The spatiotemporal expression changes of 16 epididymis-specific genes induced by testosterone, heat, and combination treatment in cynomolgus monkey

查看全文 作　　者：Xiangqi [1,2]Li;Qiang [2]Liu;Shigui [1]Liu;Xuesen [4]Zhang;Yixun [4]Liu;Yonglian [2,3]Zhang

机构地区：[1]College of Life Science, Sichuan University, Chengdu 610064, China;[2]Shanghai Key Laboratory for Molecular Andrology, State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China;[3]Shanghai Institute of Planned Parenthood Research, Shanghai 200032, China;[4]State Key Laboratory of Reproductive Biology. Institute of Zoology, Chinese Academy of Sciences, Beijing 100080, China

出　　处：《Acta Biochimica et Biophysica Sinica》索引2008年第40卷第8期,共8页

基　　金：This study was supported by the grants from the National Natural Science Foundation of China (30230190 and 30570684), the National Basic Science Research and Development Project (2006CB504002 and 2006CB944002 ) and the Chinese Academy of Sciences Knowledge Innovation Program (No. KSCX1-YW-R-54)Acknowledgements The authors are grateful to the researchers at the State Key Laboratory of Reproductive Biology, the Institute of Zoology, the Chinese Academy of Sciences for their assistance in preparing this report. Also, the authors would like to thank the Guangxi Hongfeng Primate Research Center and the Institute of Biological Products of Beijing for their assistance with animal healthcare. 摘　　要：包含阴囊的温暖的处理的试验性的不孕模型,睾丸激素植入,并且联合二被开发证实联合处理在 cynomolgus 在细菌房间 apoptosis 上导致的一个 synergistic 行动猴子睾丸。用这个模型, 16 的时间空间的表示变化报导了或在 epididymis 的新奇基因被调查在 epididymal 基因上检验处理的效果。这被表明这些区域特定的基因,其中一些地区性没被修理,随着这些处理极大地变化了。这些 epididymal 基因的表示层次波动,并且大多数基因的表示在处理的结束回到了将近正常的水平。而且,源于联合处理的表示变化不比那些源于单个处理更重要。这建议联合处理在 epididymal 基因的表示上有一个对抗行动并且它的效果不是象二个单个处理的同样在 epididymis 上不利的。 关键词：附睾种基因睾丸激素猕猴基因表达男性荷尔蒙

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The spatiotemporal expression changes of 16 epididymis-specific genes induced by testosterone, heat, and combination treatment in cynomolgus monkey

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