反相高效液相色谱法同时检测片剂中的头孢呋辛酯及奥硝唑(英文)

查看全文 作　　者：RANJANE Poonam [1]N;GANDHI Santosh [1]V;KADUKAR Sayali [1]S;RANHER Sandeep [1]S

机构地区：[1]Department of Pharmaceutical Analysis,A.I.S.S.M.S.College of Pharmacy

出　　处：《色谱》索引2008年第26卷第6期,共3页

摘　　要：A simple,accurate and sensitive reversed-phase high performance liquid chromatographic(RP-HPLC)method for the simultaneous determination of cefuroxime axetil and ornidazole in combined tablet dosage form has been developed.The method was performed with a HiQ-SiL C18 column(250 mm×4.6 mm)and photodiode array(PDA)detector,using 0.01 mol/L potassium dihydrogen orthophosphate-methanol(56∶44,v/v)as the mobile phase and tinidazole as the internal standard.Beer's law obeys in the concentration ranges of 5-25 μg/mL and 10-50 μg/mL for cefuroxime axetil and ornidazole,respectively.The method has been successfully validated statistically and applied for the analysis of the drugs in pharmaceutical formulation. 关键词：测定方法头孢呋辛酯奥硝唑片剂药物分析反相高效液相色谱法

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反相高效液相色谱法同时检测片剂中的头孢呋辛酯及奥硝唑(英文)

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