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| 1 | Clinical application of DNA ploidy to cervical cancer screening: A review显示文摘Screening for cervical cancer with DNA ploidy assessment by automated quantitative image cytometry has spread throughout China over the past decade and now an estimated 1 million tests per year are done there. Compared to conventional liquid based cytology, DNA ploidy has competitive accuracy with much higher throughput per technician. DNA ploidy has the enormous advantage that it is an objective technology that can be taught in typically 2 or 3 wk, unlike qualitative cytology, and so it can enable screening in places that lack sufficient qualified cytotechnologists and cytopathologists for conventional cytology. Most papers on experience with application of the technology to cervical cancer screening over the past decade were published in the Chinese language. This review aims to provide a consistent framework for analysis of screening data and to summarize some of the work published from 2005 to the end of 2013. Of particular interest are a few studies comparing DNA ploidy with testing for high risk human papilloma virus(hrH PV) which suggest that DNA ploidy is at least equivalent, easier and less expensive than hrH PV testing. There may also be patient management benefits to combining hr HPV testing with DNA ploidy. Some knowledge gaps are identified and some suggestions are made for future research directions. | David Garner | 2014 | World Journal of Clinical Oncology2014，5，5： | 43 |
| 2 | Detection of serum tumor markers in the diagnosis and treatment of patients with pancreatic cancer显示文摘BACKGROUND: Although a variety of tumor markers areavailable for diagnosis of pancreatic cancer, their sensitivityand specificity have not yet been ideal. The aims of thisstudy was to detect a panel of serum tumor markers and toevaluate their significance in the diagnosis and prognosis ofpancreatic cancer patients.METHODS: Eight serum tumor markers including AFP,CEA, CA-50, CA72-4, CA-125, CA153, CA19-9 and CA242were detected in 129 patients with pancreatic cancer by usingchemiluminescence immunoassay, immunofluorescence as-say and immunoradiometric assay, respectively. The levelsof these markers were compared in 99 patients with non-pancreatic malignant tumor, 63 patients with other benigndiseases, and 27 patients with pancreatic cancer after pan-createctomy.RESULTS: Among the 8 tumor markers, CA19-9, CA242,CA-50, and CA72-4 were more sensitive in the diagnosis ofpancreatic cancer. Parallel combined testing could increasethe diagnostic sensitivity to 89.2%, and serial combined exa-mination could increase the diagnostic specificity to 92.3%.The serum tumor markers levels were decreased significant-ly after radical tumor resection.CONCLUSIONS: Serum CA19-9, CA242, CA-50, andCA72-4 are the preferred tumor markers to be used in thediagnosis and follow-up of operated cases of pancreaticcancer. Testing of a panel of multiple serum tumor mark-ers may increase the sensitivity and specificity in the diag-nosis of pancreatic cancer. | Xiao-Ting Jiang, Hou-Quan Tao and Shou-Chun Zou Clinical Medical Laboratory and Depart-ment of Surgery , Zhejiang Provincial People’ sHospital, Hangzhou 310014 , China | 2004 | Hepatobiliary & Pancreatic Diseases International2004，3，3： | 35 |
| 3 | 草莓病毒病及其脱毒与检测技术研究进展显示文摘介绍了在草莓病毒病为害特点及其作用机理。综述了热处理、茎尖培养、花药培养等草莓脱毒技术和运用指示植物、血清学和分子生物学等检测技术。介绍了草莓无毒苗的栽培效果。 | 肖君泽 黄益鸿 姜放军 邓沛怡 阎珂 | 2010 | 江西农业学报2010，22，8： | 24 |
