Outcome in obscure gastrointestinal bleeding after capsule endoscopy

查看全文 作　　者：Alex Caas-[1]Ventura;Lucia [1]Márque;Xavier [1]Bessa;Josep Maria DedeuDepartment of Gastroenterology;Hospital del Mar Research Institute;Pompeu Fabra University;Marc [1]Puigvehí;Sílvia Delgado-[1]Aros;Ines Ana Ibá[1]ez;Agustin [1]Seoane;Luis [1]Barranco;Felipe [1]Bory;Montserrat [1]Andreu;Begoa González-[2]Suárez

机构地区：[1]Department of Gastroenterology,Hospital del Mar Research Institute,Pompeu Fabra University;[2]Endoscopic Unit,Gastroenterology Department,ICMDiM. Hospital Clínic

出　　处：《World Journal of Gastrointestinal Endoscopy》索引2013年第5卷第11期,共8页

摘　　要：AIM: To investigate the clinical impact of capsule endoscopy(CE) after an obscure gastrointestinal bleeding(OGIB) episode, focusing on diagnostic work-up, followup and predictive factors of rebleeding. METHODS: Patients who were referred to Hospital del Mar(Barcelona, Spain) between 2007 and 2009 for OGIB who underwent a CE were retrospectively analyzed. Demographic data, current treatment with non-steroid antiinflammtory drugs or anticoagulant drugs, hemoglobin levels, transfusion requirements, previous diagnostic tests for the bleeding episode, as well as CE findings(significant or non-significant), work-up and patient out-comes were analyzed from electronic charts. Variables were compared by χ 2 analysis and Student t test. Risk factors of rebleeding were assessed by Log-rank test, Kaplan-Meier curves and Cox regression model. RESULTS: There were 105 patients [45.7% women, median age of 72 years old(interquartile range 56-79)] and a median follow-up of 326 d(interquartile range 123-641) included in this study. The overall diagnostic yield of CE was 58.1%(55.2% and 63.2%, for patients with occult OGIB and overt OGIB, respectively). In 73 patients(69.5%), OGIB was resolved. Multivariate analysis showed that hemoglobin levels lower than 8 g/dL at diagnosis [hazard ratios(HR) = 2.7, 95%CI: 1.9-6.3], patients aged 70 years and above(HR = 2.1, 95%CI: 1.2-6.1) and significant findings in CE(HR = 2.4, 95%CI: 1.1-5.8) were independent predictors of rebleeding. CONCLUSION: One third of the patients presented with rebleeding after CE; risk factors were hemoglobin levels < 8 g/dL, age ≥ 70 years or the presence of significant lesions. 关键词：CAPSULE endoscopy Obscure gastrointestinal BLEEDING Small BOWEL ANGIODYSPLASIA ENTEROSCOPY

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Outcome in obscure gastrointestinal bleeding after capsule endoscopy

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