Successful immunological treatment of gallbladder cancer in India―Case report

查看全文 作　　者：KHAN Jamal [1]A.;YAQIN [1]Sharmin

机构地区：[1]Microbiology Research Lab C-38/Sector 20, Noida Zip 201301, India

出　　处：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》索引2006年第7卷第9期,共6页

基　　金：Project partly supported by grant from Amim Cancer Trust andPatient’s Co-Operation, India 摘　　要：Gallbladder cancer has a poor outcome because of its anatomy and location. Often, the diagnosis is made very late due to its silent course. Post-operated cases do respond to chemotherapy but the survival is counted in months and the quality of life is further hampered due to toxicity of drugs. Immunotherapy holds good promise in non-responding cancers treated by conventional chemotherapeutic agents. Among various therapies, dendritic cell therapy is growing at rapid pace due to its acceptable rationale. It has been utilized in treating successfully resected stage III (T2, N1, M0) gallbladder cancer in one of our patients. A 48 years old lady treated with this therapy is free of metastasis with ten doses of autologous dendritic cell vaccine constructed by utilizing resected tumor lysate antigen. She has received ten doses of therapy in 14 months of her treatment. This therapy has proven to be safe and without apparent side effects. The positive clinical response obtained supports that autologous dendritic cell-based immunotherapy is a promising therapeutic approach for refractory gallbladder cancers. 关键词：胆囊癌树突细胞免疫疗法印度

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Successful immunological treatment of gallbladder cancer in India―Case report

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