| 4 | A Survey of Testing for 5G:Solutions,Opportunities,and Challenges显示文摘With the development of wireless communication technology,the fifth generation mobile communications system(5 G) emerges at a historic moment and devotes itself to open the curtain of the information age.Recently,in order to satisfy the requirement of different applications,various advanced 5 G technologies have been developed in full swing.However,before applying these 5 G related technologies in practical systems,effective testing methods are needed to evaluate these technologies in a real,comprehensive,rapid and flexible manner.However,the testing methods are faced with new challenges along with the continuous development of the new 5 G technologies.In this paper,we present a survey of 5 G testing,including solutions and opportunities.In particular,two cases are considered,i.e.,channel modelling and overthe-air(OTA) testing of antenna systems.Specifically,a non-stationary channel model is proposed to characterize and test massive multiple-input multiple-output(MIMO) channel.In addition,we propose two probe subset selection algorithms for three-dimensional(3 D) OTA testing,which minimizes the number of probe antennas while ensuring the accuracy of the target channel emulation.Finally,future research directions and challenges on 5 G testing are given. | Ping Zhang Xiaoli Yang Jianqiao Chen Yuzhen Huang | 2019 | China Communications2019，16，1： | 21 |
| 5 | Rapid seismic analysis methodology for in-service wind turbine towers显示文摘The wind energy industry has been growing rapidly during the past decades.Along with this growth,engineering problems have gradually emerged in the wind power industry,including those related to the structural reliability of turbine towers.This study proposes a rapid seismic analysis methodology for existing wind turbine tower structures.The method is demonstrated and validated using a case study on a 1.5 MW tubular steel wind turbine tower.Three finite element(FE)models are developed first.Field tests are conducted to obtain the turbine tower's vibrational characteristics.The tests include(1) remotely measuring the tower vibration frequencies using a long range laser Doppler Vibrometer and(2) monitoring the tower structural vibration by mounting accelerometers along the height of the tubular structure.In-situ measurements are used to validate and update the FE models of the wind turbine tower.With the updated FE model that represents the practical structural conditions,seismic analyses are performed to study the structural failure,which is defined by the steel yielding of the tubular tower.This research is anticipated to benefit the management of the increasing number of wind energy converters by providing an understanding of the seismic assessment of existing tubular steel wind turbine towers. | Dai Kaoshan Huang Yichao Gong Changqing Huang Zhenhua Ren Xiaosong | 2015 | Earthquake Engineering and Engineering Vibration2015，14，3： | 20 |
| 6 | HER2 testing in gastric cancer: An update显示文摘Human epidermal growth factor receptor 2(HER2) overexpression is increasingly recognized as a frequent molecular abnormality in gastric and gastroesophageal cancer. With the recent introduction of HER2 molecular targeted therapy for patients with advanced gastric cancer, determination of HER2 status is crucial in order to select patients who may benefit from this treatment. This paper provides an update on our knowledge of HER2 in gastric and gastroesophageal cancer, including the prognostic relevance of HER2, the key differences between HER2 protein expression interpretation in breast and gastric cancer, the detection methods and the immunohistochemistry scoring system. | Lucas Faria Abrahao-Machado Cristovam Scapulatempo-Neto | 2016 | World Journal of Gastroenterology2016，22，19： | 19 |
| 7 | Fiducial inference in the pivotal family of distributions显示文摘In this paper a family, called the pivotal family, of distributions is considered.A pivotal family is determined by a generalized pivotal model. Analytical results show that a great many parametric families of distributions are pivotal. In a pivotal family of distributions a general method of deriving fiducial distributions of parameters is proposed. In the method a fiducial model plays an important role. A fiducial model is a function of a random variable with a known distribution, called the pivotal random element, when the observation of a statistic is given.The method of this paper includes some other methods of deriving fiducial distributions. Specially the first fiducial distribution given by Fisher can be derived by the