Double network hydrogel with high mechanical strength:Performance,progress and future perspective

查看全文 作　　者：CHEN [1,2]YongMei;DONG [1]Kun;LIU [1]ZhenQi;XU [3]Feng

机构地区：[1]MOE Key Laboratory for Non-Equilibrium Synthesis and Modulation of Condensed Matter,Department of Chemistry,School of Science,Xi'an Jiaotong University,Xi'an 710049,China;[2]Biomedical Engineering and Biomechanics Center,Xi'an Jiaotong University,Xi'an 710049,China;[3]College of Chemistry&Material Science,Shaanxi Normal University,Xi'an 710062,China

出　　处：《Science China(Technological Sciences)》索引2012年第55卷第8期,共14页

基　　金：supported by the National Natural Science Foundation of China (Grant Nos. 51073127,51173144 );the Higher School Specialized Research Fund for the Doctoral Program FundingIssue (Grant No. 20100201110040 );the Operation Expenses for Universities’ Basic Scientific Research of Central Authorities (Grant No. 0109-08140018 );the New Research Support Project (Grant No. 08141001) from Xi’an Jiaotong University,P. R. China 摘　　要：With high water content(~90 wt%) and significantly improved mechanical strength(~MPa),double network(DN) hydrogels have emerged as promising biomaterials with widespread applications in biomedicine.In recent years,DN hydrogels with extremely high mechanical strength have achieved great advance,and scientists have designed a series of natural and biomimetic DN hydrogels with novel functions including low friction,low wear,mechanical anisotropy and cell compatibility.These advances have also led to new design of biocompatible DN hydrogels for regeneration of tissues such as cartilage.In this paper,we reviewed the strategies of designing high-strength DN hydrogel and analyzed the factors that affect DN hydrogel properties.We also discussed the challenges and future development of the DN hydrogel in view of its potential as biomaterials for their biomedical applications. 关键词：机械强度水凝胶凝胶性能双网络进度生物材料应用程序细胞相容性

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Double network hydrogel with high mechanical strength:Performance,progress and future perspective

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