Segmental duodenectomy for gastrointestinal stromal tumor of the duodenum

查看全文 作　　者：Nicolas Christian [1]Buchs;Pascal [1]Bucher;Pascal [1]Gervaz;Sandrine [1]Ostermann;Franois [1]Pugin;Philippe [1]Morel 机构地区：[1]Department of Surgery, University Hospital Geneva 出　　处：《World Journal of Gastroenterology》索引2010年第16卷第22期,共5页 摘　　要：AIM: To evaluate the results of segmental duodenectomy (SD) and pancreaticoduodenectomy (PD) for duodenal gastrointestinal stromal tumor (GIST) and help clinicians with surgical management. METHODS: All patients who underwent surgery for non-metastatic GIST of the duodenum in a single institution since 2000 were prospectively followed up. Seven patients (median age 51 years, range: 41-73 years) were enrolled: five underwent SD and two underwent PD. RESULTS: All the patients had a complete resection (R0), with no postoperative morbidity and mortality. Among the SD group, GIST was classified as low risk in two patients, intermediate risk in two, and high risk in one, according to the Fletcher scale, (vs two high risk patients in the PD group). With a median followup of 41 (18-85) mo, disease-free survival (DFS) rateswere 100% after SD and 0% after PD (P < 0.05). The median DFS was 13 mo in the PD group. CONCLUSION: Whenever associated with clear surgical margins, SD is a reliable and curative option for most duodenal GISTs, and is compatible with longterm DFS. 关 键 词：Gastrointestinal stromal tumor Duodenal neoplasms Segmental duodenectomy PANCREATICODUODENECTOMY