A review study on medicinal plants used in the treatment of learning and memory impairments

查看全文 作　　者：Nahid [1]Jivad;Zahra [2]Rabiei

机构地区：[1]Neurology Department,Shahrekord University of Medical Science,Shahrekord,Iran;[2]Department of Physiology and Pharmacology,Shahrekord Unicersity of Medical Science,Shahrekord,Iran

出　　处：《Asian Pacific Journal of Tropical Biomedicine》索引2014年第4卷第10期,共10页

基　　金：Supported by Research and Technology Deputy of Shahrekord University of Medical Sciences 摘　　要：Alzheimer′s disease(AD) is a progressive brain disorder thai gradual!) impairs the person's memory and ability to learn,reasoning.judgment,communication and daily activities.All is characterized clinically by cognitive impairment and pathologically by the deposition of β amyloid plaques and neurofibrillary tangles,and the degeneration of the cholinergic basal forebrain.During the progression of AD patients may produce changes in personality and behavior,such as anxiety,paranoia,confusion,hallucinations and also to experience delusions and lanlasies.The first neurotransmitter defect discovered in Al) involved acetylcholine as cholinergic function is required for short—term memory.Oxidative stress may underlie the progressive neurodegeneration characteristic of AD.Brain structures supporting memory are uniquely sensitive to oxidative stress due to their elevated demand for oxygen.The neurodegenerative process in AD may involveβ amyloid toxicity.Neurotoxicity of β amyloid appears to involve oxidative stress.Currently,there is no cure for this disease but in new treatments,reveals a new horizon on the biology of this disease.This paper reviews the effects of a number of commonly used types of herbal medicines for the Irealment of AD.The objective of this article was to review evidences from controlled studies in order to determine whether herbs can be useful in the treatment of cognitive disorders in the elderly. 关键词：Alzheimer’s DISEASE MEDICINAL PLANTS OXIDATIVE stress CHOLINERGIC function

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A review study on medicinal plants used in the treatment of learning and memory impairments

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