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Microstructural analysis of pineal volume using trueFISP imaging

查看全文 作  者:Jan M [1]Bumb;Marc A [2,3]Brockmann;Christoph [2]Groden;Ingo [2]Nolteb 高影响力作者 机构地区:[1]Department of Psychiatry and Psychotherapy,Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University;[2]Department of Neuroradiology, University Hospital Mannheim;[3]Department of Diagnostic and Interventional Neuroradiology, University Hospital of the RWTH Aachen高影响力机构 出  处:《World Journal of Radiology》索引2013年第5卷第4期,共7页高影响力期刊 摘  要:AIM:To determine the spectrum of pineal microstructures (solid/cystic parts) in a large clinical population using a high-resolution 3D-T2-weighted sequence. METHODS:A total of 347 patients enrolled for cranial magnetic resonance imaging were randomly included in this study. Written informed consent was obtained from all patients. The exclusion criteria were artifacts or mass lesions prohibiting evaluation of the pineal gland in any of the sequences. True-FISP-3D-imaging (1.5-T, isotropic voxel 0.9 mm) was performed in 347 adults (55.4 ± 18.1 years). Pineal gland volume (PGV), cystic volume, and parenchyma volume (cysts exclud- ed) were measured manually. RESULTS:Overall, 40.3% of pineal glands were cystic. The median PGV was 54.6 mm 3 (78.33 ± 89.0 mm 3 ), the median cystic volume was 5.4 mm 3 (15.8 ± 37.2mm 3 ), and the median parenchyma volume was 53.6 mm 3 (71.9 ± 66.7 mm 3 ). In cystic glands, the standard deviation of the PGV was substantially higher than in solid glands (98% vs 58% of the mean). PGV declined with age (r = -0.130, P = 0.016). CONCLUSION:The high interindividual volume variation is mainly related to cysts. Pineal parenchyma volume decreased slightly with age, whereas genderrelated effects appear to be negligible. 关 键 词:PINEAL GLAND VOLUME PINEAL CYST Magnetic resonance IMAGING Etiology Reference range
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