method. For the monotone likelihood ratio family of distributions, which is a pivotal family, the fiducial distributions have a frequentist property in the Neyman-Pearson view. Fiducial distributions of regular parametric functions also have the above frequentist property. Some advantages of the fiducial inference are exhibited in four applications of the fiducial distribution. Many examples are given, in which the fiducial distributions cannot be derived by the existing methods. | XU Xingzhong & LI Guoying Department of Mathematics, Beijing Institute of Technology, Beijing 100081, China Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100080, China | 2006 | Science China Mathematics2006，49，3： | 16 |
| 8 | Cervical cancer screening in developing countries at a crossroad:Emerging technologies and policy choices显示文摘Cervical cancer(CC) represents the fourth most common malignancy affecting women all over the world and is the second most common in developing areas. In these areas,the burden from disease remains important because of the difficulty in implementing cytology-based screening programmes. The main obstacles inherent to these countries are poverty and a lack of healthcare infrastructures and trained practitioners. With the availability of new technologies,researchers have attempted to find new strategies that are adapted to low- and middle-income countries(LMIC) to promote early diagnosis of cervical pathology. Current evidence suggests that human papillomavirus(HPV) testing is more effective than cytology for CC screening. Therefore,highly sensitive tests have now been developed for primary screening. Rapid molecular methods for detecting HPV DNA have only recently been commercially available. This constitutes a milestone in CC screening in low-resource settings because it may help overcome the great majority of obstacles inherent to previous screening programmes. Despite several advantages,HPV-based screening has a low positive predictive value for CC,so that HPVpositive women need to be triaged with further testing to determine optimal management. Visual inspection tests,cytology and novel biomarkers are some options. In this review,we provide an overview of current and emerging screening approaches for CC. In particular,we discuss the challenge of implementing an efficient cervical screening adapted to LMIC and the opportunity to introduce primary HPV-based screening with the availability of point-of-care(POC) HPV testing. The most adapted screening strategy to LMIC is still a work in progress,but we have reasons to believe that POC HPV testing makes part of the future strategies in association with a triage test that still needs to be defined. | Rosa Catarino Patrick Petignat Gabriel Dongui Pierre Vassilakos | 2015 | World Journal of Clinical Oncology2015，6，6： | 16 |
| 9 | Era of universal testing of microsatellite instability in colorectal cancer显示文摘Colorectal cancer (CRC) incidence and mortality are constantly decreasing, but CRC still remains the third most prevalent cancer and the third most common cause of cancer death in both males and females in the United States. Recent rapid declines in CRC incidence rates have largely been attributed to increases in screening that can detect and remove precancerous polyps, and the decrease in death rates for CRC largely reflects improvements in early detection, treatment and the understanding of molecular/genetic basis of CRC. One of the important molecular/genetic findings is the presence of microsatellite instability (MSI) in CRCs. Many studies have shown the importance of MSI testing in diagnosing Lynch syndrome and predicting prognosis and response to chemotherapeutic agents in CRCs. Increased emphasis has been placed on the importance of MSI testing for all newly diagnosed individuals with CRCs. Both immunohistochemical staining (IHC) and polymerase chain reaction (PCR)-based MSI testing show high sensitivity and specificity in detecting MSI. The current clinical guidelines and histopathology features are indicative of, but not reliable in diagnosing Lynch syndrome and CRCs with MSI. Currently, there are evidences that universal testing for MSI starting with either IHC or PCR-based MSI testing is cost effective, sensitive, specific and is getting widely accepted. | Xuchen Zhang Jia Li | 2013 | World Journal of Gastrointestinal Oncology2013，5，2： | 16 |
