Peripapillary retinal nerve fibre layer thickness measurement with SD-OCT in normal and glaucomatous eyes:distribution and correlation with age

查看全文 作　　者：George [1]Kampougeris;Dimitrios [1]Spyropoulos;Adrianna [1]Mitropoulou;Aggeliki [1]Zografou;Pericles [1]Kosmides

机构地区：[1]Department of Ophthalmology,Athens Medical Center

出　　处：《International Journal of Ophthalmology(English edition)》索引2013年第6卷第5期,共4页

摘　　要：AIM:To determine peripapillary retinal fiber layer thickness(RNFL) measured with spectral domain optical coherence tomography(SD-OCT) in normal and glaucomatous eyes in a large sample of exclusively white population and compare results with other similarly constructed studies. METHODS:Average,maximum,minimum and per quadrant RNFL thickness were measured in normal and glaucomatous Greek patients with a scanning laser ophthalmoscope(SLO)/SD-OCT device.The effect of age in normal RNFL thickness was also determined.RESULTS:A total of 278 normal(278 patients) and 67 glaucomatous(67 patients) eyes were included in the study.Average RNFL thickness was 114.8±13.3μm in normal and 92.1±18.5μm in glaucomatous eyes(P<0.001).In normal discs,superior quadrant was the thickest,followed by the inferior,nasal and temporal.Decline of normal RNFL thickness with age was statistically significant for average RNFL thickness(1.92μm per decade of life) and for the superior and inferior quadrants of the disc. CONCLUSION:SD-OCT peripapillary RNFL measurements can be used to distinguish between normal and glaucomatous eyes and establish normative databases,since normal disc measurements differ between different ethnic groups and between different SD-OCT devices. 关键词：SD-OCT RETINAL fiber layer thickness OPTIC DISC

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Peripapillary retinal nerve fibre layer thickness measurement with SD-OCT in normal and glaucomatous eyes:distribution and correlation with age

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