide a roadmap for future drug development. Nevertheless, despite these developments the prognosis of patients with advanced gastric cancer remains poor. In this review we discuss current standards of care and outline major topics of drug development in gastric cancer. | Antonia Digklia Anna Dorothea Wagner | 2016 | World Journal of Gastroenterology2016,22,8: | 108 |
| 3 | Entransy dissipation minimization for liquid-solid phase change processes显示文摘The liquid-solid phase change process of a simple one-dimensional slab is studied in this paper.By taking entransy dissipation minimization as optimization objective,the optimal external reservoir temperature profiles are derived by using optimal control theory under the condition of a fixed freezing or melting time.The entransy dissipation corresponding to the optimal heat exchange strategies of minimum entransy dissipation is 8/9 of that corresponding to constant reservoir temperature operations,which is independent of all system parameters.The obtained results for entransy dissipation minimization are also compared with those obtained for the optimal heat exchange strategies of minimum entropy generation and constant reservoir temperature operations by numerical examples.The obtained results can provide some theoretical guidelines for the choice of optimal cooling or heating strategy in practical liquid-solid phase change processes. | XIA ShaoJun,CHEN LinGen & SUN FengRui Postgraduate School,Naval University of Engineering,Wuhan 430033,China | 2010 | Science China(Technological Sciences)2010,53,4: | 41 |
| 4 | 分散固相萃取-高效液相色谱法快速检测猕猴桃中的氯吡脲显示文摘建立了高效液相色谱快速检测猕猴桃中氯吡脲残留的方法。试样经乙腈提取、丙基乙二胺(PSA)分散固相萃取(DSPE)净化后在C18柱上以乙腈-0.01mol/L磷酸水溶液(体积比为35:65)为流动相进行分离,在260nm波长下检测。氯吡脲的检出限为0.005mg/kg,在0.05~10.00mg/L时线性关系良好(r=1.000)。试样在0.05,0.60,1.20mg/kg三个添加水平的回收率为82.0%~112.0%,相对标准偏差(RSD)(n=5)为2.41%。该方法简便快速,准确灵敏,适合大批量样品的快速处理。 | 胡江涛 盛毅 方智 金晶 何开蓉 | 2007 | 色谱2007,25,3: | 48 |
| 5 | 顶空固相微萃取气质联用检测鸭肉挥发性风味成分显示文摘采用顶空固相微萃取气质联用(Headspacesolidphasemicroextractioncombinedwithgaschromatgraphymassspectrometry,HS-SPME-GC-MS)分析检测了生鸭肉、烘烤鸭肉、水煮鸭脯肉和鸭腿肉的挥发性香气成分。共检测到55种风味化合物,其中烃类10种、酮类8种、醇类8种、醛类12种、酸类5种、酯类2种、含硫含氮及杂环化合物10种。 | 刘源 周光宏 徐幸莲 刘扬岷 王利平 袁身淑 | 2005 | 江苏农业学报2005,21,2: | 39 |
| 6 | Consolidated and emerging inflammatory markers in coronary artery disease显示文摘Coronary artery disease is an event of atherosclerosis characterized by a chronic vascular inflammation. Risk factors like obesity, diabetes mellitus, hypertension,smoking, hypercholesterolemia and positive family history sometimes are not sufficiently adequate to the enhancement of cardiovascular risk assessment. In the past years numerous biomarkers, like C reactive protein,cytokines and adhesion molecules, have been observed to be related to adverse cardiovascular prognosis. Recently,several studies found an association among inflammatory biomarkers and cardiovascular diseases suggesting their utility to identify the risk of an acute ischemic event and the detection of vulnerable plaques. The emerginginflammatory markers are well divided for diagnosis and prognosis and plaque instability of coronary artery disease. Some of them, the lectin-like oxidized low density lipoprotein receptor-1 can be important both in diagnosis and in the evaluation of plaque instability, other are inserted in the above reported classification. The emerging inflammatory markers in acute-phase include amyloid A, fibrinogen and pentraxin 3 while myeloperoxidase, myeloid-related protein 8/14 and pregnancy-associated plasma protein-A are recognize markers of plaque instability. Lastly, some studies demonstrated that circulating mi RNAs are involved in coronary artery disease, acute myocardial infarction and heart failure. | Valter Lubrano Silvana Balzan | 2015 | World Journal of Experimental Medicine2015,5,1: | 29 |
