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Surgicopathological classification of hepatic space-occupying lesions:A single-center experience with literature review

查看全文 作　　者：Wen-Ming [1]Cong;Hui [1]Dong;Lu [1]Tan;Xu-Xu [1]Sun;Meng-Chao [2]Wu 高影响力作者 机构地区：[1]Department of Pathology, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China;[2]Department of Surgery, Eastern Hepatobili- ary Surgery Hospital, Second Military Medical University, 225 Changhai Road, Shanghai 200438, China高影响力机构 出　　处：《World Journal of Gastroenterology》索引2011年第17卷第19期,共7页高影响力期刊 基　　金：Supported by The National Nature Science Foundation of China,No.30872506 and No.81072026 摘　　要：Accompanying rapid developments in hepatic surgery,the number of surgeries and identifications of histological types of primary hepatic space-occupying lesions (PHSOLs) have increased dramatically.This has led to many changes in the surgicopathological spectrum of PHSOLs,and has contributed to a theoretical basis for modern hepatic surgery and oncological pathology.Between 1982 and 2009 at the Eastern Hepatobiliary Surgery Hospital (EHBH) in Shanghai,31 901 patients underwent surgery and were diagnosed as having a PHSOL.In this paper,we present an analysis of the PHSOL cases at the EHBH for this time period,along with results from a systematic literature review.We describe a surgicopathological spectrum comprising more than 100 types of PHSOLs that can be stratified into three types:tumor-like,benign,and malignant.We also stratified the PHSOLs into six subtypes derived from hepatocytes;cholangiocytes;vascular,lymphoid and hemopoietic tissues;muscular,fibrous and adipose tissues;neural and neuroendocrine tissues;and miscellaneous tissues.The present study provides a new classification system that can be used as a current reference for clinicians and pathologists to make correct diagnoses and differential diagnoses among various PHSOLs. 关 键 词：肝脏细胞 分类系统 文献 病变 占位 神经内分泌 复习 造血组织
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