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    题名 作者 年代 出处 被引量
1Phase stability in high entropy alloys:Formation of solid-solution phase or amorphous phaseSheng GUO C.T. LIU 2011Progress in Natural Science:Materials International2011,21,6:91
2分散固相萃取-高效液相色谱法快速检测猕猴桃中的氯吡脲显示文摘建立了高效液相色谱快速检测猕猴桃中氯吡脲残留的方法。试样经乙腈提取、丙基乙二胺(PSA)分散固相萃取(DSPE)净化后在C18柱上以乙腈-0.01mol/L磷酸水溶液(体积比为35:65)为流动相进行分离,在260nm波长下检测。氯吡脲的检出限为0.005mg/kg,在0.05~10.00mg/L时线性关系良好(r=1.000)。试样在0.05,0.60,1.20mg/kg三个添加水平的回收率为82.0%~112.0%,相对标准偏差(RSD)(n=5)为2.41%。该方法简便快速,准确灵敏,适合大批量样品的快速处理。胡江涛 盛毅 方智 金晶 何开蓉 2007色谱2007,25,3:48
3Anatomical and chemical characteristics associated with lodging resistance in wheat显示文摘Anatomical and chemical characteristics of stems affect lodging in wheat(Triticum aestivum L.) cultivars. Traits associated with lodging resistance, such as plant height, stem strength, culm wall thickness, pith diameter, and stem diameter, were extensively investigated in earlier studies. However, the solid stem trait was rarely considered. In this study, we measured a range of anatomical and chemical characteristics on solid and hollow stemmed wheat cultivars. Significant correlations were detected between resistance to lodging and several anatomical features, including width of mechanical tissue, weight of low internodes, and width of stem walls. Morphological features that gave the best indication of improved lodging resistance were increased stem width, width of mechanical tissue layer, and stem density. Multiple linear regression analysis showed that 99% of the variation in lodging resistance could be explained by the width of the mechanical tissue layer, suggesting that solid stemmed wheat has several anatomical features for increasing resistance to lodging. In addition, microsatellite markers GWM247 and GWM340 were linked to a single solid stem QTL on chromosome 3BL in a population derived from the cross Xinongshixin(solid stem)/Line 3159(hollow stem). These markers should be valuable in breeding wheat for solid stem.Eryan Kong Dongcheng Liu Xiaoli Guo Wenlong Yang Jiazhu Sun Xin Li Kehui Zhan Dangqun Cui Jinxing Lin Aimin Zhang 2013The Crop Journal2013,1,1:43
4运用三维绘图软件SolidWorks改革工程图学教学的实践显示文摘指出了二维绘图软件AutoCAD已经不能满足目前企业新产品设计的需要以及现有的多媒体CAI课件仍然不能充分发挥教师的主导作用,不能满足交互性和实时性的教学需求。论述了工程图学引入三维CAD软件的必要性和重要性。运用三维机械软件SolidWorks,提出了三维画法几何,并从三维入手改革了工程图学的教学,连续3年在15个班的学生中进行了试点,取得了良好的教学效果。总结了改革过程中的一些做法和经验。江洪 吉维峰 2004工程图学学报2004,25,1:43
5Expression of vascular endothelial growth factor and its role in oncogenesis of human gastric carcinoma显示文摘AIM To establish the role of vascular endothelial growth factor (VEGF) in the oncogenesisof human gastric carcinoma more directly.METHODS The expression of VEGF and its receptor kinase-domain insert containing receptor (KDR) in human gastric cancer tissue were observed by immunohistochemical staining. VEGF levels were manipulated in human gastric cancer cell using eukaryotic expression constructs designed to express the complete VEGF165 complimentary DNA in either the sense or antisense orientation. The biological changes of the cells were observed in which VEGF was up-regulated or downregulated.RESULTS VEGF-positive rate was 50%, and VEGF was mainly localized in the cytoplasm and membrane of