Clinicopathological Characteristics as Predictive Factrs for Lymph Node Metastasis in Submucosal Gastric Cancer

查看全文 作　　者：Caigang Liu Ping Lu Yang Lu Lua Li Ruishan Zhang Huimian Xu Shubao Wang Junqing [1]Chen

机构地区：[1]Department of Oncology, First Affiliated Hospital of China Medial University, Shenyang 110001. China.

出　　处：《Chinese Journal of Clinical Oncology》索引2007年第4卷第4期,共4页

基　　金：grants from the National Natural Science Foundation of Chi-na (No.30471678);the Natural Science Foundation of Liaoning (No.200420741) 摘　　要：OBJECTIVE To identify clinicopathological characteristics as predictive factors for lymph node metastasis in submucosal gastric cancer, and in addi- tion to establish objective criteria as indications for endoscopic submucosal dissection (ESD). METHODS Data from 130 patients with submucosal gastric cancer were collected, and the relationship between their clinicopathological characteris- tics and the presence of lymph node metastasis was retrospectively analyzed by multivariate analysis. RESULTS In the multivariate logistic regression model, a tumor size of 2 cm or more and an undifferentiated histologic type were found to be inde- pendent risk clinicopathological characteristics for lymph node metastasis. Among 130 patients with submucosal carcinoma, no lymph node metastases were observed in 17 patients who showed neither of the two risk clinicopath- ological characteristics. Lymph node metastasis occurred in 61.1% (22/36) of the patients who had both risk clinicopathological characteristics. CONCLUSION A tumor size of 2 cm or more and an undifferentiated histologic type were significantly and independently related to lymph node metastasis in submucosal gastric cancer. It is rational for the paitients with neither of these two independent risk clinicopathological characteristics to undergo an ESD. 关键词：胃癌淋巴结转移临床病理学临床表现

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Clinicopathological Characteristics as Predictive Factrs for Lymph Node Metastasis in Submucosal Gastric Cancer

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