Nasopharyngeal carcinoma in the Northeastern states of India

查看全文 作　　者：Amal Chandra [1]Kataki;Malcolm J. [2,3,4]Simons;Ashok Kumar [5]Das;Kalpana [6]Sharma;Narinder Kumar [7]Mehra

机构地区：[1]Regional Institute for Cancer Treatment & Research, Dr. B. Borooah Cancer Institute, Guwahati;[2]Department of Experimental Research, Sun Yat-sen University Cancer Center,Guangzhou;[3]Simons Haplomics Limited;[4]Hong Kong SAR, P. R. China;[5]Department of Head & Neck Oncology, Dr. B. Borooah Cancer Institute, Guwahati;[6]Department of Otolaryngorhinology, Gauhati Medical College, Assam;[7]Department of Transplant Immunology & Immunogenetics, All India Institute of Medical Sciences

出　　处：《Chinese Journal of Cancer》索引2011年第30卷第2期,共8页

摘　　要：Nasopharyngeal cancer (NPC) is a rare disease in most parts of the world, except for Southeast Asia, some parts of North Africa and the Arctic. It is mostly seen in people of Chinese origin. In India, NPC is also rare, except for the Hill States of Northeast India, particularly Nagaland, Manipur, and Mizoram. The striking feature of NPC in Northeast India is that the incidence ranges over the complete spectrum from the lowest (as 0.5/100 000 to 2.0/100 000 among Caucasoid) to the highest (as ~20/100 000 among Cantonese/Zhongshan dialect Chinese). The age-adjusted rate of NPC in Kohima district of Nagaland State is 19.4/100 000, which is among the highest recorded rates. By contrast, in Assam, one of the so-called Hill States but not itself a hilly state, NPC is much less common. The Northeastern region is distinguished by a preponderance of the Tibeto-Burman languages and by variable mongoloid features among peoples of the region. The nature of the migratory populations who are presumed to be bearers of the mongoloid risk is unknown, but these NPC occurrence features provide an outstanding opportunity for NPC risk investigation, such as that of the hypothesis of Wee et al. for westward displacement of Chinese aborigines following the last glacial maximum. 关键词：东北部鼻咽癌印度全国人民代表大会东北地区蒙古人种末次盛冰期特征变量

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Nasopharyngeal carcinoma in the Northeastern states of India

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