| 10 | 肺栓塞患者D二聚体、纤维蛋白原测定的临床意义显示文摘目的探讨血浆D-二聚体和纤维蛋白原浓度的测定在肺栓塞的诊断与治疗中的价值。方法对39例经临床确诊为肺栓塞患者测定其血浆D-二聚体与纤维蛋白原浓度,并以其它呼吸道疾病患者为对照,对结果进行比较。结果肺栓塞患者血浆D-二聚体与纤维蛋白原浓度与对照组比较明显增高,差异有显著性(P<0.05)。经治疗后血浆D-二聚体与纤维蛋白原下降明显,差异有显著性(P<0.05)。结论血浆D-二聚体与纤维蛋白原测定可作为诊断肺栓塞的首选筛选试验,并对肺栓塞疗效判定有一定的临床意义。 | 徐丹 廖绍宗 倪琳婷 涂彩霞 蒋莉 | 2010 | 血栓与止血学2010，16，6： | 15 |
| 11 | Investigation on optimization design of equivalent water depth truncated mooring system显示文摘The oil industry is now increasingly concentrating their efforts and activities in connection with de- veloping fields in deeper waters, ranging typically from 500 m to 3000 m worldwide. However, the modeling of a full-depth system has become difficult presently; no tank facility is sufficiently large to perform the testing of a complete FPS with compliant mooring in 1000 m to 3000 m depth, within rea- sonable limits of model scale. Until recently, the most feasible procedure to meet this challenge seems to be the so-called 'hybrid model testing technique'. To implement this technique, the first and im- portant step is to design the equivalent water depth truncated mooring system. In this work, the opti- mization design of the equivalent water depth truncated mooring system in hybrid model testing for deep sea platforms is investigated. During the research, the similarity of static characteristics between the truncated and full depth system is mainly considered. The optimization mathematical model for the equivalent water depth truncated system design is set up by using the similarity in numerical value of the static characteristics between the truncated system and the full depth one as the objective function. The dynamic characteristic difference between the truncated and full depth mooring system can be minished by selecting proper design rule. To calculate the static characteristics of the mooring system, the fourth order Runge-Kutta method is used to solve the static equilibrium equation of the single mooring line. After the static characteristic of the single mooring line is calculated, the static charac- teristic of the whole mooring system is calculated with Lagrange numerical interpolation method. The mooring line material database is established and the standard material name and the diameter of the mooring line are selected as the primary key. The improved simulated annealing algorithm for continual & discrete variables and the improved complex algorithm for discrete variables are employed to per- form the optimization calculation. The C++ programming language is used to develop the computer program according to the object-oriented programming idea. To perform the optimization calculation with the two algorithms mentioned above respectively and the better result is selected as the final one. To examine the developed program, an example of equivalent water depth truncated mooring system optimum design calculation on a 100,000-t, turret mooring FPSO in water depth of 320 m are performed to obtain the conformation parameters of the truncated mooring system, in which the truncated water depth is 160 m. The model test under some typical environment conditions are performed for both the truncated and the full depth system with model scale factor λ=80. After comparing the corresponding results from the test of the truncated system with those from the full depth system test, it’s found that the truncated mooring system design in this work is successful. | ZHANG HuoMing SUN ZhiLin YANG JianMin GAO MingZheng | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，2： | 14 |
| 12 | 测土配方施肥在晚稻上的应用效果初探显示文摘不同配方施肥在晚稻上的比较试验结果表明:配方施肥比习惯施肥具有较好的增产增收效果,增产幅度在6%以上,增收幅度在680元/hm2以上。 | 方克明 钟国民 占木水 龚文亮 万静 | 2010 | 江西农业学报2010，22，8： | 14 |
