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Carcinosarcoma of the stomach:A case report and review of the literature

查看全文 作  者:Tomislav [1]Randjelovic;Branka [2]Filipovic;Darko [3]Babic;Vesna [4]Cemerikic;Branislav [5]Filipovic 高影响力作者 机构地区:[1]Department of Gastrointestinal Surgery,Clinical and Hospital Center 'Bezanijska Kosa,' Belgrade,Serbia;[2]Department of Gastroenterohepatology Clinical and Hospital Center 'Bezanijska Kosa,' Belgrade 11080,Serbia;[3]Department of Pathology,Clinical and Hospital Center 'Bezanijska Kosa,' Belgrade 11080,Serbia;[4]Laboratory for Histopathological and Cytological Diagnostics 'Histolab,' Belgrade 11080,Serbia;[5]Institute of Anatomy,School of Medicine,University of Belgrade,Belgrade 11080,Serbia高影响力机构 出  处:《World Journal of Gastroenterology》索引2007年第13卷第41期,共4页高影响力期刊 摘  要:Carcinosarcomas are rare,malignant,biphasic tumors. We report the case of a 62-year-old man with gastric carcinosarcoma,along with its clinical,macroscopic and histopathological features. Macroscopically,a specimen of deformed stomach was obtained that measured 200 mm×150 mm×100 mm. A 150 mm×100 mm× 50 mm exophytic tumoral mass (Borrmann typeⅠ) was found,which involved the posterior wall from the cardia to the antrum. Histopathologically,a mixed type of malignancy was revealed: an adenocarcinoma with intestinal metaplasia,with interposed fascicles of fusiform atypical cells and numerous large,rounded and oval cells. The tumor showed positive histochemistry for cytokeratin 18,epithelial membrane antigen,carcinoembryonic antigen,chromogranin A and vimentin. Liver metastases were diagnosed 8 mo postoperatively,and the patient died 4 mo later. A review of the available literature is also presented. 关 键 词:癌肉瘤 组织化学 病理学
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