Human immunodeficiency virus-related primary central nervous system lymphoma: factors influencing survival in 111 patients

查看全文 作　　者：Newell [1]ME;Hoy [1]JF;Cooper [1]SG;DeGraaff [1]B;Grulich [1]AE;Bryant [1]M;Millar [1]JL;Brew [1]BJ;Quinn [1]DI 机构地区：[1]National Centre in HIV Epidemiology and Clinical Research,University of New South Wales,Sydney,Australia. 出　　处：《中国神经肿瘤杂志》索引2004年第2卷第2期,共1页 摘　　要：BACKGROUND: The current study evaluated factors influencing survival in patients diagnosed with human immunodeficiency virus (HIV)-related primary central nervous system lymphoma (PCNSL), with a focus on the effects of therapeutic radiotherapy (RT) and highly active antiretroviral therapy (HAART). METHODS: A retrospective chart review of patients with a diagnosis of HIV-related PCNSL at one of five university hospitals between 1987 and 1998 was performed. Clinical details including antiretroviral agent use, brain imaging scan results, RT use, and survival outcomes were recorded. RESULTS: One hundred eleven patients with HIV-related PCNSL were identified. The annual incidence decreased significantly between 1992 and 1995 and between 1996 and 1998 (P=0.04). 关 键 词：原发性中枢神经系统淋巴瘤 生存 影响因素 人类免疫缺陷病毒