| 7 | Analytical method for softness abrasive flow field based on discrete phase model显示文摘Aiming at the problem of difficult contact finishing for mini structural surface in course of mould manufacturing,a new no-tool precision machining method based on soft abrasive flow machining (SAFM) was proposed. It allocated restrained component near surface machined,constituted restrained abrasive flow passage,and made the surface become a segment of passage wall. It could control turbulence abrasive flow in restrained passage,realize micro cutting for passage wall,and utilize the irregular motion of abrasive flow to eliminate the mono-directional marks on machined surfaces,and the precision could reach the specular level. A two-phase dynamic model of abrasive flow oriented to SAFM combined with discrete phase model (DPM) was established,the law of two-phase flow motion and the related physical parameters was obtained by corresponding numerical simulation method,and the mechanism of precision machining in SAFM was discussed. Simulation results show that the abrasive flow machining process mainly appears as translation of ablating location with the influence by granular pressure,and as the variation of machining efficiency with the influence by near-wall particle velocity. Thus via control of the inlet velocity and its corresponding machining time,it is supposed to work out the machining process according to the machining requirements by using the Preston equation to seek the relationship among velocity,pressure and material removing rate. By tracking near-wall particles,it can be confirmed that the movement of near-wall abrasive particles is similar to stream-wise vortices. The cutting traces on workpiece surfaces assume disorderly arrangement,so the feasibility of the SAFM method can be reaffirmed. | JI ShiMing1,2, XIAO FengQing1,2 & TAN DaPeng1,2 1Key Laboratory of Special Purpose Equipment and Advanced Manufacturing Technology, (Zhejiang University of Technology), Ministry of Education, Hangzhou 310014, China 2Key Laboratory of Special Purpose Equipment and Advanced Manufacturing Technology of Zhejiang Province, Hangzhou 310014, China | 2010 | Science China(Technological Sciences)2010,53,10: | 28 |
| 8 | Green chemistry of chromate cleaner production显示文摘Research topics and methods of green chemistry in chromate production are introduced in this paper . New original green chemical process of the heterogeneous reaction and separation system of liquid phase oxidation of chromite in molten salt of sodium hydroxide-one way separation in high concentration medium-metastable phase separation-carbonate recycle conversion has been developed. The green commercial process for comprehensive utilization of mineral resources-reactant recycle inside the process-zero emission was established . | 张懿 李佐虎 齐涛 王志宽 郑诗礼 | 1999 | Chinese Journal of Chemistry1999,17,3: | 27 |
