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Abscisic Acid Receptors:Past,Present and Future

查看全文 作  者:Jianjun [1,2]Guo;Xiaohan [3]Yang;David J. [3]Weston;Jin-Gui [3]Chen 高影响力作者 机构地区:[1]Department of Genetics, Harvard Medical School, Boston, Massachusetts 02114-2790, USA;[2]Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114-2790, USA;[3]Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831-6422, USA高影响力机构 出  处:《Journal of Integrative Plant Biology》索引2011年第53卷第6期,共11页高影响力期刊 摘  要:Abscisic acid(ABA) is the key plant stress hormone.Consistent with the earlier studies in support of the presence of both membrane-and cytoplasm-localized ABA receptors,recent studies have identified multi-ple ABA receptors located in various subcellular locations.These include a chloroplast envelope-localized receptor(the H subunit of Chloro-plast Mg2+-chelatase/ABA Receptor),two plasma membrane-localized receptors(G-protein Coupled Receptor 2 and GPCR-type G proteins),and one cytosol/nucleus-localized Pyrabactin Resistant(PYR)/PYR-Like(PYL)/Regulatory Component of ABA Receptor 1(RCAR).Although the downstream molecular events for most of the identified ABA receptors are currently unknown,one of them,PYR/PYL/RCAR was found to directly bind and regulate the activity of a long-known central regulator of ABA signaling,the A-group protein phosphatase 2C(PP2C).Together with the Sucrose Non-fermentation Kinase Subfamily 2(SnRK2s) protein kinases,a central signaling complex(ABA-PYR-PP2Cs-SnRK2s) that is responsible for ABA signal perception and transduction is supported by abundant genetic,physiological,biochemical and structural evidence.The identification of multiple ABA receptors has advanced our understanding of ABA signal perception and transduction while adding an extra layer of complexity. 关 键 词:G蛋白偶联受体 脱落酸 ABA 蛋白激酶 亚细胞位置 本地化 组成部分 分子事件
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