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Current treatment for colorectal liver metastases

查看全文 作  者:Evangelos P [1]Misiakos;Nikolaos P [2]Karidis;Gregory [2]Kouraklis 高影响力作者 机构地区:[1]Third Department of Surgery,Medical School,University of Athens,Attikon University Hospital,Athens 12462,Greece;[2]Second Propedeutic Department of Surgery,Medical School,University of Athens,General Hospital Laiko,Athens 11527,Greece高影响力机构 出  处:《World Journal of Gastroenterology》索引2011年第17卷第36期,共9页高影响力期刊 摘  要:Surgical resection offers the best opportunity for survival in patients with colorectal cancer metastatic to the liver,with five-year survival rates up to 58% in selected cases.However,only a minority are resectable at the time of diagnosis.Continuous research in this field aims at increasing the percentage of patients eligible for resection,refining the indications and contraindications for surgery,and improving overall survival.The use of surgical innovations,such as staged resection,portal vein embolization,and repeat resection has allowed higher resection rates in patients with bilobar disease.The use of neoadjuvant chemotherapy allows up to 38% of patients previously considered unresectable to be significantly downstaged and eligible for hepatic resection.Ablative techniques have gained wide acceptance as an adjunct to surgical resection and in the management of patients who are not surgical candidates.Current management of colorectal liver metastases requires a multidisciplinary approach,which should be individualized in each case. 关 键 词:大肠癌 肝脏 手术切除 治疗 因材施教 患者 生存率 切除术
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