Microwave assisted synthesis of novel Hantzsch 1,4-dihydropyridines,acridine-1,8-diones and polyhydroquinolines bearing the tetrazolo[1,5-α]quinoline moiety and their antimicrobial activity assess

查看全文 作　　者：Niraj [1]K.Ladani;Divyesh [1]C.Mungra;Manish [1]P.Patel;Ranjan [1]G.Patel

机构地区：[1]Department of Chemistry,Sardar Patel University,Vallabh Vidyanagar 388120,Gujarat,India

出　　处：《Chinese Chemical Letters》索引2011年第22卷第12期,共4页

摘　　要：Microwave assisted efficient Hantzsch reaction via four-component coupling reactions of tetrazolo[1,5-α]quinoline-4-carbal-dehyde, dimedone/cyclohexane-1,3-dione,ethyl/methyl acetoacetate and ammonium acetate was described as the preparation of tetrazolo[1,5-α]quinoline based 1,4-dihydropyridines,acridine-1,8-diones and polyhydroquinolines.The process presented here is simple,rapid,environmentally welcoming and high yielding.All the derivatives were subjected to an in vitro antimicrobial screening against a representative panel of bacteria and fungi and results worth further investigations. 关键词：微波辅助合成抗菌活性二酮喹啉二氢轴承评估成分

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Microwave assisted synthesis of novel Hantzsch 1,4-dihydropyridines,acridine-1,8-diones and polyhydroquinolines bearing the tetrazolo[1,5-α]quinoline moiety and their antimicrobial activity assess

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