Tongue-like Barrett's esophagus is associated with gastroesophageal reflux disease

查看全文 作　　者：Hatsushi [1]Yamagishi;Tomoyuki [1]Koike;Shuichi [1]Ohara;Shigeyuki [1]Kobayashi;Ken [1]Ariizumi;Yasuhiko [1]Abe;Katsunori [1]Iijima;Akira [1]Imatani;Yoshifumi [2]Inomata;Katsuaki [2]Kato;Daisuke [2]Shibuya;Shigemitsu [3]Aida;Tooru [1]Shimosegawa 机构地区：[1]Division of Gastroenterology,Tohoku University Graduate School of Medicine,Sendai 980-8574,Japan;[2]Miyagi Cancer Society,Sendai,980-0011,Japan;[3]Department of Gastroenterlogy,Sendai City Hospital,Sendai 984-8501,Japan 出　　处：《World Journal of Gastroenterology》索引2008年第14卷第26期,共8页 摘　　要：AIM:To test this hypothesis of barrett esophagus (BE) classified into two types and to further determine if there was any correlation between the shape of endoscopically suspected esophageal metaplasia (ESEM), prevalence of reflux esophagitis (RE) and heartburn. METHODS: A total of 6504 Japanese who underwent endoscopy for their annual stomach check-up were enrolled in this study. BE was detected without histological confirmation that is ESEM. We originally classified cases of ESEM into 3 types based on its shape: Tongue-like (T type), Dome-like (D type) and Wave-like (W type) ESEM. The respective subjects were prospectively asked to complete questionnaires concerning the symptoms of heartburn, dysphagia, and abdominal pain for a one-month period. RESULTS: ESEM was observed in 10.3% of 6504 subjects (ESEM < 1 cm, 9.4%; 1 cm ≤ ESEM < 3 cm, 1.7%; ESEM ≥ 3 cm, 0.5%). The frequency of ESEM was significantly higher in males compared with female subjects. Statistical analysis showed that the prevalence of heartburn and RE were significantly higher in the T type ESEM than in the W type ESEM (P < 0.05). CONCLUSION: The T type ESEM was strongly associated with reflux symptoms and RE whereas the W type ESEM was not associated with GERD. 关 键 词：消化系统疾病 胃食管反流病 消化功能 巴雷特食道