Impact of social isolation and resident intruder stress on aggressive behavior in the male rat

查看全文 作　　者：Sheng Wei Huiyun Zhang Jie Gao Ling Xue Peng Sun Yubin Chao Gang Xue Mingqi [1]Qiao

机构地区：[1]Key Laboratory of Classic Theories on Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ministry of Education, Jinan 250355, Shandong Province, China

出　　处：《Neural Regeneration Research》索引2010年第5卷第15期,共5页

基　　金：the National Natural Science Foundation of China,No.30973688;the National Program of Key Basic Research Project(973Program),No.2006CB504804 摘　　要：Stress studies frequently utilize physical stressors to establish animal models of stress.In the majority of cases,these models are not consistent with human circumstances.The present study simulated a social isolation plus resident intruder stress model in the rat.The rats were subjected to daily social isolation and resident intruder stress for 2 weeks.Behaviors were then tested.Rats subjected to social stress exhibited different aggressive behavior styles;some rats had greater scores on composite aggression behaviors,as well as locomotor and exploratory activity,but lower scores on latency than others.The high-aggressive group exhibited predominantly anger-out,while the low-aggressive group exhibited anger-in.Results suggest that social isolation plus resident intruder may serve as an appropriate model for anger-in and anger-out emotion modeling in the rat. 关键词：雄性大鼠攻击行为入侵者压力表社会居民动物模型应激

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Impact of social isolation and resident intruder stress on aggressive behavior in the male rat

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