Shiga toxin-producing Escherichia coli O104:H4: An emerging 0important pathogen in food safety

查看全文 作　　者：CUI [1,2]YuJun;LI [2]DongFang;YANG [1,2]RuiFu

机构地区：[1]State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology;[2]BGI-Shenzhen

出　　处：《Chinese Science Bulletin》索引2013年第58卷第14期,共7页

基　　金：supported by the National Basic Research Program of China(2009CB522600);Shenzhen Biological Industry Development Special Foundation-Basic Research Key Projects (JC201005250088A) 摘　　要：In 2011, Shiga toxin-producing Escherichia coli O104 : H4 resulted in a large outbreak of bloody diarrhea and hemolytic uremic syndrome (HUS) in Germany and 15 other countries in Europe and North America. This event raised a serious public health crisis and caused more than two billion US dollars in economic losses. In this review, we describe the classification of E. coli, the Germany outbreak, and the characteristics and epidemical source-tracing of the causative agent. We also discuss the genomics analysis of the outbreak organism and propose an open-source genomics analysis as a new strategy in combating the emerging infectious diseases. 关键词：大肠杆菌志贺毒素病原体食品安全大肠埃希菌公共卫生经济损失流行病学

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Shiga toxin-producing Escherichia coli O104:H4: An emerging 0important pathogen in food safety

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