Effects of electroacupuncture on microcirculatory blood flow and glucose transporter function in the hippocampus

查看全文 作　　者：Lu, [1]Yan;Han, [2]Bingbing;Wang, [1]Shijun

机构地区：[1]Shandong Univ Tradit Chinese Med, Dept Expt Acupuncturol, Acupuncture & Moxibust Coll, Jinan 250355, Shandong, Peoples R China;[2]Shandong Univ Tradit Chinese Med, Microcirculat Lab, Basic Med Coll, Jinan 250355, Shandong, Peoples R China;

出　　处：《Neural Regeneration Research》索引2011年第6卷第3期,共6页

基　　金：the National Natural Science Foundation of China,No. 30672717 摘　　要：Nerve cell metabolism in post brain ischemia depends on increased microcirculation perfusion and transport function of microvascular endothelial cells.In the present study,a rat model of middle cerebral artery occlusion was established to investigate the influence of electroacupuncture(EA) on hippocampal CA1 cerebral blood flow and glucose transporter 1(GLUT1) expression in the microvascular endothelial cells.Following EA at Neiguan(PC 6),the cerebral blood flow in the ischemic hippocampal CA1 region was significantly elevated,the number and microvascular integrated absorbance of the GLUT1-positive cells were significantly increased,nerve cell damage was ameliorated,and GLUT1 protein expression in the ischemic hippocampus was significantly increased.Results demonstrate that EA increased the cerebral blood flow of the hippocampal CA1 region and improved the glucose transport function,thereby attenuating neuronal injuries. 关键词：葡萄糖转运蛋白海马CA1区微循环微血管内皮细胞体功能血流量电对运输功能

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Effects of electroacupuncture on microcirculatory blood flow and glucose transporter function in the hippocampus

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