the tumor cells, while KDR was mainly located in the membrane of vascular endothelial cells in gastric cancer tissues and peri-cancerous tissue. In 2 cases of 50 specimens, the gastric cancer cells expressed KDR,localized in both the cytoplasm and membrane.Introduction of VEGF165 antisense into human gastric cancer cells ( SGC-7901, immunofluorescence intensity,31.6%)) resulted in a significant reduction in VEGFspecific messenger RNA and total and cell surface VEGF protein ( immunofluorescence intensity, 8.9%)(P<0.05). Conversely, stable integration of VEGF165 in the sense orientation resulted in an increase in cellular and cell surface VEGF (immunofluorescence intensity,75.4%) (P<0.05). Lowered VEGF levels were associated with a marked decrease in the growth of nude mouse xenografted tumor (at 33 days postimplantation, tomor volume: 345.40 ± 136.31 mm3) (P<0.05 vs control SGC7901 group: 1534.40 ± 362.88 mm3), whereas up-regulation of VEGF resulted in increased xenografted tumor size (at 33 days postimplantation, tomor volume: 2350.50 ± 637.70mm3) (P<0.05 vs control SGC-7901 group).CONCLUSION This study provides direct evidence that VEGF plays an important role in the oncogenesis of human gastric cancer.Du-Hu Liu Xue-Yong Zhang Dai-Ming Fan Yu-Xin Huang Jin-Shan Zhang Wei-Quan Huang Yuan-Qiang Zhang Qing-Sheng Huang Wen-Yu Ma Yu-Bo Chai Ming Jin Institute of Digestive Disease,Xijing Hospital,~2 Department of Gastroenterology,Tangdu Hospital,~3Department of Histology and Embryology,~4 Department of Microbiology,~5 Department of Biochemistry,Fourth Military Medical University,Xi’an 710033,Shaanxi Province,China 2001World Journal of Gastroenterology2001,7,4:37
6顶空固相微萃取气质联用检测鸭肉挥发性风味成分显示文摘采用顶空固相微萃取气质联用(Headspacesolidphasemicroextractioncombinedwithgaschromatgraphymassspectrometry,HS-SPME-GC-MS)分析检测了生鸭肉、烘烤鸭肉、水煮鸭脯肉和鸭腿肉的挥发性香气成分。共检测到55种风味化合物,其中烃类10种、酮类8种、醇类8种、醛类12种、酸类5种、酯类2种、含硫含氮及杂环化合物10种。刘源 周光宏 徐幸莲 刘扬岷 王利平 袁身淑 2005江苏农业学报2005,21,2:39
7固相萃取-气相色谱-质谱法同时测定水中9种药品及个人护理用品显示文摘采用固相萃取-气相色谱-质谱联用技术,建立了水体中9种药品及个人护理用品(水杨酸、萘普生、布洛芬、对乙酰氨基酚、降固醇酸、三氯生、双氯酚酸、酮洛芬和双酚 A)的定量分析方法。水样品经稀盐酸调节至 pH =3后,采用 Oasis HLB 固相萃取小柱进行富集净化;选用三甲基氢氧化硫( TMSH)为衍生化试剂,在常温条件下对目标物进行快速甲基化;以气相色谱-质谱法选择离子监测模式(GC-MS-SIM)进行检测,由2,4,5-涕丙酸为内标进行定量分析。本实验分别对固相萃取和衍生化等前处理条件进行了系统的研究。在优化的实验条件下,方法的回收率为50.7~115.4%,相对标准偏差均不高于10%,检出限为0.03~0.30μg / L,定量限为0.15~1.50μg / L。利用该方法对东莞市某农田灌溉水进行了分析,4种目标物在样品中有检出,最大质量浓度范围为0.176~0.998μg / L。结果表明该方法操作简便,灵敏可靠。贾妍艳 谭建华 徐晨 汤嘉骏 王赢利 解启来 2014色谱2014,32,3:25
8固相萃取-超高效液相色谱-电喷雾串联质谱法同时测定地表水中16种全氟有机化合物显示文摘建立了固相萃取-超高效液相色谱-电喷雾串联三重四极杆质谱联用技术分析水中16种全氟有机化合物的高通量检测方法。样品经 WAX 固相萃取柱富集和净化后,采用 Waters ACQUITY UPLCTM BEH C18色谱柱,含2 mmol/L乙酸铵的甲醇和含2 mmol/L乙酸铵的水作为流动相进行梯度洗脱,质谱采用电喷雾负离子电离,多反应监测模式检测。16种全氟有机化合物在0.5~100μg/L或1.0~100μg/L 浓度范围内线性关系良好,相关系数为0.9987~0.9999,方法的检出限为0.06~0.46 ng/L;高、中、低3个添加水平的回收率为67.6%~103%,相对标准偏差为2.94%~12.0%。结果表明,该方法灵敏、准确且检测范围广,分析速度快,是一种适于实际水样中全氟有机化合物检测分析的方法。张明 唐访良 俞雅雲 陈峰 徐建芬 叶永根 2014色谱2014,32,5:22
9液相色谱-串联质谱同时测定禽肉组织中盐酸金刚烷胺、盐酸金刚乙胺、地塞米松、替米考星及喹乙醇代谢物的残留量显示文摘建立了同时测定禽肉组织中盐酸金刚烷胺、盐酸金刚乙胺、地塞米松、替米考星及喹乙醇代谢物残留量的液相色谱-串联质谱分析方法.样品用2 mol/L氢氧化钠溶液水解,盐酸调节pH值后,以乙腈作为提取溶剂,经C18固相萃取柱净化.各待测物分别经0.1%甲酸甲醇溶液和氨化甲醇(0.1%氨水)洗脱,Phe-nomenex Kinetex C1s(100 mm×4.6 mm,2.6 μm)色谱柱进行分离,采用0.1%甲酸(含5 mmol/L乙酸铵)-甲醇作流动相,梯度洗脱,串联质谱法对5种药物含量进行测定.结果表明,5种药物在2 ~ 100 μg/L范围内线性关系良好,相关系数为0.996 2 ~0.999 8.在加标浓度为5~50 μg/kg的禽肉组织中,这5种药物的加标回收率为73.7% ~92.3%,相对标准偏差(n=5)为3.9% ~ 16.6%,检出限为0.2~ 3.0 μg,/kg,定量下限为0.7~ 10 μg/kg.方法快速、简便、经济实用,符合法规要求,可满足日常检测的需要.易锡斌 裘立群 刘世琦 黄晓琴 2015分析测试学报2015,34,3:22
