Residues important to the allosteric regulation on ligand binding affinity in β3 integrins

查看全文 作　　者：Jizhong Lou1,Wei Chen2,Mei-Yin Chou3,Cheng Zhu1,2,3,4(1Parker H.Petit Institute for Bioengineering and Bioscience,2Woodruff School of Mechanical Engineering,and 3School of Physics,4Coulter Department of Biomedical Engineering,,Georgia Institute of Technology,GA,USA) 出　　处：《医用生物力学》索引2009年第24卷第S1期,共1页 摘　　要：Integrins are heterodimers that mediate cell adhesion and transduce signals bidirectionally across the cell membrane.Integrins often exist in low affinity(or inactive) states for 关 键 词：Residues important to the allosteric regulation on ligand binding affinity in