| 9 | Dielectric metasurfaces for complete and independent control of the optical amplitude and phase显示文摘Metasurfaces are optically thin metamaterials that promise complete control of the wavefront of light but are primarily used to control only the phase of light.Here,we present an approach,simple in concept and in practice,that uses meta-atoms with a varying degree of form birefringence and rotation angles to create high-efficiency dielectric metasurfaces that control both the optical amplitude and phase at one or two frequencies.This opens up applications in computer-generated holography,allowing faithful reproduction of both the phase and amplitude of a target holographic scene without the iterative algorithms required in phase-only holography.We demonstrate all-dielectric metasurface holograms with independent and complete control of the amplitude and phase at up to two optical frequencies simultaneously to generate two-and three-dimensional holographic objects.We show that phaseamplitude metasurfaces enable a few features not attainable in phase-only holography;these include creating artifactfree two-dimensional holographic images,encoding phase and amplitude profiles separately at the object plane,encoding intensity profiles at the metasurface and object planes separately,and controlling the surface textures of three-dimensional holographic objects. | Adam C.Overvig Sajan Shrestha Stephanie C.Malek Ming Lu Aaron Stein Changxi Zheng Nanfang Yu | 2019 | Light(Science & Applications)2019,8,1: | 27 |
| 10 | Kinematics Modeling and Experiments of Pectoral Oscillation Propulsion Robotic Fish显示文摘A robotic fish driven by oscillating fins, 'Cownose Ray-I', is developed, which is in dorsoventrally flattened shape withouta tail. The robotic fish is composed of a body and two lateral fins. A three-factor kinematic model is established and used in thedesign of a mechanism. By controlling the three kinematic parameters, the robotic fish can accelerate and maneuver. Forwardvelocity is dependent on the largest amplitude and the number of waves in the fins, while the relative contribution of fin beatfrequency to the forward velocity of the robotic fish is different from the usual result. On the other hand, experimental results onmaneuvering show that phase difference has a stronger effect on swerving than the largest amplitude to some extent. In addition,as propulsion waves pass from the trailing edge to the leading edge, the robotic fish attains a backward velocity of 0. 15 m·s-1. | Shao-bo Yang,Jing Qiu,Xiao-yun HanInstitute of Mechatronical Engineering and Automatization,National University of Defense Technology,Changsha 410073,P.R.China | 2009 | Journal of Bionic Engineering2009,6,2: | 25 |
| 11 | 固相萃取-气相色谱-质谱法同时测定水中9种药品及个人护理用品显示文摘采用固相萃取-气相色谱-质谱联用技术,建立了水体中9种药品及个人护理用品(水杨酸、萘普生、布洛芬、对乙酰氨基酚、降固醇酸、三氯生、双氯酚酸、酮洛芬和双酚 A)的定量分析方法。水样品经稀盐酸调节至 pH =3后,采用 Oasis HLB 固相萃取小柱进行富集净化;选用三甲基氢氧化硫( TMSH)为衍生化试剂,在常温条件下对目标物进行快速甲基化;以气相色谱-质谱法选择离子监测模式(GC-MS-SIM)进行检测,由2,4,5-涕丙酸为内标进行定量分析。本实验分别对固相萃取和衍生化等前处理条件进行了系统的研究。在优化的实验条件下,方法的回收率为50.7~115.4%,相对标准偏差均不高于10%,检出限为0.03~0.30μg / L,定量限为0.15~1.50μg / L。利用该方法对东莞市某农田灌溉水进行了分析,4种目标物在样品中有检出,最大质量浓度范围为0.176~0.998μg / L。结果表明该方法操作简便,灵敏可靠。 | 贾妍艳 谭建华 徐晨 汤嘉骏 王赢利 解启来 | 2014 | 色谱2014,32,3: | 25 |