10Lithium–matrix composite anode protected by a solid electrolyte layer for stable lithium metal batteries显示文摘Lithium (Li) metal with an ultrahigh specific theoretical capacity and the lowest reduction potential is strongly considered as a promising anode for high-energy-density batteries. However, uncontrolled lithium dendrites and infinite volume change during repeated plating/stripping cycles hinder its practical applications immensely. Herein, a house-like Li anode (housed Li) was designed to circumvent the above issues. The house matrix was composed of carbon fiber matrix and affords a stable structure to relieve the volume change. An artificial solid electrolyte layer was formed on composite Li metal, just like the roof of a house, which facilitates uniform Li ions diffusion and serves as a physical barrier against electrolyte corrosion. With the combination of solid electrolyte layer and matrix in the composite Li metal anode, both dendrite growth and volume expansion are remarkably inhibited. The housed Li|LiFePO4 batteries exhibited over 95% capacity retention after 500 cycles at 1.0 C in coin cell and 85% capacity retention after 80 cycles at 0.5 C in pouch cell. The rationally combination of solid electrolyte layer protection and housed framework in one Li metal anode sheds fresh insights on the design principle of a safe and long-lifespan Li metal anode for Li metal batteries.Xin Shen Xinbing Cheng Peng Shi Jiaqi Huang Xueqiang Zhang Chong Yan Tao Li Qiang Zhang 2019Journal of Energy Chemistry2019,28,10:23
11转录组的测序方法及应用研究概述显示文摘转录组研究是基因的结构和功能研究的基础,转录组测序技术在近年来取得了很大的进展,被应用到多种动植物中。利用其能够获得大量未知序列的优势,已经被广泛应用到未知基因挖掘、分子调控及相关代谢途径中。该研究主要介绍了转录组研究的方法、转录组测序技术的发展及其在动植物中的重要应用,并讨论其存在的问题及发展趋势。姚娜 刘秀明 董园园 王南 孟璐璐 李海燕 2017北方园艺2017,,12:20
12机械行业三维建模技术综述显示文摘针对机械行业广泛使用的三维建模技术进行了系统的调研分析,以常用软件为分析单元,从其功能特点、发展历程、技术更新趋势、应用领域等方面着手,进行了详细的阐述;同时阐述了三维建模技术之间以及三维建模技术与常用分析软件之间及办公软件的接口技术。希望能够引导初学者选择合适的建模技术进行学习;帮助那些要引进三维建模技术的企业合理地选择建模技术;拓宽已经掌握三维建模技术人员的眼界。罗阿妮 张桐鸣 刘贺平 李杨 2010机械制造2010,48,10:20
13基于Solid Works和ANSYS某舵机齿轮装配体模态分析显示文摘固有频率和振型是承受动态载荷结构设计中的重要参考指标,模态分析可以确定一个结构的固有频率和振型。基于Solid Works及其插件Gear Trax对齿轮装配体进行三维参数化设计,然后通过特殊接口导入ANSYS中,对其模态进行有限元求解。针对静态线性模态分析方法不能满足高速旋转和频繁变速工况的实际问题,通过求解两种临界状态的固有频率,从而确定该系统固有频率的范围,有效地解决了类似问题。徐春雨 陈刚 周渊键 2012机械传动2012,36,4:19
14用VisualC++开发SolidW orks的关键技术显示文摘简要介绍了用 Visual C+ +开发 Solid-Works的基本原理 ,并通过实例论述了开发陈岳坪 罗意平 王平安 2002机械与电子2002,20,2:19
15Smoothed particle hydrodynamics(SPH) for modeling fluid-structure interactions显示文摘Fluid-structure interaction(FSI) is a class of mechanics-related problems with mutual dependence between the fluid and structure parts and it is observable nearly everywhere, in natural phenomena to many engineering systems. The primary challenges in developing numerical models with conventional grid-based methods are the inherent nonlinearity and timedependent nature of FSI, together with possible large deformations and moving interfaces. Smoothed particle hydrodynamics(SPH) method is a truly Lagrangian and meshfree particle method that conveniently treats large