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Ultrahigh resolution optical coherence tomography with femtosecond Ti:sapphire laser and photonic crystal fiber

查看全文 作  者:XUE [1]Ping;James G [2]FUJIMOTO 高影响力作者 机构地区:[1]Department of Physics, Laboratory of Atomic and Molecular Nanosciences of Ministry of Education, Tsinghua University, Beijing 100084, China;[2]Department of Electrical Engineering and Computer Science, Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139-4307, USA高影响力机构 出  处:《Chinese Science Bulletin》索引2008年第53卷第13期,共4页高影响力期刊 基  金:the National Basic Research Program of China (Grant No.001CB510307);Hi-tech Research and Development Program of China (Grant No.2006AA02Z472);National Natural Science Foundation of China (Grant Nos.90508001,10574081);the Ministry of Education of China (Grant No.306020) 摘  要:Optical coherence tomography (OCT) with ultrahigh axial resolution was achieved by the super-contin-uum generated by coupling femtosecond pulses from a commercial Ti:sapphire laser into an air-silica microstructure fiber. The visible spectrum of the super-continuum from 450 to 700 nm centered at 540 nm can be generated. A free-space axial OCT resolution of 0.64 μm was achieved. The sensitivity of OCT system was 108 dB with incident light power 3 mW at sample,only 7dB below the theoretical limit. Subcellular OCT imaging was also demonstrated,showing great potential for biomedical application. 关 键 词:X线摄影 连续介质 晶体纤维 蓝宝石激光
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