| 13 | Occult hepatitis B virus infection and blood transfusion显示文摘Transfusion-transmitted infections including hepatitis B virus(HBV) have been a major concern in transfusion medicine. Implementation of HBV nucleic acid testing(NAT) has revealed occult HBV infection(OBI) in blood donors. In the mid-1980 s, hepatitis B core antibody(HBc) testing was introduced to screen blood donors in HBV non-endemic countries to prevent transmission of non-A and non-B hepatitis. That test remains in use for preventing of potential transmission of HBV from hepatitis B surface antigen(HBs Ag)-negative blood donors, even though anti-hepatitis C virus testshave been introduced. Studies of anti-HBc-positive donors have revealed an HBV DNA positivity rate of 0%-15%. As of 2012, 30 countries have implemented HBV NAT. The prevalence of OBI in blood donors was estimated to be 8.55 per 1 million donations, according to a 2008 international survey. OBI is transmissible by blood transfusion. The clinical outcome of occult HBV transmission primarily depends on recipient immune status and the number of HBV DNA copies present in the blood products. The presence of donor anti-HBs reduces the risk of HBV infection by approximately five-fold. The risk of HBV transmission may be lower in endemic areas than in non-endemic areas, because most recipients have already been exposed to HBV. Blood safety for HBV, including OBI, has substantially improved, but the possibility for OBI transmission remains. | Dong Hee Seo Dong Hee Whang Eun Young Song Kyou Sup Han | 2015 | World Journal of Hepatology2015，7，3： | 13 |
| 14 | Dynamic behavior of new cutting subgrade structure of expensive soil under train loads coupling with service environment显示文摘Expansive soil is sensitive to dry and wet environment change. And the volume deformation and inflation pressure of expansive soil may induce to cause the deformation failure of roadbed or many other adverse effects. Aimed at a high-speed railway engineering practice in the newly built Yun-Gui high-speed railway expansive soil section in China, indoor vibration test on a full-scaled new cutting subgrade model is carried out. Based on the established track-subgrade-foundation of expansive soil system dynamic model test platform, dynamic behavior of new cutting subgrade structure under train loads coupling with extreme service environment(dry, raining, and groundwater level rising) is analyzed comparatively. The results show that the subgrade dynamic response is significantly influenced by service conditions and the dynamic response of subgrade gradually becomes stable with the increasing vibration times under various service environment conditions. The vertical dynamic soil stress is related with the depth in an approximate exponential function, and the curves of vertical dynamic soil stress present a 'Z' shape distribution along transverse distance. The peak value of dynamic soil stress appears below the rail, and it increases more obviously near the roadbed surface. However, the peak value of dynamic soil stress is little affected outside 5.0 m of center line. The vibration velocity and acceleration are in a quadratic curve with an increase in depth, and the raining and groundwater level rising increase both the vibration velocity and the acceleration. The vertical deformations at different depths are differently affected by service environment in roadbed. The deformation of roadbed increases sharply when the water gets in the foundation of expansive soil, and more than 60% of the total deformation of roadbed occurs in expansive soil foundation. The laid waterproofing and drainage structure layer, which weakens the dynamic stress and improves the track regularity, presents a positive effect on the control deformation of roadbed surface. An improved empirical formula is then proposed to predict the dynamic stress of ballasted tracks subgrade of expansive soil. | 邱明明 杨果林 申权 杨啸 王刚 林宇亮 | 2017 | Journal of Central South University2017，24，4： | 13 |