deformations and naturally captures rapidly moving interfaces and free surfaces. Since its invention, the SPH method has been widely applied to study different problems in engineering and sciences, including FSI problems. This article presents a review of the recent developments in SPH based modeling techniques for solving FSI-related problems. The basic concepts of SPH along with conventional and higher order particle approximation schemes are first introduced. Then, the implementation of FSI in a pure SPH framework and the hybrid approaches of SPH with other grid-based or particle-based methods are discussed. The SPH models of FSI problems with rigid, elastic and flexible structures, with granular materials, and with extremely intensive loadings are demonstrated. Some discussions on several key techniques in SPH including the balance of accuracy, stability and efficiency, the treatment of material interface, the coupling of SPH with other methods, and the particle regularization and adaptive particle resolution are provided as concluding marks.Moubin Liu Zhilang Zhang 2019Science China(Physics,Mechanics & Astronomy)2019,62,8:19
16challenges of advanced hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC) is an aggressive malignancy,resulting as the third cause of death by cancer each year. The management of patients with HCC is complex,as both the tumour stage and any underlying liver disease must be considered conjointly. Although surveillance by imaging,clinical and biochemical parameters is routinely performed,a lot of patients suffering from cirrhosis have an advanced stage HCC at the first diagnosis. Advanced stage HCC includes heterogeneous groups of patients with different clinical condition and radiological features and sorafenib is the only approved treatment according to Barcelona Clinic Liver Cancer. Since the introduction of sorafenib in clinical practice,several phase Ⅲ clinical trials have failed to demonstrate any superiority over sorafenib in the frontline setting. Locoregional therapies have also been tested as first line treatment,but their role in advanced HCC is still matter of debate. No single agent or combination therapies have been shown to impact outcomes after sorafenib failure. Therefore this review will focus on the range of experimental therapeutics for patients with advanced HCC and highlights the successes and failures of these treatments as well as areas for future development. Specifics such as dose limiting toxicity and safety profile in patients with liver dysfunction related to the underlying chronic liver disease should be considered when developing therapies in HCC. Finally,robust validated and reproducible surrogate end-points as well as predictive biomarkers should be defined in future randomized trials.Stefano Colagrande Andrea L Inghilesi Sami Aburas Gian G Taliani Cosimo Nardi Fabio Marra 2016World Journal of Gastroenterology2016,22,34:19
17矿井通风网络三维仿真与优化系统研究显示文摘针对矿井通风系统优化软件存在的功能不够全面、通用性不好、数据输入繁琐、可视化差等问题,运用面向对象语言VB为开发工具S、QL Server为后台数据库,SolidWorks为图形平台,开发了一套矿井通用的通风系统仿真与优化软件,有效解决了矿井通风信息管理、三维矿井通风立体图的自动生成、矿井通风网络自动解算、风网参数的自动标注等问题。在多个金属矿山应用的结果验证了其可靠性,具有良好的实用价值和推广应用前景。沈澐 王海宁 2009矿业安全与环保2009,36,2:18
