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Role of upper endoscopy in diagnosing opportunistic infections in human immunodeficiency virus-infected patients

查看全文 作  者:Ana Luiza Werneck-[1]Silva;Ivete Bedin [2]Prado 高影响力作者 机构地区:[1]Casa da AIDS-Infectious Disease Division,School of Medicine,University of So Paulo,Rua Frei Caneca 255,CEP:05403-000,So Paulo,Brazil;[2]University of So Paulo,Hospital das Clínicas da FMUSP Av. Ovídio Pires de Campos,225,6 andar CEP:05403-010,So Paulo,Brazil高影响力机构 出  处:《World Journal of Gastroenterology》索引2009年第15卷第9期,共7页高影响力期刊 摘  要:Highly active antiretroviral therapy (HAART) has dramatically decreased opportunistic infections (OIs) in human immunodef iciency virus (HIV)-infected patients. However,gastrointestinal disease continues to account for a high proportion of presenting symptoms in these patients. Gastrointestinal symptoms in treated patients who respond to therapy are more likely to the result of drug-induced complications than OI. Endoscopic evaluation of the gastrointestinal tract remains a cornerstone of diagnosis,especially in patients with advanced immunodeficiency,who are at risk for OI. The peripheral blood CD4 lymphocyte count helps to predict the risk of an OI,with the highest risk seen in HIV-infected patients with low CD4 count (< 200 cells/mm3). This review provides an update of the role of endoscopy in diagnosing OI in the upper gastrointestinal tract in HIV-infected patients in the era of HAART. 关 键 词:人类免疫缺陷病毒 艾滋病毒感染者 机会性感染 内镜诊断 CD4淋巴细胞计数 抗逆转录病毒疗法 CD4细胞计数 鸡尾酒疗法
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