| 15 | An Investigation and Suggestions for the Improvement of Brain Death Determination in China显示文摘Background: Brain death is the irreversible cessation of the function of the brain including the brainstem. In 2013, the Brain Injury Evaluation Quality Control Centre (BQCC) of the National Health and Family Planning Commission issued criteria and practical guidelines for the determination of brain death. This study aimed to evaluate whether the institutions have adopted these guidelines and to make suggestions for the improvement of the current criteria and practical guidelines for brain death determination in China. Methods: Consecutive brain death cases from 44 hospitals were evaluated for summary statistics for the following data: the performance of BQCC criteria and practical guidelines, clinical examination, apnea testing, ancillary testing, and the number of examinations as well as the waiting periods between examinations and details of who determined brain death. Data analysis was conducted from January 2013 to December 2017. Results: A total of 550 cases were obtained. All patients were determined to have deep coma and met the prerequisites for clinical testing. The performance rates of four brainstem reflex examinations (except cough reflex) ranged from 97.5% to 98.0%, and the completion rate as well as the coincidence rate were both 100.0%. The 238 cases (50.7%) completed apnea testing, and 231 cases (42.0%) had to stop apnea testing during the examination because of instability. The performance rates of the three ancillary tests, including electroencephalogram, short-latency somatosensory evoked potential, and transcranial Doppler, were 89.5%, 67.5%, and 79.5%, respectively;furthermore, the coincidence rates were 98.6%, 96.5%, and 99.5%, respectively. The combination of two ancillary tests was more accurate than one single ancillary test. A total of 401 (72.9%) cases successfully underwent two separate examinations to determine brain death with at least a 12-h waiting period. All brain death cases were determined by at least two qualified physicians. Conclusion: This study might provide suggestions for brain death determination in China. | Ying-Ying Su Wei-Bi Chen Gang Liu Lin-Lin Fan Yan Zhang Hong Ye Dai-Quan Gao Yi-Fei Liu Meng-Di jiang | 2018 | Chinese Medical Journal2018，，24： | 11 |
| 16 | Reviews of gas hydrate inhibitors in gas-dominant pipelines and application of kinetic hydrate inhibitors in China显示文摘During the development and application of natural gas,hydrate plugging the pipelines is a very important issue to solve.Currently,adding thermodynamic hydrate inhibitors(THIs)and kinetic hydrate inhibitors(KHIs)in gas-dominated pipelines is a main way to prevent hydrate plugging of flow lines.This paper mainly reviews the efforts to develop THIs and KHIs in the past 20 years,compare the role of various THIs,such as methanol,ethylene glycol and electrolyte,and give the tips in using.The direction of KHIs is toward high efficiency,low toxicity,low pollution and low cost.More than a hundred inhibitors,including polymers,natural products and ionic liquids,have been synthesized in the past decade.Some of them have better performance than the current commercial KHIs.However,there are still few problems,such as the complex synthesis process,high cost and low solubility,impeding the commercialization of these inhibitors.The review also summarized some application of KHIs in China.Research of KHIs in China began late.There are no KHIs used in gas pipelines.Only a few field tests have been carried out.In the end of this paper,the field test of self-developed KHIs by China is summarized,and the guidance is given according to the application results. | Yanhong Wang Shuanshi Fan Xuemei Lang | 2019 | Chinese Journal of Chemical Engineering2019，27，9： | 11 |
