维普中文期刊产品整合服务

The Antitumor Components from Marine-derived Bacterium Streptoverticillium luteoverticillatum 11014 Ⅱ

查看全文 作　　者：LI Dehai ZHU Tianjiao FANG Yuchun LIU Hongbing GU Qianqun ZHU [1]Weiming 高影响力作者 机构地区：[1]Key Laboratory of Marine Drug Chinese Ministry of Education, Institute of A larine Drug and Food,Ocean University of China, Qingdao 266003, P. R. China高影响力机构 出　　处：《Journal of Ocean University of China》索引2007年第6卷第2期,共3页高影响力期刊 基　　金：The work was financially supported by the Project of Chinese National Programs for High Technology Research and Development(No.2003AA624020);the National Nattual Science Foundation of China(Nos.30472136 and 30470196). 摘　　要：Eight known compounds were isolated from a marine-derived bacterium Streptoverticillium luteoverticillatum 11014 using bioassay-guided fractionations. Their structures were identified by spectral analysis as bis (4-hydroxybenzyl) ether (1), p-hydroxyphenylethyl alcohol (2), N-(4-hydroxyphenethyl) acetamide (3), indole-3 carboxylic acid methyl ester (4), dibenzo[b,e] [1,4]dioxine (5), thymine (6), cytosine deoxyribonucleoside (7) and 2, 3-butanediol (8). These compounds were evaluated for their cytotoxic activities against K562 cell line with the SRB method for the first time. Compounds 2 and 4 showed cytotoxcities with IC50 values of 101.1 and 165.3 μmol L-1, respectively. All compounds were isolated from S. luteoverticillatum 11014 for the first time. 关 键 词：海洋细菌 海洋放线菌 抗肿瘤成分 分离
相关文献

参考文献(1)

引证文献(4)

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1　渝公网安备 50019002500403号　违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费