18MICROSTRUCTURE EVALUATION OF SEMI-SOLID STEEL MATERIALS IN ROLLING PROCESS AND THE RESULTING MECHANICAL PROPERTIES显示文摘The experimental study on the familiar 60Si2Mn and lCrl8Ni9Ti materials rolled in the semi-solid state was carried out. Experimental results show that the segregation of liquid occurs when the semi-solid slurry is rolled, which influences the microstructure and mechanics performance of workpiece under room temperature. The globular solid particles don’t present plastic deformation unless high solid fraction. At the same time, the mechanics property of workpiece is pretty good while the semi-solid slurry of 1Cr18Ni9Ti material is rolled by a pass and no other treatment.R.B. Song, Y.L. Kang, J.L. Sun, A.M. Zhao and W.M. Mao School of Materials Science & Engineering, University of Science & Technology Beijing, Beijing 100083,China 2001Acta Metallurgica Sinica(English Letters)2001,14,5:17
19Dehydration melting of solid amphibolite at 2.0 GPa: Effects of time and temperature显示文摘Two sets of dehydration-melting with a natural solid amphibolite, collected from North Himalayan structure zone, Tibet, have been carried out in multi-anvil apparatus at 2.0 GPa and 800―1000℃, for 12―200 h. One is keeping the pressure at 2.0 GPa and the annealing time of 12 h, changing the temperature (800―1000℃). The other is keeping the pressure at 2.0 GPa and temperature at 850℃, varying the annealing time (12―200 h). The products are inspected with microscope and electron probe. The results indicate that at 2.0 GPa, annealing time of 12 h, garnets, melts and clinopyroxenes occur in amphibolite gradually with increasing temperature and the chemical compositions of melt vary from tonalite to granodiorite, and then to tonalite. However, at 2.0 GPa and 850℃, with the annealing time increasing, the garnets, melts and cli-nopyroxenes also occur in amphibolite gradually and the chemical compositions of melt vary from tonalite to granodiorite. In both cases, melts interconnect with each other when the contents of melt are over the 5 vol.%. the viscosities of the melt produced in amphibolite at temperature higher than 850℃ are on a level with 104 Pa·s. The interconnected melt with such a viscosity may segregate from the source rock and form the magma over reasonable geological time. Therefore, it is believed that at the lower part of the overthickened crust, the tonlitic and grano-dioritic magma may be generated through the dehydration melting of amphibolite.ZHOU Wenge1, XIE Hongsen1, LIU Yonggang1, ZHENG Xiaogang1, ZHAO Zhidan2 & ZHOU Hui3 1. Laboratory of Material in the Earth’s Interior, Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550002, China 2. Department of Geology, China University of Geosciences, Beijing 100083, China 3. Department of Geology, Peking University, Beijing 100871, China 2005Science China Earth Sciences2005,48,8:17
20烧结温度对Ti/IrO_2-Ta_2O_5纳米氧化物阳极微观结构和电催化性能的影响(英文)显示文摘采用Pechini法制备Ti/IrO2-Ta2O5纳米氧化物阳极,通过SEM、EDX、XRD、极化曲线、循环伏安、电化学阻抗谱及强化电解寿命试验等测试手段,研究了烧结温度对Ti/IrO2-Ta2O5阳极微观结构和电催化性能的影响。结果表明,阳极涂层成分分布均匀,IrO2晶粒偏析不明显;Ta在铱钽固溶体中的固溶度随烧结温度升高而增大,涂层晶粒逐渐细化。随着烧结温度的升高,阳极析氧电催化活性降低,电化学活性表面积减小;500℃下所得Ti/IrO2-Ta2O5阳极表现出最高的强化电解寿命。辛永磊 许立坤 王均涛 李相波 2010稀有金属材料与工程2010,39,11:16
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