Combined choriocarcinoma, neuroendocrine cell carcinoma and tubular adenocarcinoma in the stomach

查看全文 作　　者：Yasumitsu [1]Hirano;Takuo [2]Hara;Hiroshi [2]Nozawa;Kaeko [2]Oyama;Naohiro [2]Ohta;Kenji [1]Omura;Go [1]Watanabe;Hideki [3]Niwa

机构地区：[1]Department of General and Cardiothoracic Surgery, Kanazawa University Graduate school of Medical Science 13-1, Takara-machi, Kanazawa 920-8641, Japan;[2]Department of Surgery, Kouseiren Takaoka Hospital5-10, Eiraku-chou, Takaoka 933-8555, Japan;[3]Department of Pathology, Kouseiren Takaoka Hospital 5-10, Eiraku-chou, Takaoka 933-8555, Japan

出　　处：《World Journal of Gastroenterology》索引2008年第14卷第20期,共4页

摘　　要：We described a patient with adenocarcinoma of the stomach combined with choriocarcinoma and neuroendocrine cell carcinoma. An 85-year-old man visited our hospital because of appetite loss. Gastric fiberscopy revealed a large tumor occupying the cardial region and anterior wall of the gastric body. The patient underwent total gastrectomy with lymphnode dissection and partial resection of the liver. Choriocarcinoma, small cell carcinoma and tubular adenocarcinoma existed in the gastric tumor. The choriocarcinomatous foci contained cells positive for beta-subunit of human chorionic gonadotropin (B-hCG) and human placental lactogen mainly in syncytiotrophoblastic cells. The small cell carcinomatous foci contained cells positive for synaptophysin, neuron-specific enolase (NSE), and chromogranin A. The prognosis for gastric adenocarcinoma with choriocarcinoma and neuroendocrine cell carcinoma is exceedingly poor. This patient died about 2 mo after the first complaint from hepatic failure. This is the first reported case of gastric cancer with these three pathological features. 关键词：绒毛膜癌胃癌管腺癌治疗

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Combined choriocarcinoma, neuroendocrine cell carcinoma and tubular adenocarcinoma in the stomach

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