Non-alcoholic steatohepatitis with normal aminotransferase values

查看全文 作　　者：Hüseyin Saadettin [1]Uslusoy;Selim Giray [1]Nak;Macit [1]Gülten;Zeynep B|y|kl|[2]

机构地区：[1]Department of Gastrenterology,Uludag University Medical School;[2]Department of Biostatistics,Ankara University School of Medicine

出　　处：《World Journal of Gastroenterology》索引2009年第15卷第15期,共6页

基　　金：Uludag University Scientific Project Grant 摘　　要：AIM:To investigate the aspects of liver histology in patients with non-alcoholic steatohepatitis(NASH)who had normal aminotransferase levels. METHODS:Thirty-four patients diagnosed with liver steatosis by ultrasonographic examination participated in the study.We compared all nonalcoholic fatty liver disease and NASH cases,according to aminotransferase level,aspartate aminotransferase (AST)/alanine aminotransferase(ALT)ratio and presence of metabolic syndrome. RESULTS:Sixteen of 25 patients with high aminotransferase levels were diagnosed with NASH and nine with simple fatty liver according to liver histology. Among the nine patients with normal aminotransferase levels,seven had NASH and two had simple fatty liver. The patients with normal and high liver enzyme levels had almost the same prevalence of NASH and metabolic syndrome.Liver histology did not reveal any difference according to aminotransferase levels and AST/ALT ratio. CONCLUSION:Aminotransferase levels and AST/ALT ratio do not seem to be reliable predictors for NASH. Despite numerous non-invasive biomarkers,all patients with fatty liver should undergo liver biopsy. 关键词：非酒精性脂肪性肝炎转氨酶水平非酒精性脂肪性肝病脂肪肝患者代谢综合征酶值肝组织学非酒精性肝炎

相关文献

参考文献（11）
引证文献（7）
耦合文献（33）

参考文献(11)

引证文献(7)

耦合文献(33)

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

Non-alcoholic steatohepatitis with normal aminotransferase values

参考文献(11)

引证文献(7)

耦合文献(33)

用户提示