| 17 | GJB2 mutation spectrum in deaf population in a typical southeastern area of China显示文摘Mutations in GJB2 gene are the most frequently found mutations in patients with nonsyndromic hearing impairment. However, the spectrum and prevalence of mutations in this gene vary among different ethnic groups. In China, 30,000 infants are born with congenital hearing impairment annually. In order to provide appropriate genetic testing and counseling to the families, we investigated the molecular etiology of nonsyndromic deafness in 103 unrelated school children attending Nantong School for the Deaf and Mute in Jiangsu Province, China. The coding exon of the GJB2 gene was PCR amplified and sequenced. Sixty two GJB2 mutant alleles were identified in 35.9% (37/103) of the patients. Twenty five patients carried two pathogenic mutations and 12 patients carried one mutant allele. The 235delC was the most common mutation accounting for 69.4% (43/62) of GJB2 mutant alleles. The GJB2 mutant alleles accounted for 30.1% (62/206) of all chromosomes responsible for nonsyndromic hearing impairment. Testing of the 3 most prevalent deleterious frame shift mutations in this cohort detected 100% of all GJB2 mutant alleles. These results demonstrate that an effective genetic testing of GJB2 gene for patients and families with nonsyndromic hearing impairment is possible. | DAI Pu1*, YOU Yi-wen2*, CUI Jing-hong2*, YU Fei1, HAN Bing 1, KANG Dong-yang1, YUAN Hui-jun1, HAN Dong-yi1, 1. Department of Otolaryngology, PLA General Hospital, Beijing, People’s Republic China, 100853 2. Department of Otolaryngology, Nantong University Affiliated Hospital, Nantong, Jiangsu Province, People’s Republic China, 226001 *Pu Dai, Yiwen You, Jinghong Cui contribute equally to this paper | 2006 | Journal of Otology2006，1，2： | 10 |
| 18 | 球面型管路连接件密封性能分析及力学性能测试显示文摘针对火箭发动机推进系统管路中广泛使用的球面密封结构,选取四节点四边形板单元PLANE182作为基准单元对管路连接件进行有限元计算,得出管路连接件的应力场、应变场以及位移场的函数表达式,分析了其密封机理,讨论了弹塑性变形对金属密封的重要作用。在此基础上,采用非线性有限元法对接触单元进行了弹塑性分析和接触分析,并对管路连接件进行了耦合接触分析,在ANSYS平台上对耦合接触体进行了力学性能测试,详细分析了管路连接件的位移、应变和应力分布状况。 | 王建武 刘军生 陈少斌 | 2010 | 火箭推进2010，36，6： | 10 |
| 19 | Is tailored therapy based on antibiotic susceptibility effective?A multicenter,open-label,randomized trial显示文摘An effective eradication therapy of Helicobacter pylori(H.pylori)should be used for the first time.In this study,we assessed whether tailored therapy based on antibiotic susceptibility testing is more effective than traditional therapy.We also evaluated the factors that cause treatment failure in high-resistance areas.For this multicenter trial,we recruited 467 H.pylori-positive patients.The patients were randomly assigned to receive tailored triple therapy(TATT),tailored bismuth-containing quadruple therapy(TABQT),or traditional bismuthcontaining quadruple therapy(TRBQT).For the TATT and TABQT groups,antibiotic selection proceeded via susceptibility testing using an agar-dilution test.The patients in the TRBQT group were given amoxicillin,clarithromycin,esomeprazole,and bismuth.Successful eradication was defined as a negative 13C-urea breath test at least eight weeks after the treatment ended.Susceptibility testing was conducted using an agar-dilution test.The eradication rate was examined via intention-to-treat(ITT)and per-protocol(PP)analyses.The clarithromycin,levofloxacin,and metronidazole resistance rates were 26.12%,28.69%,and 96.79%,respectively.Resistance against amoxicillin and furazolidone was rare.The eradication rates for TATT,TRBQT,and TABQT were 67.32%,63.69%,and 85.99%in the ITT analysis(P<0.001)and 74.64%,68.49%,and 91.22%in the PP analysis(P<0.001),respectively.The efficacy of TABQTwas affected by clarithromycin resistance,and bismuth exerted a direct influence on TATT failure.TABQT was the most efficacious regimen for use in high-resistance regions,especially among clarithromycin-susceptible patients. | Jie Pan Zhengchao Shi Dingsai Lin Ningmin Yang Fei Meng Lang Lin Zhencheng Jin Qingjie Zhou Jiansheng Wu Jianzhong Zhang Youming Li | 2020 | Frontiers of Medicine2020，14，1： | 10 |
| 20 | 墩身混凝土侧压力理论计算与现场测试结果分析显示文摘通过对某桥185号墩身混凝土侧压力的现场测试,发现实测混凝土最大侧压力约为按照公路规范理论计算值的2.8倍。在分析国内、外有关混凝土侧压力计算公式后,建议高墩采用泵送高性能混凝土一次灌注到顶时,为防止出现墩身'爆模'事故,墩身混凝土侧压力标准值取值中应偏于安全地将混凝土初凝时间内的灌注高度按静水压力公式进行计算;模板设计时应考虑截面几何形状的影响。并且,在施工过程中,除加强对墩身拉杆、螺栓连接和焊缝进行检查外,还应将混凝土的初凝时间、灌注速度、坍落度等严格控制在计算限定的范围内。对于高性能混凝土侧压力计算公式,应进行更多的试验和研究。 | 李陆平 王吉连 田湖南 | 2010 | 世界桥梁2010，38，4： | 10 |
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