Synthesis of 2-Heterocyclomethyl-5-diphenylmethylene-cyclopentanone Hydrochlorides and their Inhibitory Effect on Tumor Cell Growth

查看全文 作　　者：Yun Hai ZHANG Lin Xiang ZHAO Zhen Jun BIAN Rui WANG Fu Yuan [1]SUN 机构地区：[1]School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016 出　　处：《Chinese Chemical Letters》索引2006年第17卷第9期,共4页 基　　金：supported by the National Natural Science Foundation of China(No.30171099) 摘　　要：Sixteen new 2-heterocyclomethyl-5-diphenylmethylenecyclopentanone hydrochlorides were designed and synthesized. The growth inhibitory effect of these compounds in vitro was conducted using a MTT assay in human breast cancer T47D cells. 关 键 词：环戊酮 合成 生长抑制 癌细胞 生物活性