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Synthesis,characterization and antimicrobial activity of some new biquinoline derivatives containing a thiazole moiety

查看全文 作  者:Nirav [1]K.Shah;Nimesh [1]M.Shah;Manish [1]P.Patel;Ranjan [1]G.Patel 高影响力作者 机构地区:[1]Department of Chemistry,Sardar Patel University,Vallabh Vidyanagar 388120,Gujarat,India高影响力机构 出  处:《Chinese Chemical Letters》索引2012年第23卷第4期,共4页高影响力期刊 摘  要:A series of new biquinoline derivatives containing a thiazole moiety were synthesized by a one-pot,base-catalyzed cyclocondensation reaction of 2-chloro-3-formyl quinoline,malononitrile and enaminone.All the synthesized compounds were characterized by elemental analysis,FT-IR,~1H NMR and ^(13)C NMR data.All the synthesized compounds were screened against three bacterial pathogens,namely Bacillus cereus,B.substilis and Escherichia coli and for antifungal activity against three fungal pathogens,Aspergillus niger,Fusarium oxisporum and Rhizopus using the disc diffusion method. 关 键 词:喹啉衍生物 反应合成 噻唑基 抗菌活性 表征 蜡样芽胞杆菌 大肠埃希氏菌 纸片扩散法
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