| 12 | Thermodynamics and kinetics of phase transformation in rare earth–magnesium alloys:A critical review显示文摘Magnesium and its alloys are significant superior metallic materials for structural components in automobile and aerospace industries due to their excellent physicomechanical properties.The Mg–rare earth(RE)systems have attracted great interests because RE additions can improve both the deformability and the strength of Mg alloys through solid solution strengthening and precipitation hardening mechanisms.This paper focuses on the interface stability,together with thermodynamics and kinetics of nucleation and growth of the key phases and matrix phases in Mg–RE alloys.In this paper,the theory and recent advances on Mg–RE alloys,especially for the interface stability,thermodynamics and kinetics of nucleation and growth of the key phases and matrix phases,together with their relationships with micro-structures,and macroscopic properties,are reviewed.By combining the thermodynamics/kinetics integrated simulations with various advanced experimental techniques,“reverse”design of Mg–RE alloys starting from the target service performance is put forward as a kind of scientific paradigm with rational design. | Qun Luo Yanlin Guo Bin Liu Yujun Feng Jieyu Zhang Qian Li Kuochih Chou | 2020 | Journal of Materials Science & Technology2020,44,9: | 26 |
| 13 | Large and meso-α scale characteristics of intense rainfall in the mid- and lower reaches of the Yangtze River显示文摘Meteorological conditions associated with intense rainfall and great floods over mid- and lower reaches of Yangtze River are studied by analyzing the large-, synoptic-and meso-a-scale circulation systems for 1991, 1996 and 1998. It is found that the advance and retreat of subtropical high over the West Pacific, the monsoon moisture surge from the South China Sea, cold air outbreak over mid- and high-latitudes, and the meso-α scale systems (250-2500 km) from the Tibetan Pleateau as well, are responsible for intense rainfall over the Yangtze River Valley. The persistent and heavy rains and great floods over the Yangtze River Valley occurred when all these four systems are synergetic or in phase lock. | Shunli Zhang Shiyan Tao Qingyun Zhang Jie Wei | 2002 | Chinese Science Bulletin2002,47,9: | 22 |
| 14 | The Aging Feature of Al-L-Cu-Mg-Zr Alloy Containing Sc显示文摘The aging behaviors of Al 1.42%Li 2.41%Cu 0.93%Mg 0.073%Zr 0.17%Sc(mass fraction, the same below) alloy at room temperature, 160 ℃ , and 160 ℃ after 8% pre deformation were studied respectively by hardness measurement. The microstructure of the alloy in various aging conditions was observed by TEM. The results show that the main precipitations of the alloy in quenching condition are the particles containing Sc and Zr which have certain coherent relation with the matrix. Addition of Sc in Al Li Cu Mg Zr alloy will be favorable to promoting precipitation. The particles can serve as preferred nucleation sites for δ′ phases which accelerate the aging hardening rate at initial aging. The main hardening phases of the alloy aged at 160 ℃ are δ′ and δ′/β′ composite precipitates. The size of the composite precipitates is very small (nanometer size). The composite precipitates will preclude efficiently the formation concentrative slip location and will improve the mechanical properties of the alloy. S′ phase will occur in the alloy aged at 160 ℃ after 8% pre deformation. It is found that 8% pre deformation has no obvious influence on the precipitation of the composite phase. | TAN Cheng yu,ZHENG Zi qiao,XIA Chang qing,LIANG Ying (Department of Materials Science and Engineering, Central South University of Technology, Changsha 410083, China) | 2000 | Journal of Central South University2000,12,2: | 22 |
