Stem cell differentiation and human liver disease

查看全文 作　　者：Wen-Li [1,2]Zhou;Claire N [2]Medine;Liang [1]Zhu;David C [2]Hay

机构地区：[1]Department of Gastroenterology,Changzheng Hospital, Second Military Medical University ofChina, Shanghai 200003, China;[2]Medical Re-search Council Centre for Regenerative Medicine, University ofEdinburgh, Edinburgh EH 16 4UU, Scotland, United Kingdom

出　　处：《World Journal of Gastroenterology》索引2012年第18卷第17期,共8页

基　　金：Supported by A RCUK fellowship,EP/E500145/1,to Hay DC;A grant from the Edinburgh Bioquarter,to Medine CN;China Scholarship Council,No.2010658022,to Zhou WL 摘　　要：Human stem cells are scalable cell populations capable of cellular differentiation.This makes them a very attractive in vitro cellular resource and in theory provides unlimited amounts of primary cells.Such an approach has the potential to improve our understanding of human biology and treating disease.In the future it may be possible to deploy novel stem cell-based approaches to treat human liver diseases.In recent years,eff icient hepatic differentiation from human stem cells has been achieved by several research groups including our own.In this review we provide an overview of the f ield and discuss the future potential and limitations of stem cell technology. 关键词：干细胞技术人类生物学肝脏疾病分化能力疾病治疗原代细胞细胞群可伸缩

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Stem cell differentiation and human liver disease

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