An overall assessment of circumanal gland adenoma in a terrier mix breed dog

查看全文 作　　者：Javad [1]Javanbakht;Abbas [1]Tavassoli;Farhang [1]Sasani;Atefeh [1]Sabbagh;Mehdi Aghamohamad [2]Hassan;Shohreh Alian [3]Samakkhah;Radmehr [4]Shafiee;Meysam [4]Jani;Samad [5]Alimohammadi;Reza [1]Samani;Fardin [2]Barati;Vahideh Rahmani [4]Ghalee 机构地区：[1]Department of Pathology, Faculty of Veterinary Medicine, Tehran University,Tehran, Iran;[2]Department of Clinical Science, Faculty of Veterinary Medicine, Tehran University,Tehran, Iran;[3]Department of Health Food Hygiene, Faculty of Veterinary Medicine, Tehran University,Tehran, Iran;[4]Graduate Faculty of Veterinary Medicine, Tehran University,Tehran, Iran;[5]Department of Physiology, Faculty of Veterinary Medicine, Tehran University,Tehran, Iran 出　　处：《Asian Pacific Journal of Tropical Biomedicine》索引2013年第3卷第7期,共4页 摘　　要：In September 2012,a 10-year-old,intact male,terrier mix breed dog was evaluated because ofmultiple,0.5 to 1.2 cm in diameter,round,intradermal nodules around the anus.It had surgery toexcise a firm,painful swelling in the left ventrolateral perianal region and the excision part wasobserved under light microscopy.The mass spreading in to sub acute was of left hind leg out fromthe ventro-lateral of anus,1.2 cm伊1 cm/0 cm伊0.5 cm in size and 125 g in weight.A completeblood cell count,serum biochemistry panel,and urinalysis(cystocentesis sample)were evaluated.Significant laboratory data demonstrated microcytic anemia(hemoglobin of 6.4 mg/dL)and normalcoagulation times.No remarkable abnormalities were found in the complete blood count and anionized calcium of 1.91 mmol/L(reference range,1.1-1.3 mmol/L)was confirmed hypercalcemia.On cytologic and histopathologic examinations,evaluation of the aspirate revealed a prominentpopulation of round-to-polygonal nucleated cells arranged as cohesive groups with isolatedindividual cells.A mild degree of anisocytosis and anisokaryosis was observed.In addition,smaller reserve type cells,with darker cytoplasm and a higher nucleocytoplasmic ratio.Theadenomas generally retain the lobular architecture,but some may contain focal areas of cellularpleomorphism.These changes may suggest malignant transformation and have led to discordantinterpretations,the well-developed stroma surrounding the lobules and hepatoid cells was noted.Ulceration,hemorrhage,necrosis and secondary infection with inflammatory cell infiltrates arecommon.These cytology and histopathology features are consistent with hepatoid gland adenoma. 关 键 词：Hepatoid GLAND ADENOMA CYTOLOGY HISTOPATHOLOGY DOG Blood cell count