| 15 | DEVELOPMENT OF INCONEL~ ALLOY 783,A LOW THERMAL EXPANSION,CRACK GROWTH RESISTANT SUPERALLOY显示文摘DEVELOPMENTOFINCONEL~ALLOY783,ALOWTHERMALEXPANSION,CRACKGROWTHRESISTANTSUPERALLOYJ.H.Thndermann(IncoAlloysInternational,Inc.... | J.H.Thndermann(Inco Alloys International, Inc., Huntington, WV 25705, USA ) | 1996 | Acta Metallurgica Sinica(English Letters)1996,9,6: | 23 |
| 16 | 固相萃取-超高效液相色谱-电喷雾串联质谱法同时测定地表水中16种全氟有机化合物显示文摘建立了固相萃取-超高效液相色谱-电喷雾串联三重四极杆质谱联用技术分析水中16种全氟有机化合物的高通量检测方法。样品经 WAX 固相萃取柱富集和净化后,采用 Waters ACQUITY UPLCTM BEH C18色谱柱,含2 mmol/L乙酸铵的甲醇和含2 mmol/L乙酸铵的水作为流动相进行梯度洗脱,质谱采用电喷雾负离子电离,多反应监测模式检测。16种全氟有机化合物在0.5~100μg/L或1.0~100μg/L 浓度范围内线性关系良好,相关系数为0.9987~0.9999,方法的检出限为0.06~0.46 ng/L;高、中、低3个添加水平的回收率为67.6%~103%,相对标准偏差为2.94%~12.0%。结果表明,该方法灵敏、准确且检测范围广,分析速度快,是一种适于实际水样中全氟有机化合物检测分析的方法。 | 张明 唐访良 俞雅雲 陈峰 徐建芬 叶永根 | 2014 | 色谱2014,32,5: | 22 |
| 17 | 液相色谱-串联质谱同时测定禽肉组织中盐酸金刚烷胺、盐酸金刚乙胺、地塞米松、替米考星及喹乙醇代谢物的残留量显示文摘建立了同时测定禽肉组织中盐酸金刚烷胺、盐酸金刚乙胺、地塞米松、替米考星及喹乙醇代谢物残留量的液相色谱-串联质谱分析方法.样品用2 mol/L氢氧化钠溶液水解,盐酸调节pH值后,以乙腈作为提取溶剂,经C18固相萃取柱净化.各待测物分别经0.1%甲酸甲醇溶液和氨化甲醇(0.1%氨水)洗脱,Phe-nomenex Kinetex C1s(100 mm×4.6 mm,2.6 μm)色谱柱进行分离,采用0.1%甲酸(含5 mmol/L乙酸铵)-甲醇作流动相,梯度洗脱,串联质谱法对5种药物含量进行测定.结果表明,5种药物在2 ~ 100 μg/L范围内线性关系良好,相关系数为0.996 2 ~0.999 8.在加标浓度为5~50 μg/kg的禽肉组织中,这5种药物的加标回收率为73.7% ~92.3%,相对标准偏差(n=5)为3.9% ~ 16.6%,检出限为0.2~ 3.0 μg,/kg,定量下限为0.7~ 10 μg/kg.方法快速、简便、经济实用,符合法规要求,可满足日常检测的需要. | 易锡斌 裘立群 刘世琦 黄晓琴 | 2015 | 分析测试学报2015,34,3: | 22 |
| 18 | 新疆西南天山木扎尔特河一带低压泥质麻粒岩岩石学特征、独居石U-Th-Pb定年及其地质意义显示文摘古南天山洋闭合过程中,由于洋壳俯冲产生的岛弧岩浆作用加热大陆地壳,在新疆西南天山木扎尔特一带形成了一套低压高温泥质麻粒岩相变质岩石。本文用Theriak-Domino热力学软件对该套岩石中的堇青石榴夕线石黑云母片麻岩和含夕线石堇青石榴黑云母片麻岩进行了岩石学相平衡计算研究,得到它们峰期变质的温压条件分别是:T=630~674℃,P=5.2~5.5kbar和T=645~684℃,P=5.4~5.7kbar。并采用独居石Th-U-Pb电子探针定年方法,对样品WQ006中的3颗独居石进行了原位年龄测定(38个分析点),得到2组等时线年龄,分别是376±8Ma和280±8Ma(2σ)。结合独居石的岩相学特征,提出了新疆西南天山低压高温麻粒岩相峰期变质作用的时代为280±8Ma,而376±8Ma(2σ)可能为原沉积岩的原岩/成岩年龄。表明西南天山洋壳开始俯冲发生在晚古生代,进一步证明了西南天山造山带俯冲碰撞发生在晚二叠纪之后的观点。 | 苟龙龙 张立飞 G0U | 2009 | 岩石学报2009,25,9: | 21 |
| 19 | The precipitation strengthening behavior of Cu-rich phase in Nb contained advanced Fe-Cr-Ni type austenitic heat resistant steel for USC power plant application | Cheng-yu Chi a, Hong-yao Yu b, Jian-xin Dong b, Wen-qing Liu c, Shi-chang Cheng d, Zheng-dong Liu d, Xi-shan Xie b a School of Metallurgical and Ecological Engineering, University of Science & Technology Beijing, Beijing 100083, China b School of Materials Science and Engineering, University of Science & Technology Beijing, Beijing 100083, China c Instrumental Analysis & Research Center, Shanghai University, Shanghai 200444, China d Central Iron and Steel Research Institute, Beijing 100081, China | 2012 | Progress in Natural Science:Materials International2012,22,3: | 20 |
| 20 | 适用于电网不平衡时的广义积分器锁相环设计显示文摘为准确快速检测出电网电压的幅值、相位和频率,在分析对称分量法及单同步坐标系锁相环基本原理的基础上,提出了广义积分器锁相环的设计方法。这种方法在αβ坐标系下对电网电压进行正、负分序,进而锁定正序电压的相位和频率。并且使用Matlab/Simulink环境分别对单同步坐标系锁相环和基于广义积分器锁相环进行仿真研究,仿真结果表明广义积分器锁相环在电网不平衡时能够准确提取电网信号的幅值、相位和频率,频率自适应性良好且对低次谐波有一定的抑制作用。 | 胡应占 郭素娜 | 2014 | 电力系统保护与控制2014,42,11: | 20 |