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Laparoscopic total colectomy: Does the indication influence the outcome?

查看全文 作  者:Eddy [1,2]Cotte;Faheez [3]Mohamed;Stéphane [4]Nancey;Yves Fran[1,2]ois;Olivier [1,2]Glehen;Bernard [4]Flourié;Jean-Christophe [5]Saurin;Gilles [5]Poncet 高影响力作者 机构地区:[1]Department of Digestive Surgery, Centre Hospitalo-Universitaire Lyon Sud, Hospices Civils de Lyon;[2]EA 3738, Université Claude Bernard Lyon1, Faculté de Médecine Lyon Sud;[3]Colorectal Research Unit, Basingstoke and North Hampshire Foundation Trust;[4]Department of Gastro-enterology, Centre Hospitalo-Universitaire Lyon-Sud, Hospices Civils de Lyon;[5]Digestive Federation, Centre Hospitalo-Universitaire Edouard Herriot, Hospices Civils de Lyon高影响力机构 出  处:《World Journal of Gastrointestinal Surgery》索引2011年第3卷第11期,共6页高影响力期刊 摘  要:AIM: To assess and compare outcomes of laparoscopic total colectomy performed for a variety of indications. METHODS: Sixty six patients underwent laparoscopic total colectomy for inflammatory bowel disease (IBD) (13) and other diseases (53). Data on demographics, pre and post-operative outcomes were collected prospectively.RESULTS: Mean operative time was 4.5 h. Conversion rate was 13.6%. Total colectomy performed for IBD was associated with a signifi cantly higher anastomotic leak rate (23.1% vs 1.9%, P < 0.05). On univariate analysis, hand sewn anastomosis and treatment with more than 20 mg of prednisolone for at least 3 mo was associated with a higher anastomotic leak rate (P < 0.05). No signifi cant difference was found in return of gut function and overall morbidity between disease groups. CONCLUSION: Laparoscopic total colectomy is feasible and outcomes are equivalent whatever the indica- tion, except for anastomotic leak rate which is higher for patients with IBD. 关 键 词:COLECTOMY Inflammatory bowel disease Laparoscopy FAMILIAL adenomatous POLYPOSIS CONSTIPATION Colonic neoplasms HEREDITARY nonpolyposis DIVERTICULOSIS Treatment outcomes
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