Immunomodulatory effects of Caulerpa racemosa var peltata polysaccharide and its selenizing product on T lymphocytes and NK cells in mice

查看全文 作　　者：SHEN [1]WeiZai;WANG [1]Hui;GUO [1]GuoQing;TUO [1,2]JingJing

机构地区：[1]Department of Anatomy,Medical College,Jinan University,Guangzhou 510630,China;[2]Ultrasonic Division,Municipal Hospital of Weihai,Shandong 264200,China

出　　处：《Science China(Life Sciences)》索引2008年第51卷第9期,共7页

基　　金：the Team Project of Guangdong Natural Science Foundation(Grant No.039213) 摘　　要：A polysaccharide, CrvpPS, was isolated from Caulerpa racemosa var peltata. It was reacted with nano-selenium in distilled water containing ascorbic acid (Vit C) to form a stable CrvpPS-nano-Se complex. The immunomodulatory effects of CrvpPS and CrvpPS-nano-Se on T lymphocytes subgroups and NK cells in mice were investigated. After intragastric administration for 10 days separately, both CrvpPS and CrvpPS-nano-Se showed significant stimulatory functions to thymus gland of mice. Moreover, the CrvpPS-nano-Se induced the percentage of CD3+, CD3+CD4+, NK cells and the CD4+/CD8+ value to increase significantly (P<0.05) when analyzed by flow cytometry, which is better than the CrvpPS, sucrose-nano-Se, and even the positive drug levamisole. 关键词：Caulerpa racemosa var peltata polysaccharides(CrvpPS) nano-Se T lymphocyte subgroups natural killer cells IMMUNOMODULATION flow cytometric analysis

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Immunomodulatory effects of Caulerpa racemosa var peltata polysaccharide and its selenizing product on T lymphocytes and NK cells in mice

参考文献(25)

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